Glass Physics and Chemistry

, том 37 , издание 1 , страницы 78-84

Synthesis and study of antimicrobial activity of bioconjugates of silver nanoparticles and endogenous antibiotics

O Yu Golubeva ¹

O V Shamova ²

D S Orlov ²

T Yu Pazina ²

A S Boldina ¹

I A Drozdova ¹

V. N. Kokryakov ²

Скрыть аффилиации авторов Показать аффилиации авторов: 2 аффилиации

Grebenshchikov Institute of Silicate Chemistry, Russian Academy of Sciences, St. Petersburg, Russia |

Institute of Experimental Medicine, North-Western Branch, Russian Academy of Medical Sciences, St. Petersburg, Russia |

Тип публикации: Journal Article

Дата публикации: 2011-02-01

Pleiades Publishing

Glass Physics and Chemistry

scimago Q4

wos Q4

БС2

SJR: 0.200

CiteScore: 1.2

Impact factor: 0.6

ISSN: 10876596, 1608313X

DOI: 10.1134/S1087659611010056

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Materials Chemistry

Ceramics and Composites

Condensed Matter Physics

Краткое описание

Bioconjugates of silver nanoparticles and antimicrobial peptides of the bactenecin family, which are endogenous antibiotics, have been synthesized. The biological activity of the prepared bioconjugates has been evaluated. It has been established that the conjugates of silver nanoparticles with the peptide G-Bac3.4 exhibit an antimicrobial activity, including the activity with respect to the strain Pseudomonas aeruginosa resistant to traditional antibiotics and the strain Staphylococcus aureus (MRSA ATCC 33591) resistant to methicillin. It has been demonstrated that the complexes of silver nanoparticles with antimicrobial peptides do not possess a pronounced membranolytic effect inherent in peptides. The results obtained have made it possible to draw the conclusion that the properties of the synthesized conjugates differ from those characteristic of constituting peptides and silver nanoparticles.

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Golubeva O. Yu. et al. Synthesis and study of antimicrobial activity of bioconjugates of silver nanoparticles and endogenous antibiotics // Glass Physics and Chemistry. 2011. Vol. 37. No. 1. pp. 78-84.

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Golubeva O. Yu., Shamova O. V., Orlov D. S., Pazina T. Yu., Boldina A. S., Drozdova I. A., Kokryakov V. N. Synthesis and study of antimicrobial activity of bioconjugates of silver nanoparticles and endogenous antibiotics // Glass Physics and Chemistry. 2011. Vol. 37. No. 1. pp. 78-84.

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TY - JOUR

DO - 10.1134/S1087659611010056

UR - https://doi.org/10.1134/S1087659611010056

TI - Synthesis and study of antimicrobial activity of bioconjugates of silver nanoparticles and endogenous antibiotics

T2 - Glass Physics and Chemistry

AU - Golubeva, O Yu

AU - Shamova, O V

AU - Orlov, D S

AU - Pazina, T Yu

AU - Boldina, A S

AU - Drozdova, I A

AU - Kokryakov, V. N.

PY - 2011

DA - 2011/02/01

PB - Pleiades Publishing

SP - 78-84

IS - 1

VL - 37

SN - 1087-6596

SN - 1608-313X

ER -

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@article{2011_Golubeva,

author = {O Yu Golubeva and O V Shamova and D S Orlov and T Yu Pazina and A S Boldina and I A Drozdova and V. N. Kokryakov},

title = {Synthesis and study of antimicrobial activity of bioconjugates of silver nanoparticles and endogenous antibiotics},

journal = {Glass Physics and Chemistry},

year = {2011},

volume = {37},

publisher = {Pleiades Publishing},

month = {feb},

url = {https://doi.org/10.1134/S1087659611010056},

number = {1},

pages = {78--84},

doi = {10.1134/S1087659611010056}

}

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Golubeva, O. Yu., et al. “Synthesis and study of antimicrobial activity of bioconjugates of silver nanoparticles and endogenous antibiotics.” Glass Physics and Chemistry, vol. 37, no. 1, Feb. 2011, pp. 78-84. https://doi.org/10.1134/S1087659611010056.