Quaternary Ammonium Compounds (QACs) and Ionic Liquids (ILs) as Biocides: From Simple Antiseptics to Tunable Antimicrobials
Quaternary ammonium compounds (QACs) belong to a well-known class of cationic biocides with a broad spectrum of antimicrobial activity. They are used as essential components in surfactants, personal hygiene products, cosmetics, softeners, dyes, biological dyes, antiseptics, and disinfectants. Simple but varied in their structure, QACs are divided into several subclasses: Mono-, bis-, multi-, and poly-derivatives. Since the beginning of the 20th century, a significant amount of work has been dedicated to the advancement of this class of biocides. Thus, more than 700 articles on QACs were published only in 2020, according to the modern literature. The structural variability and diverse biological activity of ionic liquids (ILs) make them highly prospective for developing new types of biocides. QACs and ILs bear a common key element in the molecular structure–quaternary positively charged nitrogen atoms within a cyclic or acyclic structural framework. The state-of-the-art research level and paramount demand in modern society recall the rapid development of a new generation of tunable antimicrobials. This review focuses on the main QACs exhibiting antimicrobial and antifungal properties, commercial products based on QACs, and the latest discoveries in QACs and ILs connected with biocide development.
Citations by journals
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International Journal of Molecular Sciences
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Molecules
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5 publications, 4.63%
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Journal of Molecular Liquids
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Journal of Molecular Liquids
5 publications, 4.63%
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ACS Infectious Diseases
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ACS Infectious Diseases
4 publications, 3.7%
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Separations
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2 publications, 1.85%
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Antibiotics
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Antibiotics
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Medicinal Chemistry Research
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Medicinal Chemistry Research
2 publications, 1.85%
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Russian Journal of General Chemistry
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Russian Journal of General Chemistry
2 publications, 1.85%
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Russian Journal of Organic Chemistry
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Russian Journal of Organic Chemistry
2 publications, 1.85%
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Russian Chemical Bulletin
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Russian Chemical Bulletin
2 publications, 1.85%
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Microorganisms
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Microorganisms
2 publications, 1.85%
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Chemistry of Heterocyclic Compounds
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Chemistry of Heterocyclic Compounds
2 publications, 1.85%
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Chemistry and Biodiversity
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Chemistry and Biodiversity
1 publication, 0.93%
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Angewandte Chemie - International Edition
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Angewandte Chemie - International Edition
1 publication, 0.93%
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Journal of Functional Biomaterials
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Journal of Functional Biomaterials
1 publication, 0.93%
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Journal of Medicinal Chemistry
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Journal of Medicinal Chemistry
1 publication, 0.93%
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Sensors
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Sensors
1 publication, 0.93%
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ACS applied materials & interfaces
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ACS applied materials & interfaces
1 publication, 0.93%
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ACS Applied Bio Materials
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ACS Applied Bio Materials
1 publication, 0.93%
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Biomedicines
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Biomedicines
1 publication, 0.93%
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Pharmaceuticals
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Pharmaceuticals
1 publication, 0.93%
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Biology
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Biology
1 publication, 0.93%
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Frontiers in Microbiology
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Frontiers in Microbiology
1 publication, 0.93%
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Frontiers in Toxicology
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Frontiers in Toxicology
1 publication, 0.93%
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Acta Parasitologica
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Acta Parasitologica
1 publication, 0.93%
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Cellulose
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Cellulose
1 publication, 0.93%
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Pharmaceutical Research
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Pharmaceutical Research
1 publication, 0.93%
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Polymer Bulletin
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Polymer Bulletin
1 publication, 0.93%
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Advances in Colloid and Interface Science
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Advances in Colloid and Interface Science
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Citations by publishers
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Multidisciplinary Digital Publishing Institute (MDPI)
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Multidisciplinary Digital Publishing Institute (MDPI)
30 publications, 27.78%
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Elsevier
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Elsevier
25 publications, 23.15%
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Springer Nature
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Springer Nature
14 publications, 12.96%
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American Chemical Society (ACS)
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American Chemical Society (ACS)
10 publications, 9.26%
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Pleiades Publishing
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Pleiades Publishing
8 publications, 7.41%
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Wiley
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Wiley
7 publications, 6.48%
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Frontiers Media S.A.
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Frontiers Media S.A.
3 publications, 2.78%
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Taylor & Francis
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Taylor & Francis
2 publications, 1.85%
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Royal Society of Chemistry (RSC)
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Royal Society of Chemistry (RSC)
2 publications, 1.85%
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IOP Publishing
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IOP Publishing
1 publication, 0.93%
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The Chemical Society of Japan
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The Chemical Society of Japan
1 publication, 0.93%
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