Synthesis and biological evaluation of bilobol and adipostatin A
Publication type: Journal Article
Publication date: 2011-04-01
scimago Q2
wos Q3
SJR: 0.351
CiteScore: 3.1
Impact factor: 1.3
ISSN: 10286020, 14772213
PubMed ID:
21462031
Organic Chemistry
Drug Discovery
General Medicine
Pharmacology
Pharmaceutical Science
Molecular Medicine
Complementary and alternative medicine
Analytical Chemistry
Abstract
Concise total synthesis of bilobol 5-pentadecenylresorcinol (1), isolated from Gingko biloba fruits, has been achieved in 10 steps with 51% overall yield from 3,5-dihydroxybenzoic acid (3). Adipostatin A (2), isolated from the fruits as well as from Streptomyces cyaneus 2299-SV1, has also been synthesized in two steps from methylated bilobol (10). The structure-activity relationship study of synthetic products was described by means of cytotoxic assay against human KB carcinoma cell lines.
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Metrics
27
Total citations:
27
Citations from 2024:
3
(11.11%)
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MLA
Cite this
GOST
Copy
Tanaka A. et al. Synthesis and biological evaluation of bilobol and adipostatin A // Journal of Asian Natural Products Research. 2011. Vol. 13. No. 4. pp. 290-296.
GOST all authors (up to 50)
Copy
Tanaka A., Arai Y., Kim S., HAM J., Usuki T. Synthesis and biological evaluation of bilobol and adipostatin A // Journal of Asian Natural Products Research. 2011. Vol. 13. No. 4. pp. 290-296.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1080/10286020.2011.554828
UR - https://doi.org/10.1080/10286020.2011.554828
TI - Synthesis and biological evaluation of bilobol and adipostatin A
T2 - Journal of Asian Natural Products Research
AU - Tanaka, Ayano
AU - Arai, Yasuhiro
AU - Kim, Su-Nam
AU - HAM, JUNGYEOB
AU - Usuki, Toyonobu
PY - 2011
DA - 2011/04/01
PB - Taylor & Francis
SP - 290-296
IS - 4
VL - 13
PMID - 21462031
SN - 1028-6020
SN - 1477-2213
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2011_Tanaka,
author = {Ayano Tanaka and Yasuhiro Arai and Su-Nam Kim and JUNGYEOB HAM and Toyonobu Usuki},
title = {Synthesis and biological evaluation of bilobol and adipostatin A},
journal = {Journal of Asian Natural Products Research},
year = {2011},
volume = {13},
publisher = {Taylor & Francis},
month = {apr},
url = {https://doi.org/10.1080/10286020.2011.554828},
number = {4},
pages = {290--296},
doi = {10.1080/10286020.2011.554828}
}
Cite this
MLA
Copy
Tanaka, Ayano, et al. “Synthesis and biological evaluation of bilobol and adipostatin A.” Journal of Asian Natural Products Research, vol. 13, no. 4, Apr. 2011, pp. 290-296. https://doi.org/10.1080/10286020.2011.554828.