Open Access
Actinobacteria Isolated from an Underground Lake and Moonmilk Speleothem from the Biggest Conglomeratic Karstic Cave in Siberia as Sources of Novel Biologically Active Compounds
Denis V Axenov Gibanov
1
,
Irina V. Voytsekhovskaya
1
,
Bogdan T Tokovenko
2
,
Eugeniy S. Protasov
1
,
Stanislav V. Gamaiunov
1
,
Yuriy V Rebets
2
,
Andriy N Luzhetskyy
3
,
Maxim A. Timofeyev
1
Publication type: Journal Article
Publication date: 2016-02-22
scimago Q1
wos Q2
SJR: 0.803
CiteScore: 5.4
Impact factor: 2.6
ISSN: 19326203
PubMed ID:
26901168
Multidisciplinary
Abstract
Actinobacteria isolated from unstudied ecosystems are one of the most interesting and promising sources of novel biologically active compounds. Cave ecosystems are unusual and rarely studied. Here, we report the isolation and characterization of ten new actinobacteria strains isolated from an ancient underground lake and moonmilk speleothem from the biggest conglomeratic karstic cave in Siberia with a focus on the biological activity of the obtained strains and the metabolite dereplication of one active strain. Streptomyces genera isolates from moonmilk speleothem demonstrated antibacterial and antifungal activities. Some of the strains were able to inhibit the growth of pathogenic Candida albicans.
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52
Total citations:
52
Citations from 2024:
10
(19%)
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GOST
Copy
Axenov Gibanov D. V. et al. Actinobacteria Isolated from an Underground Lake and Moonmilk Speleothem from the Biggest Conglomeratic Karstic Cave in Siberia as Sources of Novel Biologically Active Compounds // PLoS ONE. 2016. Vol. 11. No. 2. p. e0149216.
GOST all authors (up to 50)
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Axenov Gibanov D. V., Voytsekhovskaya I. V., Tokovenko B. T., Protasov E. S., Gamaiunov S. V., Rebets Y. V., Luzhetskyy A. N., Timofeyev M. A. Actinobacteria Isolated from an Underground Lake and Moonmilk Speleothem from the Biggest Conglomeratic Karstic Cave in Siberia as Sources of Novel Biologically Active Compounds // PLoS ONE. 2016. Vol. 11. No. 2. p. e0149216.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1371/journal.pone.0149216
UR - https://doi.org/10.1371/journal.pone.0149216
TI - Actinobacteria Isolated from an Underground Lake and Moonmilk Speleothem from the Biggest Conglomeratic Karstic Cave in Siberia as Sources of Novel Biologically Active Compounds
T2 - PLoS ONE
AU - Axenov Gibanov, Denis V
AU - Voytsekhovskaya, Irina V.
AU - Tokovenko, Bogdan T
AU - Protasov, Eugeniy S.
AU - Gamaiunov, Stanislav V.
AU - Rebets, Yuriy V
AU - Luzhetskyy, Andriy N
AU - Timofeyev, Maxim A.
PY - 2016
DA - 2016/02/22
PB - Public Library of Science (PLoS)
SP - e0149216
IS - 2
VL - 11
PMID - 26901168
SN - 1932-6203
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2016_Axenov Gibanov,
author = {Denis V Axenov Gibanov and Irina V. Voytsekhovskaya and Bogdan T Tokovenko and Eugeniy S. Protasov and Stanislav V. Gamaiunov and Yuriy V Rebets and Andriy N Luzhetskyy and Maxim A. Timofeyev},
title = {Actinobacteria Isolated from an Underground Lake and Moonmilk Speleothem from the Biggest Conglomeratic Karstic Cave in Siberia as Sources of Novel Biologically Active Compounds},
journal = {PLoS ONE},
year = {2016},
volume = {11},
publisher = {Public Library of Science (PLoS)},
month = {feb},
url = {https://doi.org/10.1371/journal.pone.0149216},
number = {2},
pages = {e0149216},
doi = {10.1371/journal.pone.0149216}
}
Cite this
MLA
Copy
Axenov Gibanov, Denis V., et al. “Actinobacteria Isolated from an Underground Lake and Moonmilk Speleothem from the Biggest Conglomeratic Karstic Cave in Siberia as Sources of Novel Biologically Active Compounds.” PLoS ONE, vol. 11, no. 2, Feb. 2016, p. e0149216. https://doi.org/10.1371/journal.pone.0149216.
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