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volume 12 issue 1 pages 98

Anti-Planktonic and Anti-Biofilm Properties of Pentacyclic Triterpenes—Asiatic Acid and Ursolic Acid as Promising Antibacterial Future Pharmaceuticals

Publication typeJournal Article
Publication date2022-01-07
scimago Q1
wos Q1
SJR1.333
CiteScore9.2
Impact factor4.8
ISSN2218273X
PubMed ID:  35053246
Biochemistry
Molecular Biology
Abstract

Due to the ever-increasing number of multidrug-resistant bacteria, research concerning plant-derived compounds with antimicrobial mechanisms of action has been conducted. Pentacyclic triterpenes, which have a broad spectrum of medicinal properties, are one of such groups. Asiatic acid (AA) and ursolic acid (UA), which belong to this group, exhibit diverse biological activities that include antioxidant, anti-inflammatory, diuretic, and immunostimulatory. Some of these articles usually contain only a short section describing the antibacterial effects of AA or UA. Therefore, our review article aims to provide the reader with a broader understanding of the activity of these acids against pathogenic bacteria. The bacteria in the human body can live in the planktonic form and create a biofilm structure. Therefore, we found it valuable to present the action of AA and UA on both planktonic and biofilm cultures. The article also presents mechanisms of the biological activity of these substances against microorganisms.

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GOST Copy
Sycz Z., Tichaczek Goska D., Wojnicz D. Anti-Planktonic and Anti-Biofilm Properties of Pentacyclic Triterpenes—Asiatic Acid and Ursolic Acid as Promising Antibacterial Future Pharmaceuticals // Biomolecules. 2022. Vol. 12. No. 1. p. 98.
GOST all authors (up to 50) Copy
Sycz Z., Tichaczek Goska D., Wojnicz D. Anti-Planktonic and Anti-Biofilm Properties of Pentacyclic Triterpenes—Asiatic Acid and Ursolic Acid as Promising Antibacterial Future Pharmaceuticals // Biomolecules. 2022. Vol. 12. No. 1. p. 98.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.3390/biom12010098
UR - https://doi.org/10.3390/biom12010098
TI - Anti-Planktonic and Anti-Biofilm Properties of Pentacyclic Triterpenes—Asiatic Acid and Ursolic Acid as Promising Antibacterial Future Pharmaceuticals
T2 - Biomolecules
AU - Sycz, Zuzanna
AU - Tichaczek Goska, Dorota
AU - Wojnicz, Dorota
PY - 2022
DA - 2022/01/07
PB - MDPI
SP - 98
IS - 1
VL - 12
PMID - 35053246
SN - 2218-273X
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2022_Sycz,
author = {Zuzanna Sycz and Dorota Tichaczek Goska and Dorota Wojnicz},
title = {Anti-Planktonic and Anti-Biofilm Properties of Pentacyclic Triterpenes—Asiatic Acid and Ursolic Acid as Promising Antibacterial Future Pharmaceuticals},
journal = {Biomolecules},
year = {2022},
volume = {12},
publisher = {MDPI},
month = {jan},
url = {https://doi.org/10.3390/biom12010098},
number = {1},
pages = {98},
doi = {10.3390/biom12010098}
}
MLA
Cite this
MLA Copy
Sycz, Zuzanna, et al. “Anti-Planktonic and Anti-Biofilm Properties of Pentacyclic Triterpenes—Asiatic Acid and Ursolic Acid as Promising Antibacterial Future Pharmaceuticals.” Biomolecules, vol. 12, no. 1, Jan. 2022, p. 98. https://doi.org/10.3390/biom12010098.