Open Access
Selected Fungal Natural Products with Antimicrobial Properties
2
Department of Agriculture, Horticulture and Engineering Science, Scotland’s Rural College (SRUC), Edinburgh EH9 3JG, UK
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Publication type: Journal Article
Publication date: 2020-02-18
PubMed ID:
32085562
Organic Chemistry
Drug Discovery
Physical and Theoretical Chemistry
Pharmaceutical Science
Molecular Medicine
Analytical Chemistry
Chemistry (miscellaneous)
Abstract
Fungal natural products and their effects have been known to humankind for hundreds of years. For example, toxic ergot alkaloids produced by filamentous fungi growing on rye poisoned thousands of people and livestock throughout the Middle Ages. However, their later medicinal applications, followed by the discovery of the first class of antibiotics, penicillins and other drugs of fungal origin, such as peptidic natural products, terpenoids or polyketides, have altered the historically negative reputation of fungal “toxins”. The development of new antimicrobial drugs is currently a major global challenge, mainly due to antimicrobial resistance phenomena. Therefore, the structures, biosynthesis and antimicrobial activity of selected fungal natural products are described here.
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97
Total citations:
97
Citations from 2024:
44
(45.36%)
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MLA
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GOST
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Jakubczyk D., Dussart F. Selected Fungal Natural Products with Antimicrobial Properties // Molecules. 2020. Vol. 25. No. 4. p. 911.
GOST all authors (up to 50)
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Jakubczyk D., Dussart F. Selected Fungal Natural Products with Antimicrobial Properties // Molecules. 2020. Vol. 25. No. 4. p. 911.
Cite this
RIS
Copy
TY - JOUR
DO - 10.3390/molecules25040911
UR - https://doi.org/10.3390/molecules25040911
TI - Selected Fungal Natural Products with Antimicrobial Properties
T2 - Molecules
AU - Jakubczyk, Dorota
AU - Dussart, Francois
PY - 2020
DA - 2020/02/18
PB - MDPI
SP - 911
IS - 4
VL - 25
PMID - 32085562
SN - 1420-3049
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2020_Jakubczyk,
author = {Dorota Jakubczyk and Francois Dussart},
title = {Selected Fungal Natural Products with Antimicrobial Properties},
journal = {Molecules},
year = {2020},
volume = {25},
publisher = {MDPI},
month = {feb},
url = {https://doi.org/10.3390/molecules25040911},
number = {4},
pages = {911},
doi = {10.3390/molecules25040911}
}
Cite this
MLA
Copy
Jakubczyk, Dorota, and Francois Dussart. “Selected Fungal Natural Products with Antimicrobial Properties.” Molecules, vol. 25, no. 4, Feb. 2020, p. 911. https://doi.org/10.3390/molecules25040911.