Biological and Pharmaceutical Bulletin, volume 24, issue 2, pages 159-162

Effects of Two Saponins Extracted from the Polygonatum Zanlanscianense Pamp on the Human Leukemia (HL-60) Cells.

Zhao Wang ¹

Jiangbing Zhou ¹

Yong Ju ²

Hongjun Zhang ¹

Mingjie Liu ¹

Xue Li ²

Show full list: 7 authors

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Department of Biological Science and Biotechnology, Tsinghua University |

Bioorganic Phosphorus Chemistry Laboratory, Tsinghua University |

Publication type: Journal Article

Publication date: 2002-08-26

Pharmaceutical Society of Japan

Journal: Biological and Pharmaceutical Bulletin

scimago Q2

SJR: 0.518

CiteScore: 3.5

Impact factor: 1.7

ISSN: 09186158, 13475215

DOI: 10.1248/bpb.24.159

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PubMed ID: 11217084

General Medicine

Pharmacology

Pharmaceutical Science

Abstract

Two saponins, methyl protodioscin and dioscin, were extracted from the root of Polygonatum Zanlanscianense Pamp. One of them, dioscin exerted significant inhibitory effects on the growth of the human leukemia cell HL-60, inducing differentiation and apoptosis. HL60 cells were induced mainly along the granulocytic lineage. In addition, we have found that dioscin affects many cancer cells. These studies may have important significance in treating related cancers.

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CITATIONS

98 Total citations

5 Recent citations

4.81 Field Citation Ratio

2.28 Relative Citation Ratio

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GOST |

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GOST Copy

Wang Z. et al. Effects of Two Saponins Extracted from the Polygonatum Zanlanscianense Pamp on the Human Leukemia (HL-60) Cells. // Biological and Pharmaceutical Bulletin. 2002. Vol. 24. No. 2. pp. 159-162.

GOST all authors (up to 50) Copy

Wang Z., Zhou J., Ju Y., Zhang H., Liu M., Li X., Li X. Effects of Two Saponins Extracted from the Polygonatum Zanlanscianense Pamp on the Human Leukemia (HL-60) Cells. // Biological and Pharmaceutical Bulletin. 2002. Vol. 24. No. 2. pp. 159-162.

RIS |

Cite this

RIS Copy

TY - JOUR

DO - 10.1248/bpb.24.159

UR - https://doi.org/10.1248/bpb.24.159

TI - Effects of Two Saponins Extracted from the Polygonatum Zanlanscianense Pamp on the Human Leukemia (HL-60) Cells.

T2 - Biological and Pharmaceutical Bulletin

AU - Wang, Zhao

AU - Zhou, Jiangbing

AU - Ju, Yong

AU - Zhang, Hongjun

AU - Liu, Mingjie

AU - Li, Xue

PY - 2002

DA - 2002/08/26

PB - Pharmaceutical Society of Japan

SP - 159-162

IS - 2

VL - 24

PMID - 11217084

SN - 0918-6158

SN - 1347-5215

ER -

BibTex |

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BibTex (up to 50 authors) Copy

@article{2002_Wang,

author = {Zhao Wang and Jiangbing Zhou and Yong Ju and Hongjun Zhang and Mingjie Liu and Xue Li and Xue Li},

title = {Effects of Two Saponins Extracted from the Polygonatum Zanlanscianense Pamp on the Human Leukemia (HL-60) Cells.},

journal = {Biological and Pharmaceutical Bulletin},

year = {2002},

volume = {24},

publisher = {Pharmaceutical Society of Japan},

month = {aug},

url = {https://doi.org/10.1248/bpb.24.159},

number = {2},

pages = {159--162},

doi = {10.1248/bpb.24.159}

}

MLA

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MLA Copy

Wang, Zhao, et al. “Effects of Two Saponins Extracted from the Polygonatum Zanlanscianense Pamp on the Human Leukemia (HL-60) Cells..” Biological and Pharmaceutical Bulletin, vol. 24, no. 2, Aug. 2002, pp. 159-162. https://doi.org/10.1248/bpb.24.159.

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Publisher

Pharmaceutical Society of Japan

Journal

Biological and Pharmaceutical Bulletin

scimago Q2

SJR

0.518

CiteScore

3.5

Impact factor

1.7

ISSN

09186158 (Print)

13475215 (Electronic)

Profiles

Li, Xue Qian