A first-in-human phase 0 clinical study of RNA interference–based spherical nucleic acids in patients with recurrent glioblastoma
Erin Dunbar
1
,
Caroline H Ko
2
,
T. Paunesku
3
,
Karan S. Dixit
1
,
Adam M. Sonabend
4
,
Orin Bloch
4
,
Matthew Tate
4
,
Margaret Schwartz
1
,
Laura Zuckerman
1
,
Ray Lezon
1
,
Rimas V. Lukas
1
,
Borko Jovanovic
5
,
Kathleen Mccortney
4
,
Howard Colman
6
,
Si Chen
7
,
Barry Lai
7
,
Olga Antipova
7
,
Junjing Deng
7
,
Luxi Li
7
,
Serena Tommasini-Ghelfi
1
,
Lisa Hurley
1
,
Dusten Unruh
4
,
Nitya V Sharma
8
,
Manoj Kandpal
9
,
Fotini M. Kouri
1
,
Ramana V. Davuluri
9
,
Daniel J. Brat
8
,
Miguel Muzzio
10
,
Mitchell Glass
11
,
Vinod Vijayakumar
11
,
Jeremy Heidel
12
,
F.J. Giles
13
,
Ann K Adams
14
,
C. David James
4
,
GAYLE E. WOLOSCHAK
3
,
Craig Horbinski
4, 8
,
Alexander H. Stegh
1, 2
7
10
Life Sciences Group, IIT Research Institute, Chicago, IL 60616, USA.
|
11
Broom Street Associates, Wilmington, DE 19806, USA.
|
12
Informulate LLC, Madison, WI 53704, USA.
|
Тип публикации: Journal Article
Дата публикации: 2021-03-10
scimago Q1
wos Q1
БС1
SJR: 6.722
CiteScore: 27.9
Impact factor: 14.6
ISSN: 19466234, 19466242
PubMed ID:
33692132
General Medicine
Краткое описание
RNA interference–based spherical nucleic acid nanoconjugates are a potentially safe and brain-penetrant approach for glioblastoma treatment.
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ГОСТ |
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ГОСТ
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Dunbar E. et al. A first-in-human phase 0 clinical study of RNA interference–based spherical nucleic acids in patients with recurrent glioblastoma // Science Translational Medicine. 2021. Vol. 13. No. 584.
ГОСТ со всеми авторами (до 50)
Скопировать
Dunbar E., Ko C. H., Paunesku T., Dixit K. S., Sonabend A. M., Bloch O., Tate M., Schwartz M., Zuckerman L., Lezon R., Lukas R. V., Jovanovic B., Mccortney K., Colman H., Chen S., Lai B., Antipova O., Deng J., Li L., Tommasini-Ghelfi S., Hurley L., Unruh D., Sharma N. V., Kandpal M., Kouri F. M., Davuluri R. V., Brat D. J., Muzzio M., Glass M., Vijayakumar V., Heidel J., Giles F., Adams A. K., James C. D., WOLOSCHAK G. E., Horbinski C., Stegh A. H. A first-in-human phase 0 clinical study of RNA interference–based spherical nucleic acids in patients with recurrent glioblastoma // Science Translational Medicine. 2021. Vol. 13. No. 584.
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RIS
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TY - JOUR
DO - 10.1126/scitranslmed.abb3945
UR - https://doi.org/10.1126/scitranslmed.abb3945
TI - A first-in-human phase 0 clinical study of RNA interference–based spherical nucleic acids in patients with recurrent glioblastoma
T2 - Science Translational Medicine
AU - Dunbar, Erin
AU - Ko, Caroline H
AU - Paunesku, T.
AU - Dixit, Karan S.
AU - Sonabend, Adam M.
AU - Bloch, Orin
AU - Tate, Matthew
AU - Schwartz, Margaret
AU - Zuckerman, Laura
AU - Lezon, Ray
AU - Lukas, Rimas V.
AU - Jovanovic, Borko
AU - Mccortney, Kathleen
AU - Colman, Howard
AU - Chen, Si
AU - Lai, Barry
AU - Antipova, Olga
AU - Deng, Junjing
AU - Li, Luxi
AU - Tommasini-Ghelfi, Serena
AU - Hurley, Lisa
AU - Unruh, Dusten
AU - Sharma, Nitya V
AU - Kandpal, Manoj
AU - Kouri, Fotini M.
AU - Davuluri, Ramana V.
AU - Brat, Daniel J.
AU - Muzzio, Miguel
AU - Glass, Mitchell
AU - Vijayakumar, Vinod
AU - Heidel, Jeremy
AU - Giles, F.J.
AU - Adams, Ann K
AU - James, C. David
AU - WOLOSCHAK, GAYLE E.
AU - Horbinski, Craig
AU - Stegh, Alexander H.
PY - 2021
DA - 2021/03/10
PB - American Association for the Advancement of Science (AAAS)
IS - 584
VL - 13
PMID - 33692132
SN - 1946-6234
SN - 1946-6242
ER -
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BibTex (до 50 авторов)
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@article{2021_Dunbar,
author = {Erin Dunbar and Caroline H Ko and T. Paunesku and Karan S. Dixit and Adam M. Sonabend and Orin Bloch and Matthew Tate and Margaret Schwartz and Laura Zuckerman and Ray Lezon and Rimas V. Lukas and Borko Jovanovic and Kathleen Mccortney and Howard Colman and Si Chen and Barry Lai and Olga Antipova and Junjing Deng and Luxi Li and Serena Tommasini-Ghelfi and Lisa Hurley and Dusten Unruh and Nitya V Sharma and Manoj Kandpal and Fotini M. Kouri and Ramana V. Davuluri and Daniel J. Brat and Miguel Muzzio and Mitchell Glass and Vinod Vijayakumar and Jeremy Heidel and F.J. Giles and Ann K Adams and C. David James and GAYLE E. WOLOSCHAK and Craig Horbinski and Alexander H. Stegh},
title = {A first-in-human phase 0 clinical study of RNA interference–based spherical nucleic acids in patients with recurrent glioblastoma},
journal = {Science Translational Medicine},
year = {2021},
volume = {13},
publisher = {American Association for the Advancement of Science (AAAS)},
month = {mar},
url = {https://doi.org/10.1126/scitranslmed.abb3945},
number = {584},
doi = {10.1126/scitranslmed.abb3945}
}