α-Thioureidoalkylation of functionally substituted ureas: I. Tandem cyclization and esterification in reactions of N-(carboxyalkyl)ureas with 1,3-dialkyl-4,5-dihydroxy-4,5-diphenylimidazolidine-2-thiones in alcohols
Тип публикации: Journal Article
Дата публикации: 2011-10-01
scimago Q4
wos Q4
БС3
SJR: 0.190
CiteScore: 1.3
Impact factor: 0.9
ISSN: 10704280, 16083393
Organic Chemistry
Краткое описание
Acid-catalyzed reactions of N-(carboxyalkyl)ureas with 1,3-dialkyl-4,5-dihydroxy-4,5-diphenylimidazolidine-2-thiones in methanol or propan-2-ol led to the formation of previously unknown ω-(4,6-dialkyl-2-oxo-3a,6a-diphenyl-5-thioxooctahydroimidazo[4,5-d]imidazol-1-yl)alkanoic acids and their methyl and isopropyl esters. The structure of some esters was proved by X-ray analysis. Methyl (4,6-diethyl-2-oxo-3a,6adiphenyl-5-thioxooctahydroimidazo[4,5-d]imidazol-1-yl)acetate showed anxiolytic effect.
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Baranov V. et al. α-Thioureidoalkylation of functionally substituted ureas: I. Tandem cyclization and esterification in reactions of N-(carboxyalkyl)ureas with 1,3-dialkyl-4,5-dihydroxy-4,5-diphenylimidazolidine-2-thiones in alcohols // Russian Journal of Organic Chemistry. 2011. Vol. 47. No. 10. pp. 1564-1571.
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Baranov V., Gazieva G. A., Nelyubina Yu. V., Kravchenko A. N., Makhova N. N. α-Thioureidoalkylation of functionally substituted ureas: I. Tandem cyclization and esterification in reactions of N-(carboxyalkyl)ureas with 1,3-dialkyl-4,5-dihydroxy-4,5-diphenylimidazolidine-2-thiones in alcohols // Russian Journal of Organic Chemistry. 2011. Vol. 47. No. 10. pp. 1564-1571.
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TY - JOUR
DO - 10.1134/S1070428011100204
UR - http://link.springer.com/10.1134/S1070428011100204
TI - α-Thioureidoalkylation of functionally substituted ureas: I. Tandem cyclization and esterification in reactions of N-(carboxyalkyl)ureas with 1,3-dialkyl-4,5-dihydroxy-4,5-diphenylimidazolidine-2-thiones in alcohols
T2 - Russian Journal of Organic Chemistry
AU - Baranov, V.V.
AU - Gazieva, G A
AU - Nelyubina, Yu V
AU - Kravchenko, A N
AU - Makhova, N N
PY - 2011
DA - 2011/10/01
PB - Pleiades Publishing
SP - 1564-1571
IS - 10
VL - 47
SN - 1070-4280
SN - 1608-3393
ER -
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@article{2011_Baranov,
author = {V.V. Baranov and G A Gazieva and Yu V Nelyubina and A N Kravchenko and N N Makhova},
title = {α-Thioureidoalkylation of functionally substituted ureas: I. Tandem cyclization and esterification in reactions of N-(carboxyalkyl)ureas with 1,3-dialkyl-4,5-dihydroxy-4,5-diphenylimidazolidine-2-thiones in alcohols},
journal = {Russian Journal of Organic Chemistry},
year = {2011},
volume = {47},
publisher = {Pleiades Publishing},
month = {oct},
url = {http://link.springer.com/10.1134/S1070428011100204},
number = {10},
pages = {1564--1571},
doi = {10.1134/S1070428011100204}
}
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Baranov, V.V., et al. “α-Thioureidoalkylation of functionally substituted ureas: I. Tandem cyclization and esterification in reactions of N-(carboxyalkyl)ureas with 1,3-dialkyl-4,5-dihydroxy-4,5-diphenylimidazolidine-2-thiones in alcohols.” Russian Journal of Organic Chemistry, vol. 47, no. 10, Oct. 2011, pp. 1564-1571. http://link.springer.com/10.1134/S1070428011100204.