Open Access
International Journal of Molecular Sciences, volume 23, issue 12, pages 6645
Cationic Surfactants as Disinfectants against SARS-CoV-2
Karamov Eduard
1, 2
,
Larichev Viktor F
1
,
Kornilaeva Galina V.
1
,
Fedyakina Irina T
1
,
Turgiev Ali S
1, 2
,
Shibaev Andrey V
3
,
Philippova O.E.
3
,
Publication type: Journal Article
Publication date: 2022-06-14
Quartile SCImago
Q1
Quartile WOS
Q1
Impact factor: 5.6
ISSN: 16616596, 14220067
PubMed ID:
35743090
Catalysis
Organic Chemistry
Inorganic Chemistry
Physical and Theoretical Chemistry
Computer Science Applications
Spectroscopy
Molecular Biology
General Medicine
Abstract
The virucidal activity of a series of cationic surfactants differing in the length and number of hydrophobic tails (at the same hydrophilic head) and the structure of the hydrophilic head (at the same length of the hydrophobic n-alkyl tail) was compared. It was shown that an increase in the length and number of hydrophobic tails, as well as the presence of a benzene ring in the surfactant molecule, enhance the virucidal activity of the surfactant against SARS-CoV-2. This may be due to the more pronounced ability of such surfactants to penetrate and destroy the phospholipid membrane of the virus. Among the cationic surfactants studied, didodecyldimethylammonium bromide was shown to be the most efficient as a disinfectant, its 50% effective concentration (EC50) being equal to 0.016 mM. Two surfactants (didodecyldimethylammonium bromide and benzalkonium chloride) can deactivate SARS-CoV-2 in as little as 5 s.
Citations by journals
|
1
|
|
|
Sensors
|
Sensors
1 publication, 7.69%
|
|
Antiviral Research
|
Antiviral Research
1 publication, 7.69%
|
|
Journal of Drug Delivery Science and Technology
|
Journal of Drug Delivery Science and Technology
1 publication, 7.69%
|
|
ACS Applied Bio Materials
|
ACS Applied Bio Materials
1 publication, 7.69%
|
|
Journal of Hazardous Materials
|
Journal of Hazardous Materials
1 publication, 7.69%
|
|
Journal of Molecular Liquids
|
Journal of Molecular Liquids
1 publication, 7.69%
|
|
Brazilian Journal of Medical and Biological Research
|
Brazilian Journal of Medical and Biological Research
1 publication, 7.69%
|
|
International Journal of Molecular Sciences
|
International Journal of Molecular Sciences
1 publication, 7.69%
|
|
Polymer Science - Series A
|
Polymer Science - Series A
1 publication, 7.69%
|
|
Biochimica et Biophysica Acta - General Subjects
|
Biochimica et Biophysica Acta - General Subjects
1 publication, 7.69%
|
|
Journal of Colloid and Interface Science
|
Journal of Colloid and Interface Science
1 publication, 7.69%
|
|
Microorganisms
|
Microorganisms
1 publication, 7.69%
|
|
1
|
Citations by publishers
|
1
2
3
4
5
6
|
|
|
Elsevier
|
Elsevier
6 publications, 46.15%
|
|
Multidisciplinary Digital Publishing Institute (MDPI)
|
Multidisciplinary Digital Publishing Institute (MDPI)
3 publications, 23.08%
|
|
American Chemical Society (ACS)
|
American Chemical Society (ACS)
1 publication, 7.69%
|
|
|
, 1, 7.69%
1 publication, 7.69%
|
|
Pleiades Publishing
|
Pleiades Publishing
1 publication, 7.69%
|
|
1
2
3
4
5
6
|
- We do not take into account publications that without a DOI.
- Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
- Statistics recalculated weekly.
