Open Access
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volume 35 issue Web Server pages W407-W410

ProSA-web: interactive web service for the recognition of errors in three-dimensional structures of proteins

Publication typeJournal Article
Publication date2007-05-08
scimago Q1
wos Q1
SJR7.776
CiteScore31.7
Impact factor13.1
ISSN03051048, 13624962
PubMed ID:  17517781
Genetics
Abstract
A major problem in structural biology is the recognition of errors in experimental and theoretical models of protein structures. The ProSA program (Protein Structure Analysis) is an established tool which has a large user base and is frequently employed in the refinement and validation of experimental protein structures and in structure prediction and modeling. The analysis of protein structures is generally a difficult and cumbersome exercise. The new service presented here is a straightforward and easy to use extension of the classic ProSA program which exploits the advantages of interactive web-based applications for the display of scores and energy plots that highlight potential problems spotted in protein structures. In particular, the quality scores of a protein are displayed in the context of all known protein structures and problematic parts of a structure are shown and highlighted in a 3D molecule viewer. The service specifically addresses the needs encountered in the validation of protein structures obtained from X-ray analysis, NMR spectroscopy and theoretical calculations. ProSA-web is accessible at https://prosa.services.came.sbg.ac.at.
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GOST |
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GOST Copy
Wiederstein M., Sippl M. J. ProSA-web: interactive web service for the recognition of errors in three-dimensional structures of proteins // Nucleic Acids Research. 2007. Vol. 35. No. Web Server. p. W407-W410.
GOST all authors (up to 50) Copy
Wiederstein M., Sippl M. J. ProSA-web: interactive web service for the recognition of errors in three-dimensional structures of proteins // Nucleic Acids Research. 2007. Vol. 35. No. Web Server. p. W407-W410.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1093/nar/gkm290
UR - https://doi.org/10.1093/nar/gkm290
TI - ProSA-web: interactive web service for the recognition of errors in three-dimensional structures of proteins
T2 - Nucleic Acids Research
AU - Wiederstein, M.
AU - Sippl, M. J.
PY - 2007
DA - 2007/05/08
PB - Oxford University Press
SP - W407-W410
IS - Web Server
VL - 35
PMID - 17517781
SN - 0305-1048
SN - 1362-4962
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2007_Wiederstein,
author = {M. Wiederstein and M. J. Sippl},
title = {ProSA-web: interactive web service for the recognition of errors in three-dimensional structures of proteins},
journal = {Nucleic Acids Research},
year = {2007},
volume = {35},
publisher = {Oxford University Press},
month = {may},
url = {https://doi.org/10.1093/nar/gkm290},
number = {Web Server},
pages = {W407--W410},
doi = {10.1093/nar/gkm290}
}
MLA
Cite this
MLA Copy
Wiederstein, M., and M. J. Sippl. “ProSA-web: interactive web service for the recognition of errors in three-dimensional structures of proteins.” Nucleic Acids Research, vol. 35, no. Web Server, May. 2007, pp. W407-W410. https://doi.org/10.1093/nar/gkm290.