Polymer Science - Series B

, volume 60 , issue 1 , pages 84-90

Biodegradable Electrostatic Complexes of Chitosan Cationic Microparticles and Anionic Liposomes

A. A. Efimova ¹

F D Mulashkin ¹

G N Rudenskaya ¹

E G Evtushenko ¹

V. N. Orlov ²

N.S. Melik-Nubarov ¹

G G Krivtsov ³

A A Yaroslavov ¹

Hide authors affiliations Show authors affiliations: 3 affiliations

Faculty of Chemistry, Moscow State University, Moscow, Russia |

Belozerskii Institute of Molecular Biology and Bioorganic Chemistry, Moscow State University, Moscow, Russia |

Mechnikov Research Institute of Vaccines and Sera, Moscow, Russia |

Publication type: Journal Article

Publication date: 2018-01-01

Pleiades Publishing

Polymer Science - Series B

scimago Q3

wos Q4

SJR: 0.234

CiteScore: 1.8

Impact factor: 1.0

ISSN: 15600904, 15556123

DOI: 10.1134/S1560090418010037

Copy DOI

Materials Chemistry

Ceramics and Composites

Polymers and Plastics

Abstract

Using the electrostatic adsorption of anionic liposomes on the surface of cationic microparticles of ion-crosslinked chitosan, complexes in which each microparticle can bind up to 110 intact (undestroyed) liposomes are prepared. The saturated complex 350–400 nm in diameter does not dissociate to initial components in aqueous solutions with pH 7 and a NaCl concentration of 0.15 mol/L, but decomposes to 10-nm particles in the presence of proteolytic enzymes. The chitosan–liposome complex and its biodegradation products are characterized by a low cytotoxicity. The described technique may be used to obtain biodegradable multiliposomal containers for the encapsulation and delivery of drugs.

Found

4 citations

Melik-Nubarov Nikolay

🥼

DSc in Chemistry

95 publications, 2 658 citations, 3 reviews

h-index: 25

Lomonosov Moscow State University

Research interests

Chemically induced photodynamic teramia

Drug delivery

High molecular weight compounds

Photodynamic Therapy (PDT)

Synthesis of amphiphilic biodegradable copolymers

Top-30

Journals

	1 2 3
Mendeleev Communications	Mendeleev Communications, 3, 23.08% Mendeleev Communications 3 publications, 23.08%
Colloids and Surfaces B: Biointerfaces	Colloids and Surfaces B: Biointerfaces, 2, 15.38% Colloids and Surfaces B: Biointerfaces 2 publications, 15.38%
International Journal of Biological Macromolecules	International Journal of Biological Macromolecules, 1, 7.69% International Journal of Biological Macromolecules 1 publication, 7.69%
Russian Journal of General Chemistry	Russian Journal of General Chemistry, 1, 7.69% Russian Journal of General Chemistry 1 publication, 7.69%
Polymer Science - Series A	Polymer Science - Series A, 1, 7.69% Polymer Science - Series A 1 publication, 7.69%
Pure and Applied Chemistry	Pure and Applied Chemistry, 1, 7.69% Pure and Applied Chemistry 1 publication, 7.69%
Journal of Food Measurement and Characterization	Journal of Food Measurement and Characterization, 1, 7.69% Journal of Food Measurement and Characterization 1 publication, 7.69%
Molecules	Molecules, 1, 7.69% Molecules 1 publication, 7.69%
Food Chemistry	Food Chemistry, 1, 7.69% Food Chemistry 1 publication, 7.69%
Pharmaceuticals	Pharmaceuticals, 1, 7.69% Pharmaceuticals 1 publication, 7.69%
	1 2 3

Publishers

	1 2 3 4
Elsevier	Elsevier, 4, 30.77% Elsevier 4 publications, 30.77%
OOO Zhurnal "Mendeleevskie Soobshcheniya"	OOO Zhurnal "Mendeleevskie Soobshcheniya", 3, 23.08% OOO Zhurnal "Mendeleevskie Soobshcheniya" 3 publications, 23.08%
Pleiades Publishing	Pleiades Publishing, 2, 15.38% Pleiades Publishing 2 publications, 15.38%
MDPI	MDPI, 2, 15.38% MDPI 2 publications, 15.38%
Walter de Gruyter	Walter de Gruyter, 1, 7.69% Walter de Gruyter 1 publication, 7.69%
Springer Nature	Springer Nature, 1, 7.69% Springer Nature 1 publication, 7.69%
	1 2 3 4

We do not take into account publications without a DOI.
Statistics recalculated weekly.

Are you a researcher?

Create a profile to get free access to personal recommendations for colleagues and new articles.

Metrics

Cite this

GOST |

Cite this

GOST Copy

Efimova A. A. et al. Biodegradable Electrostatic Complexes of Chitosan Cationic Microparticles and Anionic Liposomes // Polymer Science - Series B. 2018. Vol. 60. No. 1. pp. 84-90.

GOST all authors (up to 50) Copy

Efimova A. A., Mulashkin F. D., Rudenskaya G. N., Evtushenko E. G., Orlov V. N., Melik-Nubarov N., Krivtsov G. G., Yaroslavov A. A. Biodegradable Electrostatic Complexes of Chitosan Cationic Microparticles and Anionic Liposomes // Polymer Science - Series B. 2018. Vol. 60. No. 1. pp. 84-90.

RIS |

Cite this

RIS Copy

TY - JOUR

DO - 10.1134/S1560090418010037

UR - https://doi.org/10.1134/S1560090418010037

TI - Biodegradable Electrostatic Complexes of Chitosan Cationic Microparticles and Anionic Liposomes

T2 - Polymer Science - Series B

AU - Efimova, A. A.

AU - Mulashkin, F D

AU - Rudenskaya, G N

AU - Evtushenko, E G

AU - Orlov, V. N.

AU - Melik-Nubarov, N.S.

AU - Krivtsov, G G

AU - Yaroslavov, A A

PY - 2018

DA - 2018/01/01

PB - Pleiades Publishing

SP - 84-90

IS - 1

VL - 60

SN - 1560-0904

SN - 1555-6123

ER -

BibTex |

Cite this

BibTex (up to 50 authors) Copy

@article{2018_Efimova,

author = {A. A. Efimova and F D Mulashkin and G N Rudenskaya and E G Evtushenko and V. N. Orlov and N.S. Melik-Nubarov and G G Krivtsov and A A Yaroslavov},

title = {Biodegradable Electrostatic Complexes of Chitosan Cationic Microparticles and Anionic Liposomes},

journal = {Polymer Science - Series B},

year = {2018},

volume = {60},

publisher = {Pleiades Publishing},

month = {jan},

url = {https://doi.org/10.1134/S1560090418010037},

number = {1},

pages = {84--90},

doi = {10.1134/S1560090418010037}

}

MLA

Cite this

MLA Copy

Efimova, A. A., et al. “Biodegradable Electrostatic Complexes of Chitosan Cationic Microparticles and Anionic Liposomes.” Polymer Science - Series B, vol. 60, no. 1, Jan. 2018, pp. 84-90. https://doi.org/10.1134/S1560090418010037.