Open Access
Organic synthesis in a modular robotic system driven by a chemical programming language
Publication type: Journal Article
Publication date: 2019-01-11
scimago Q1
wos Q1
SJR: 10.416
CiteScore: 48.4
Impact factor: 45.8
ISSN: 00368075, 10959203
PubMed ID:
30498165
Multidisciplinary
Abstract
Clear directions for a robotic platform
The chemistry literature contains more than a century's worth of instructions for making molecules, all written by and for humans. Steiner et al. developed an autonomous compiler and robotic laboratory platform to synthesize organic compounds on the basis of standardized methods descriptions (see the Perspective by Milo). The platform comprises conventional equipment such as round-bottom flasks, separatory funnels, and a rotary evaporator to maximize its compatibility with extant literature. The authors showcase the system with short syntheses of three common pharmaceuticals that proceeded comparably to manual synthesis.
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Metrics
506
Total citations:
506
Citations from 2025:
106
(20.99%)
Cite this
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GOST
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Steiner S. et al. Organic synthesis in a modular robotic system driven by a chemical programming language // Science. 2019. Vol. 363. No. 6423.
GOST all authors (up to 50)
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Steiner S., Wolf J., Glatzel S., Andreou A., Granda J. M., Keenan G., Hinkley T., Aragon Camarasa G., Martin E., Angelone D., Cronin L. Organic synthesis in a modular robotic system driven by a chemical programming language // Science. 2019. Vol. 363. No. 6423.
Cite this
RIS
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TY - JOUR
DO - 10.1126/science.aav2211
UR - https://doi.org/10.1126/science.aav2211
TI - Organic synthesis in a modular robotic system driven by a chemical programming language
T2 - Science
AU - Steiner, Sebastian
AU - Wolf, Jakob
AU - Glatzel, Stefan
AU - Andreou, Anna
AU - Granda, Jarosław M
AU - Keenan, Graham
AU - Hinkley, Trevor
AU - Aragon Camarasa, Gerardo
AU - Martin, E.B.
AU - Angelone, D
AU - Cronin, Leroy
PY - 2019
DA - 2019/01/11
PB - American Association for the Advancement of Science (AAAS)
IS - 6423
VL - 363
PMID - 30498165
SN - 0036-8075
SN - 1095-9203
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2019_Steiner,
author = {Sebastian Steiner and Jakob Wolf and Stefan Glatzel and Anna Andreou and Jarosław M Granda and Graham Keenan and Trevor Hinkley and Gerardo Aragon Camarasa and E.B. Martin and D Angelone and Leroy Cronin},
title = {Organic synthesis in a modular robotic system driven by a chemical programming language},
journal = {Science},
year = {2019},
volume = {363},
publisher = {American Association for the Advancement of Science (AAAS)},
month = {jan},
url = {https://doi.org/10.1126/science.aav2211},
number = {6423},
doi = {10.1126/science.aav2211}
}