Open Access
Open access
International Journal of Molecular Sciences, volume 22, issue 13, pages 6793

Quaternary Ammonium Compounds (QACs) and Ionic Liquids (ILs) as Biocides: From Simple Antiseptics to Tunable Antimicrobials

Publication typeJournal Article
Publication date2021-06-24
Quartile SCImago
Q1
Quartile WOS
Q1
Impact factor5.6
ISSN16616596, 14220067
PubMed ID:  34202677
Catalysis
Organic Chemistry
Inorganic Chemistry
Physical and Theoretical Chemistry
Computer Science Applications
Spectroscopy
Molecular Biology
General Medicine
Abstract

Quaternary ammonium compounds (QACs) belong to a well-known class of cationic biocides with a broad spectrum of antimicrobial activity. They are used as essential components in surfactants, personal hygiene products, cosmetics, softeners, dyes, biological dyes, antiseptics, and disinfectants. Simple but varied in their structure, QACs are divided into several subclasses: Mono-, bis-, multi-, and poly-derivatives. Since the beginning of the 20th century, a significant amount of work has been dedicated to the advancement of this class of biocides. Thus, more than 700 articles on QACs were published only in 2020, according to the modern literature. The structural variability and diverse biological activity of ionic liquids (ILs) make them highly prospective for developing new types of biocides. QACs and ILs bear a common key element in the molecular structure–quaternary positively charged nitrogen atoms within a cyclic or acyclic structural framework. The state-of-the-art research level and paramount demand in modern society recall the rapid development of a new generation of tunable antimicrobials. This review focuses on the main QACs exhibiting antimicrobial and antifungal properties, commercial products based on QACs, and the latest discoveries in QACs and ILs connected with biocide development.

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Vereshchagin A. N. et al. Quaternary Ammonium Compounds (QACs) and Ionic Liquids (ILs) as Biocides: From Simple Antiseptics to Tunable Antimicrobials // International Journal of Molecular Sciences. 2021. Vol. 22. No. 13. p. 6793.
GOST all authors (up to 50) Copy
Vereshchagin A. N., Frolov N. A., Egorova K. S., Seitkalieva M. M., Ananikov V. P. Quaternary Ammonium Compounds (QACs) and Ionic Liquids (ILs) as Biocides: From Simple Antiseptics to Tunable Antimicrobials // International Journal of Molecular Sciences. 2021. Vol. 22. No. 13. p. 6793.
RIS |
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RIS Copy
TY - JOUR
DO - 10.3390/ijms22136793
UR - https://doi.org/10.3390%2Fijms22136793
TI - Quaternary Ammonium Compounds (QACs) and Ionic Liquids (ILs) as Biocides: From Simple Antiseptics to Tunable Antimicrobials
T2 - International Journal of Molecular Sciences
AU - Egorova, Ksenia S
AU - Seitkalieva, Marina M
AU - Vereshchagin, Anatoly N.
AU - Frolov, Nikita A
AU - Ananikov, Valentine P.
PY - 2021
DA - 2021/06/24 00:00:00
PB - Multidisciplinary Digital Publishing Institute (MDPI)
SP - 6793
IS - 13
VL - 22
PMID - 34202677
SN - 1661-6596
SN - 1422-0067
ER -
BibTex |
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BibTex Copy
@article{2021_Vereshchagin,
author = {Ksenia S Egorova and Marina M Seitkalieva and Anatoly N. Vereshchagin and Nikita A Frolov and Valentine P. Ananikov},
title = {Quaternary Ammonium Compounds (QACs) and Ionic Liquids (ILs) as Biocides: From Simple Antiseptics to Tunable Antimicrobials},
journal = {International Journal of Molecular Sciences},
year = {2021},
volume = {22},
publisher = {Multidisciplinary Digital Publishing Institute (MDPI)},
month = {jun},
url = {https://doi.org/10.3390%2Fijms22136793},
number = {13},
pages = {6793},
doi = {10.3390/ijms22136793}
}
MLA
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MLA Copy
Vereshchagin, Anatoly N., et al. “Quaternary Ammonium Compounds (QACs) and Ionic Liquids (ILs) as Biocides: From Simple Antiseptics to Tunable Antimicrobials.” International Journal of Molecular Sciences, vol. 22, no. 13, Jun. 2021, p. 6793. https://doi.org/10.3390%2Fijms22136793.
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