Glass Physics and Chemistry

, volume 37 , issue 1 , pages 78-84

Synthesis and study of antimicrobial activity of bioconjugates of silver nanoparticles and endogenous antibiotics

O Yu Golubeva ¹

O V Shamova ²

D S Orlov ²

T Yu Pazina ²

A S Boldina ¹

I A Drozdova ¹

V. N. Kokryakov ²

Hide authors affiliations Show authors affiliations: 2 affiliations

Grebenshchikov Institute of Silicate Chemistry, Russian Academy of Sciences, St. Petersburg, Russia |

Institute of Experimental Medicine, North-Western Branch, Russian Academy of Medical Sciences, St. Petersburg, Russia |

Publication type: Journal Article

Publication date: 2011-02-01

Pleiades Publishing

Glass Physics and Chemistry

scimago Q4

wos Q4

SJR: 0.200

CiteScore: 1.2

Impact factor: 0.6

ISSN: 10876596, 1608313X

DOI: 10.1134/S1087659611010056

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Materials Chemistry

Ceramics and Composites

Condensed Matter Physics

Abstract

Bioconjugates of silver nanoparticles and antimicrobial peptides of the bactenecin family, which are endogenous antibiotics, have been synthesized. The biological activity of the prepared bioconjugates has been evaluated. It has been established that the conjugates of silver nanoparticles with the peptide G-Bac3.4 exhibit an antimicrobial activity, including the activity with respect to the strain Pseudomonas aeruginosa resistant to traditional antibiotics and the strain Staphylococcus aureus (MRSA ATCC 33591) resistant to methicillin. It has been demonstrated that the complexes of silver nanoparticles with antimicrobial peptides do not possess a pronounced membranolytic effect inherent in peptides. The results obtained have made it possible to draw the conclusion that the properties of the synthesized conjugates differ from those characteristic of constituting peptides and silver nanoparticles.

Found

5 citations

Golubeva Olga

DSc in Chemistry

83 publications, 883 citations, 20 reviews

h-index: 15

I. V. Grebenshchikov Institute of Silicate Chemistry of NRC «Kurchatov Institute»

Research interests

Silicates

Zeolites

1 citation

Vlasov Roman

4 publications, 21 citations

h-index: 2

Kazan Federal University

Research interests

Condensed matter physics

Molecular dynamics

Phase transitions

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Golubeva O. Yu. et al. Synthesis and study of antimicrobial activity of bioconjugates of silver nanoparticles and endogenous antibiotics // Glass Physics and Chemistry. 2011. Vol. 37. No. 1. pp. 78-84.

GOST all authors (up to 50) Copy

Golubeva O. Yu., Shamova O. V., Orlov D. S., Pazina T. Yu., Boldina A. S., Drozdova I. A., Kokryakov V. N. Synthesis and study of antimicrobial activity of bioconjugates of silver nanoparticles and endogenous antibiotics // Glass Physics and Chemistry. 2011. Vol. 37. No. 1. pp. 78-84.

RIS |

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RIS Copy

TY - JOUR

DO - 10.1134/S1087659611010056

UR - https://doi.org/10.1134/S1087659611010056

TI - Synthesis and study of antimicrobial activity of bioconjugates of silver nanoparticles and endogenous antibiotics

T2 - Glass Physics and Chemistry

AU - Golubeva, O Yu

AU - Shamova, O V

AU - Orlov, D S

AU - Pazina, T Yu

AU - Boldina, A S

AU - Drozdova, I A

AU - Kokryakov, V. N.

PY - 2011

DA - 2011/02/01

PB - Pleiades Publishing

SP - 78-84

IS - 1

VL - 37

SN - 1087-6596

SN - 1608-313X

ER -

BibTex |

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BibTex (up to 50 authors) Copy

@article{2011_Golubeva,

author = {O Yu Golubeva and O V Shamova and D S Orlov and T Yu Pazina and A S Boldina and I A Drozdova and V. N. Kokryakov},

title = {Synthesis and study of antimicrobial activity of bioconjugates of silver nanoparticles and endogenous antibiotics},

journal = {Glass Physics and Chemistry},

year = {2011},

volume = {37},

publisher = {Pleiades Publishing},

month = {feb},

url = {https://doi.org/10.1134/S1087659611010056},

number = {1},

pages = {78--84},

doi = {10.1134/S1087659611010056}

}

MLA

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MLA Copy

Golubeva, O. Yu., et al. “Synthesis and study of antimicrobial activity of bioconjugates of silver nanoparticles and endogenous antibiotics.” Glass Physics and Chemistry, vol. 37, no. 1, Feb. 2011, pp. 78-84. https://doi.org/10.1134/S1087659611010056.