Compatibility of cells of the nervous system with structured biodegradable chitosan-based hydrogel matrices
Тип публикации: Journal Article
Дата публикации: 2016-09-09
scimago Q3
wos Q4
БС2
SJR: 0.294
CiteScore: 1.7
Impact factor: 1.1
ISSN: 00036838, 16083024
Biochemistry
Applied Microbiology and Biotechnology
Краткое описание
Hydrogel matrices for cell cultivation have been generated by two-photon laser polymerization of unsaturated chitosan derivatives and methacrylated hyaluronic acid. The adhesive and toxic properties of the matrices have been assessed, and the matrices have been shown to have a good compatibility with primary hippocampal cell cultures. The formation of morphologically normal neural networks by cells of the nervous system cultured on the surface of hydrogel matrices has been observed. The metabolic status of dissociated hippocampal cells cultured on the matrices was similar to that of the control cultures, as shown by the results of MTT reductase activity assay. Thus, matrices based on unsaturated polysaccharide derivatives crosslinked by laser irradiation showed good compatibility with differentiated cells of the nervous system and considerable potential for use in neurotransplantation.
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Timashev P. S. et al. Compatibility of cells of the nervous system with structured biodegradable chitosan-based hydrogel matrices // Applied Biochemistry and Microbiology. 2016. Vol. 52. No. 5. pp. 508-514.
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Timashev P. S., Bardakova K. N., Minaev N. V., Demina T. S., Mishchenko T. A., Mitroshina E. V., Akovantseva A. A., Koroleva A. V., Asyutin D. S., Pimenova L. F., Konovalov N. A., Akopova T. A., Solov'eva A., Mukhina I., Vedunova M. V., Chichkov B. N., Bagratashvili V. N. Compatibility of cells of the nervous system with structured biodegradable chitosan-based hydrogel matrices // Applied Biochemistry and Microbiology. 2016. Vol. 52. No. 5. pp. 508-514.
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TY - JOUR
DO - 10.1134/S0003683816050161
UR - https://doi.org/10.1134/S0003683816050161
TI - Compatibility of cells of the nervous system with structured biodegradable chitosan-based hydrogel matrices
T2 - Applied Biochemistry and Microbiology
AU - Timashev, P S
AU - Bardakova, K N
AU - Minaev, N V
AU - Demina, T S
AU - Mishchenko, T A
AU - Mitroshina, E V
AU - Akovantseva, A A
AU - Koroleva, A V
AU - Asyutin, D S
AU - Pimenova, L F
AU - Konovalov, N A
AU - Akopova, T A
AU - Solov'eva, A.B.
AU - Mukhina, I.V.
AU - Vedunova, M V
AU - Chichkov, B N
AU - Bagratashvili, V. N.
PY - 2016
DA - 2016/09/09
PB - Pleiades Publishing
SP - 508-514
IS - 5
VL - 52
SN - 0003-6838
SN - 1608-3024
ER -
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@article{2016_Timashev,
author = {P S Timashev and K N Bardakova and N V Minaev and T S Demina and T A Mishchenko and E V Mitroshina and A A Akovantseva and A V Koroleva and D S Asyutin and L F Pimenova and N A Konovalov and T A Akopova and A.B. Solov'eva and I.V. Mukhina and M V Vedunova and B N Chichkov and V. N. Bagratashvili},
title = {Compatibility of cells of the nervous system with structured biodegradable chitosan-based hydrogel matrices},
journal = {Applied Biochemistry and Microbiology},
year = {2016},
volume = {52},
publisher = {Pleiades Publishing},
month = {sep},
url = {https://doi.org/10.1134/S0003683816050161},
number = {5},
pages = {508--514},
doi = {10.1134/S0003683816050161}
}
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MLA
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Timashev, P. S., et al. “Compatibility of cells of the nervous system with structured biodegradable chitosan-based hydrogel matrices.” Applied Biochemistry and Microbiology, vol. 52, no. 5, Sep. 2016, pp. 508-514. https://doi.org/10.1134/S0003683816050161.