Synthesis and Antimicrobial and Antifungal Activity of Resin Acid Acetylene Derivatives
Publication type: Journal Article
Publication date: 2019-11-01
scimago Q4
wos Q3
SJR: 0.267
CiteScore: 1.9
Impact factor: 1.7
ISSN: 10681620, 1608330X, 15739163
Organic Chemistry
Biochemistry
Abstract
A series of diterpenes that contain the morpholine, pyrrolidine, benzyl, nitrophenyl, and 1,2,3-tetrazole heterocyclic fragments have been synthesized from acetylene derivatives of abietic, 7-formylabietic, dehydroabietic, maleopimaric, and dihydroquinopimaric acids. The antibacterial activity of the synthesized compounds against microorganisms and pathogenic fungi has been studied, and the primary assessment of their cytotoxicity and hemolytic activity has have been carried out. It has been found that the acetylene derivatives of abietic and dehydroabietic acids that contain the pyrrolidine substituent can effectively inhibit the growth of fungi Candida albicans and Cryptococcus neoformans, and their low hemolytic ability has been shown.
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Citations from 2024:
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Tretyakova E. V., Salimova E. V., Parfenova L. V. Synthesis and Antimicrobial and Antifungal Activity of Resin Acid Acetylene Derivatives // Russian Journal of Bioorganic Chemistry. 2019. Vol. 45. No. 6. pp. 545-551.
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Tretyakova E. V., Salimova E. V., Parfenova L. V. Synthesis and Antimicrobial and Antifungal Activity of Resin Acid Acetylene Derivatives // Russian Journal of Bioorganic Chemistry. 2019. Vol. 45. No. 6. pp. 545-551.
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RIS
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TY - JOUR
DO - 10.1134/S1068162019050121
UR - https://doi.org/10.1134/S1068162019050121
TI - Synthesis and Antimicrobial and Antifungal Activity of Resin Acid Acetylene Derivatives
T2 - Russian Journal of Bioorganic Chemistry
AU - Tretyakova, E V
AU - Salimova, E V
AU - Parfenova, L V
PY - 2019
DA - 2019/11/01
PB - Pleiades Publishing
SP - 545-551
IS - 6
VL - 45
SN - 1068-1620
SN - 1608-330X
SN - 1573-9163
ER -
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BibTex (up to 50 authors)
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@article{2019_Tretyakova,
author = {E V Tretyakova and E V Salimova and L V Parfenova},
title = {Synthesis and Antimicrobial and Antifungal Activity of Resin Acid Acetylene Derivatives},
journal = {Russian Journal of Bioorganic Chemistry},
year = {2019},
volume = {45},
publisher = {Pleiades Publishing},
month = {nov},
url = {https://doi.org/10.1134/S1068162019050121},
number = {6},
pages = {545--551},
doi = {10.1134/S1068162019050121}
}
Cite this
MLA
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Tretyakova, E. V., et al. “Synthesis and Antimicrobial and Antifungal Activity of Resin Acid Acetylene Derivatives.” Russian Journal of Bioorganic Chemistry, vol. 45, no. 6, Nov. 2019, pp. 545-551. https://doi.org/10.1134/S1068162019050121.
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