Open Access
Antioxidants, volume 10, issue 6, pages 863
Sagan Dalya Tea, a New “Old” Probable Adaptogenic Drug: Metabolic Characterization and Bioactivity Potentials of Rhododendron adamsii Leaves
Publication type: Journal Article
Publication date: 2021-05-27
Biochemistry
Molecular Biology
Cell Biology
Clinical Biochemistry
Physiology
Abstract
Adams’ rhododendron (Rhododendron adamsii Rehder) or Sagan Dalya tea is a famous Siberian evergreen medical plant of the Ericaceae family used in traditional medicines of Buryats, Yakuts, and Mongols as a tonic, stimulant, and adaptogenic drug. The high popularity of R. adamsii coupled with poor scientific knowledge prompted the addressing of gaps related to metabolic and biomedical data of Sagan Dalya tea. The application of solid-phase extraction and liquid chromatography-mass spectrometric techniques for the metabolomic study of R. adamsii leaf extracts resulted in the identification of more than 170 compounds, including carbohydrates, organic acids, simple phenol glycosides, triterpene glycosides, flavonoids, prenylated phenols, benzoic acid derivatives, hydroxycinnamates, dihydrochalcones, catechins, and procyanidins, most of which were identified for the first time in the plant. Extended surveys of the seasonal content of all detected compounds prove that specific metabolite variations reflect the bioactivity of R. adamsii extracts. Regarding in vitro methods, the expressed antioxidant potential of R. adamsii extracts was investigated via radical-scavenging, nitric oxide scavenging, and ferrous (II) ion chelating assays. The animal-based swimming to exhaustion test demonstrates the stimulating influence of R. adamsii extract on physical performance and endurance, concluding that the drug could act as an adaptogen. Thus, Sagan Dalya tea (R. adamsii) has confirmed its “old” application as a tonic remedy and requires further precise study as a novel adaptogenic plant.
Citations by journals
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Khimiya Rastitel'nogo Syr'ya
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Khimiya Rastitel'nogo Syr'ya
4 publications, 26.67%
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Plants
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2 publications, 13.33%
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Russian Journal of Bioorganic Chemistry
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Molecules
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Molecules
1 publication, 6.67%
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Russian Chemical Bulletin
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1 publication, 6.67%
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Chemistry of Natural Compounds
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1 publication, 6.67%
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South African Journal of Botany
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South African Journal of Botany
1 publication, 6.67%
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Agronomy
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Agronomy
1 publication, 6.67%
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International Journal of Circumpolar Health
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International Journal of Circumpolar Health
1 publication, 6.67%
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Citations by publishers
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Multidisciplinary Digital Publishing Institute (MDPI)
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Multidisciplinary Digital Publishing Institute (MDPI)
5 publications, 33.33%
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Altai State University
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Altai State University
4 publications, 26.67%
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Springer Nature
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Springer Nature
2 publications, 13.33%
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Pleiades Publishing
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Pleiades Publishing
2 publications, 13.33%
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Elsevier
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Elsevier
1 publication, 6.67%
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Taylor & Francis
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Taylor & Francis
1 publication, 6.67%
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- We do not take into account publications that without a DOI.
- Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
- Statistics recalculated weekly.
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Olennikov D. N., Nikolaev V. M., Chirikova N. K. Sagan Dalya Tea, a New “Old” Probable Adaptogenic Drug: Metabolic Characterization and Bioactivity Potentials of Rhododendron adamsii Leaves // Antioxidants. 2021. Vol. 10. No. 6. p. 863.
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Olennikov D. N., Nikolaev V. M., Chirikova N. K. Sagan Dalya Tea, a New “Old” Probable Adaptogenic Drug: Metabolic Characterization and Bioactivity Potentials of Rhododendron adamsii Leaves // Antioxidants. 2021. Vol. 10. No. 6. p. 863.
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TY - JOUR
DO - 10.3390/antiox10060863
UR - https://doi.org/10.3390%2Fantiox10060863
TI - Sagan Dalya Tea, a New “Old” Probable Adaptogenic Drug: Metabolic Characterization and Bioactivity Potentials of Rhododendron adamsii Leaves
T2 - Antioxidants
AU - Nikolaev, Vyacheslav M
AU - Chirikova, Nadezhda K
AU - Olennikov, Daniil Nikolaevich
PY - 2021
DA - 2021/05/27 00:00:00
PB - Multidisciplinary Digital Publishing Institute (MDPI)
SP - 863
IS - 6
VL - 10
SN - 2076-3921
ER -
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@article{2021_Olennikov,
author = {Vyacheslav M Nikolaev and Nadezhda K Chirikova and Daniil Nikolaevich Olennikov},
title = {Sagan Dalya Tea, a New “Old” Probable Adaptogenic Drug: Metabolic Characterization and Bioactivity Potentials of Rhododendron adamsii Leaves},
journal = {Antioxidants},
year = {2021},
volume = {10},
publisher = {Multidisciplinary Digital Publishing Institute (MDPI)},
month = {may},
url = {https://doi.org/10.3390%2Fantiox10060863},
number = {6},
pages = {863},
doi = {10.3390/antiox10060863}
}
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Olennikov, Daniil Nikolaevich, et al. “Sagan Dalya Tea, a New “Old” Probable Adaptogenic Drug: Metabolic Characterization and Bioactivity Potentials of Rhododendron adamsii Leaves.” Antioxidants, vol. 10, no. 6, May. 2021, p. 863. https://doi.org/10.3390%2Fantiox10060863.
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