Open Access
Antimicrobial and Amyloidogenic Activity of Peptides. Can Antimicrobial Peptides Be Used against SARS-CoV-2?
Publication type: Journal Article
Publication date: 2020-12-15
scimago Q1
wos Q1
SJR: 1.273
CiteScore: 9.0
Impact factor: 4.9
ISSN: 16616596, 14220067
PubMed ID:
33333996
Catalysis
Organic Chemistry
Inorganic Chemistry
Physical and Theoretical Chemistry
Computer Science Applications
Spectroscopy
Molecular Biology
General Medicine
Abstract
At present, much attention is paid to the use of antimicrobial peptides (AMPs) of natural and artificial origin to combat pathogens. AMPs have several points that determine their biological activity. We analyzed the structural properties of AMPs, as well as described their mechanism of action and impact on pathogenic bacteria and viruses. Recently published data on the development of new AMP drugs based on a combination of molecular design and genetic engineering approaches are presented. In this article, we have focused on information on the amyloidogenic properties of AMP. This review examines AMP development strategies from the perspective of the current high prevalence of antibiotic-resistant bacteria, and the potential prospects and challenges of using AMPs against infection caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
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Metrics
57
Total citations:
57
Citations from 2024:
15
(26.79%)
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BibTex |
MLA
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GOST
Copy
Kurpe S. R. et al. Antimicrobial and Amyloidogenic Activity of Peptides. Can Antimicrobial Peptides Be Used against SARS-CoV-2? // International Journal of Molecular Sciences. 2020. Vol. 21. No. 24. p. 9552.
GOST all authors (up to 50)
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Kurpe S. R., Grishin S. Y., Surin A. K., PANFILOV A. V., Slizen M. V., Chowdhury D. D., Галзитская О. В. Antimicrobial and Amyloidogenic Activity of Peptides. Can Antimicrobial Peptides Be Used against SARS-CoV-2? // International Journal of Molecular Sciences. 2020. Vol. 21. No. 24. p. 9552.
Cite this
RIS
Copy
TY - JOUR
DO - 10.3390/ijms21249552
UR - https://doi.org/10.3390/ijms21249552
TI - Antimicrobial and Amyloidogenic Activity of Peptides. Can Antimicrobial Peptides Be Used against SARS-CoV-2?
T2 - International Journal of Molecular Sciences
AU - Kurpe, Stanislav R
AU - Grishin, Sergei Y.
AU - Surin, Alexey K.
AU - PANFILOV, ALEXANDER V.
AU - Slizen, Mikhail V
AU - Chowdhury, Dipanwita Dutta
AU - Галзитская, О. В.
PY - 2020
DA - 2020/12/15
PB - MDPI
SP - 9552
IS - 24
VL - 21
PMID - 33333996
SN - 1661-6596
SN - 1422-0067
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2020_Kurpe,
author = {Stanislav R Kurpe and Sergei Y. Grishin and Alexey K. Surin and ALEXANDER V. PANFILOV and Mikhail V Slizen and Dipanwita Dutta Chowdhury and О. В. Галзитская},
title = {Antimicrobial and Amyloidogenic Activity of Peptides. Can Antimicrobial Peptides Be Used against SARS-CoV-2?},
journal = {International Journal of Molecular Sciences},
year = {2020},
volume = {21},
publisher = {MDPI},
month = {dec},
url = {https://doi.org/10.3390/ijms21249552},
number = {24},
pages = {9552},
doi = {10.3390/ijms21249552}
}
Cite this
MLA
Copy
Kurpe, Stanislav R., et al. “Antimicrobial and Amyloidogenic Activity of Peptides. Can Antimicrobial Peptides Be Used against SARS-CoV-2?.” International Journal of Molecular Sciences, vol. 21, no. 24, Dec. 2020, p. 9552. https://doi.org/10.3390/ijms21249552.