Open Access
PLIP 2025: introducing protein–protein interactions to the protein–ligand interaction profiler
Тип публикации: Journal Article
Дата публикации: 2025-05-10
SCImago Q1
Tоп 10% SCImago
WOS Q1
БС1
SJR: 8.111
CiteScore: 29.8
Impact factor: 15
ISSN: 03051048, 13624962
Краткое описание
PLIP, the protein–ligand interaction profiler, analyses molecular interactions in protein structures. PLIP detects eight types of non-covalent interactions. Initially focused on small-molecule, DNA, and RNA interactions to a protein, the current release incorporates protein–protein interactions. We document the usefulness of this feature by comparing PLIP interactions of the cancer drug venetoclax with the native protein–protein interaction of Bcl-2 and BAX. PLIP reveals how the drug mimics the native interaction, as there is critical overlap in the interaction profiles. PLIP is available as a web server, source code with containers, and Jupyter notebook. The PLIP web server is online at https://plip-tool.biotec.tu-dresden.de.
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Метрики
216
Всего цитирований:
216
Цитирований c 2025:
213
(100%)
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MLA
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ГОСТ
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Schake P. et al. PLIP 2025: introducing protein–protein interactions to the protein–ligand interaction profiler // Nucleic Acids Research. 2025. Vol. 53. No. W1. p. W463-W465.
ГОСТ со всеми авторами (до 50)
Скопировать
Schake P., Bolz S. N., Linnemann K., Schroeder M. PLIP 2025: introducing protein–protein interactions to the protein–ligand interaction profiler // Nucleic Acids Research. 2025. Vol. 53. No. W1. p. W463-W465.
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RIS
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TY - JOUR
DO - 10.1093/nar/gkaf361
UR - https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkaf361/8128215
TI - PLIP 2025: introducing protein–protein interactions to the protein–ligand interaction profiler
T2 - Nucleic Acids Research
AU - Schake, Philipp
AU - Bolz, Sarah Naomi
AU - Linnemann, Katja
AU - Schroeder, Michael
PY - 2025
DA - 2025/05/10
PB - Oxford University Press
SP - W463-W465
IS - W1
VL - 53
SN - 0305-1048
SN - 1362-4962
ER -
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BibTex (до 50 авторов)
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@article{2025_Schake,
author = {Philipp Schake and Sarah Naomi Bolz and Katja Linnemann and Michael Schroeder},
title = {PLIP 2025: introducing protein–protein interactions to the protein–ligand interaction profiler},
journal = {Nucleic Acids Research},
year = {2025},
volume = {53},
publisher = {Oxford University Press},
month = {may},
url = {https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkaf361/8128215},
number = {W1},
pages = {W463--W465},
doi = {10.1093/nar/gkaf361}
}
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MLA
Скопировать
Schake, Philipp, et al. “PLIP 2025: introducing protein–protein interactions to the protein–ligand interaction profiler.” Nucleic Acids Research, vol. 53, no. W1, May. 2025, pp. W463-W465. https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkaf361/8128215.
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