Hemicellulose from Plant Biomass in Medical and Pharmaceutical Application: A Critical Review
Background:
Due to the non-toxicity, abundance and biodegradability, recently more and more attention has been focused on the exploration of hemicellulose as the potential substrate for the production of liquid fuels and other value-added chemicals and materials in different fields. This review aims to summarize the current knowledge on the promising application of nature hemicellulose and its derivative products including its degradation products, its new derivatives and hemicellulosebased medical biodegradable materials in the medical and pharmaceutical field, especially for inmmune regulation, bacteria inhibition, drug release, anti-caries, scaffold materials and anti-tumor.
Methods:
We searched the related papers about the medical and pharmaceutical application of hemicellulose and its derivative products, and summarized their preparation methods, properties and use effects.
Results:
Two hundred and twenty-seven papers were included in this review. Forty-seven papers introduced the extraction and application in immune regulation of nature hemicellulose, such as xylan, mannan, xyloglucan (XG) and β-glucan. Seventy-seven papers mentioned the preparation and application of degradation products of hemicellulose for adjusting intestinal function, maintaining blood glucose levels, enhancing the immunity and alleviating human fatigue fields such as xylooligosaccharides, xylitol, xylose, arabinose, etc. The preparation of hemicellulose derivatives were described in thirty-two papers such as hemicellulose esters, hemicellulose ethers and their effects on anticoagulants, adsorption of creatinine, the addition of immune cells and the inhibition of harmful bacteria. Finally, the preparations of hemicellulose-based materials such as hydrogels and membrane for the field of drug release, cell immobilization, cancer therapy and wound dressings were presented using fifty-five papers.
Conclusion:
The structure of hemicellulose-based products has the significant impact on properties and the use effect for the immunity, and treating various diseases of human. However, some efforts should be made to explore and improve the properties of hemicellulose-based products and design the new materials to broaden hemicellulose applications.
Топ-30
Журналы
|
1
2
3
4
5
6
7
8
9
|
|
|
International Journal of Biological Macromolecules
9 публикаций, 10%
|
|
|
Polymers
7 публикаций, 7.78%
|
|
|
Biomass Conversion and Biorefinery
2 публикации, 2.22%
|
|
|
Carbohydrate Polymers
2 публикации, 2.22%
|
|
|
Industrial Crops and Products
2 публикации, 2.22%
|
|
|
Food Bioscience
2 публикации, 2.22%
|
|
|
ChemSusChem
2 публикации, 2.22%
|
|
|
Polymers for Advanced Technologies
2 публикации, 2.22%
|
|
|
RSC Sustainability
2 публикации, 2.22%
|
|
|
Russian Chemical Bulletin
2 публикации, 2.22%
|
|
|
Current Medicinal Chemistry
1 публикация, 1.11%
|
|
|
Acta Crystallographica Section F:Structural Biology Communications
1 публикация, 1.11%
|
|
|
Materials
1 публикация, 1.11%
|
|
|
Catalysts
1 публикация, 1.11%
|
|
|
Microorganisms
1 публикация, 1.11%
|
|
|
Sustainability
1 публикация, 1.11%
|
|
|
Frontiers in Nutrition
1 публикация, 1.11%
|
|
|
Energies
1 публикация, 1.11%
|
|
|
Food Science and Biotechnology
1 публикация, 1.11%
|
|
|
Progress in Polymer Science
1 публикация, 1.11%
|
|
|
Materials Letters
1 публикация, 1.11%
|
|
|
Colloids and Surfaces A: Physicochemical and Engineering Aspects
1 публикация, 1.11%
|
|
|
Ceramics International
1 публикация, 1.11%
|
|
|
Biocatalysis and Agricultural Biotechnology
1 публикация, 1.11%
|
|
|
Carbohydrate Research
1 публикация, 1.11%
|
|
|
Applied Catalysis B: Environmental
1 публикация, 1.11%
|
|
|
Renewable and Sustainable Energy Reviews
1 публикация, 1.11%
|
|
|
Macromolecular Bioscience
1 публикация, 1.11%
|
|
|
Journal of the Science of Food and Agriculture
1 публикация, 1.11%
|
|
|
1
2
3
4
5
6
7
8
9
|
Издатели
|
5
10
15
20
25
30
35
|
|
|
Elsevier
33 публикации, 36.67%
|
|
|
MDPI
15 публикаций, 16.67%
|
|
|
Springer Nature
13 публикаций, 14.44%
|
|
|
Wiley
11 публикаций, 12.22%
|
|
|
Royal Society of Chemistry (RSC)
5 публикаций, 5.56%
|
|
|
Taylor & Francis
2 публикации, 2.22%
|
|
|
Bentham Science Publishers Ltd.
1 публикация, 1.11%
|
|
|
International Union of Crystallography (IUCr)
1 публикация, 1.11%
|
|
|
Frontiers Media S.A.
1 публикация, 1.11%
|
|
|
Korean Society of Food Science and Technology
1 публикация, 1.11%
|
|
|
SAGE
1 публикация, 1.11%
|
|
|
IntechOpen
1 публикация, 1.11%
|
|
|
American Chemical Society (ACS)
1 публикация, 1.11%
|
|
|
Kalvis
1 публикация, 1.11%
|
|
|
American Society for Microbiology
1 публикация, 1.11%
|
|
|
5
10
15
20
25
30
35
|
- Мы не учитываем публикации, у которых нет DOI.
- Статистика публикаций обновляется еженедельно.