{"yearsCitations":{"type":"bar","data":{"show":true,"labels":[2022,2023,2024],"ids":[0,0,0],"codes":[0,0,0],"imageUrls":["","",""],"datasets":[{"label":"Citations number","data":[1,9,3],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6"],"percentage":["7.69","69.23","23.08"],"barThickness":null}]},"options":{"indexAxis":"x","maintainAspectRatio":true,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"}},"x":{"ticks":{"stepSize":1,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"}}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Citations per year","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}},"journals":{"type":"bar","data":{"show":true,"labels":["Sensors","Antiviral Research","Journal of Drug Delivery Science and Technology","ACS Applied Bio Materials","Journal of Hazardous Materials","Journal of Molecular Liquids","Brazilian Journal of Medical and Biological Research","International Journal of Molecular Sciences","Polymer Science - Series A","Biochimica et Biophysica Acta - General Subjects","Journal of Colloid and Interface Science","Microorganisms"],"ids":[18435,22274,17907,21728,23695,13597,3557,14627,181,5266,24202,6197],"codes":[0,0,0,0,0,0,0,0,0,0,0,0],"imageUrls":["\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/iLiQsFqFaSEx6chlGQ5fbAwF6VYU3WWa08hkss0g_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/cbyhSrovF1eOU291As4BiIdeqBkjMT198ldCev8O_medium.webp","\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp","\/storage\/images\/resized\/oZgeErrVFhuDksyqFURLvYS1wtVSBWczh001igGo_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp"],"datasets":[{"label":"","data":[1,1,1,1,1,1,1,1,1,1,1,1],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6"],"percentage":[7.69,7.69,7.69,7.69,7.69,7.69,7.69,7.69,7.69,7.69,7.69,7.69],"barThickness":13}]},"options":{"indexAxis":"y","maintainAspectRatio":false,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"}},"x":{"ticks":{"stepSize":null,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"}}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Journals","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}},"publishers":{"type":"bar","data":{"show":true,"labels":["Elsevier","Multidisciplinary Digital Publishing Institute (MDPI)","American Chemical Society (ACS)","","Pleiades Publishing"],"ids":[17,202,40,1305,101],"codes":[0,0,0,0,0],"imageUrls":["\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp","\/storage\/images\/resized\/iLiQsFqFaSEx6chlGQ5fbAwF6VYU3WWa08hkss0g_medium.webp","","\/storage\/images\/resized\/oZgeErrVFhuDksyqFURLvYS1wtVSBWczh001igGo_medium.webp"],"datasets":[{"label":"","data":[6,3,1,1,1],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6"],"percentage":[46.15,23.08,7.69,7.69,7.69],"barThickness":13}]},"options":{"indexAxis":"y","maintainAspectRatio":false,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"}},"x":{"ticks":{"stepSize":null,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"}}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Publishers","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}}}
Metrics
Cite this
GOST |
RIS |
BibTex |
MLA
Cite this
GOST
Copy
Karamov E. et al. Cationic Surfactants as Disinfectants against SARS-CoV-2 // International Journal of Molecular Sciences. 2022. Vol. 23. No. 12. p. 6645.
GOST all authors (up to 50)
Copy
Karamov E., Larichev V. F., Kornilaeva G. V., Fedyakina I. T., Turgiev A. S., Shibaev A. V., Molchanov V. S., Philippova O., Khokhlov A. R. Cationic Surfactants as Disinfectants against SARS-CoV-2 // International Journal of Molecular Sciences. 2022. Vol. 23. No. 12. p. 6645.
Cite this
RIS
Copy
TY - JOUR
DO - 10.3390/ijms23126645
UR - https://doi.org/10.3390%2Fijms23126645
TI - Cationic Surfactants as Disinfectants against SARS-CoV-2
T2 - International Journal of Molecular Sciences
AU - Larichev, Viktor F
AU - Kornilaeva, Galina V.
AU - Fedyakina, Irina T
AU - Turgiev, Ali S
AU - Khokhlov, Alexei R.
AU - Karamov, Eduard
AU - Shibaev, Andrey V
AU - Molchanov, Vyacheslav S
AU - Philippova, O.E.
PY - 2022
DA - 2022/06/14 00:00:00
PB - Multidisciplinary Digital Publishing Institute (MDPI)
SP - 6645
IS - 12
VL - 23
PMID - 35743090
SN - 1661-6596
SN - 1422-0067
ER -
Cite this
BibTex
Copy
@article{2022_Karamov,
author = {Viktor F Larichev and Galina V. Kornilaeva and Irina T Fedyakina and Ali S Turgiev and Alexei R. Khokhlov and Eduard Karamov and Andrey V Shibaev and Vyacheslav S Molchanov and O.E. Philippova},
title = {Cationic Surfactants as Disinfectants against SARS-CoV-2},
journal = {International Journal of Molecular Sciences},
year = {2022},
volume = {23},
publisher = {Multidisciplinary Digital Publishing Institute (MDPI)},
month = {jun},
url = {https://doi.org/10.3390%2Fijms23126645},
number = {12},
pages = {6645},
doi = {10.3390/ijms23126645}
}
Cite this
MLA
Copy
Karamov, Eduard, et al. “Cationic Surfactants as Disinfectants against SARS-CoV-2.” International Journal of Molecular Sciences, vol. 23, no. 12, Jun. 2022, p. 6645. https://doi.org/10.3390%2Fijms23126645.