Open Access
Open access
MDPI
Marine Drugs
,  volume 16 ,  issue 12 ,  pages 509

Antiviral and Antioxidant Properties of Echinochrome A

Sergey Fedoreyev 1
, 
Sergey A Fedoreyev 1
, 
Natalia Krylova 2
, 
Natalia Mishchenko 1
, 
N.P Mischenko 1
, 
Elena Vasileva 1
, 
Elena A Vasileva 1
, 
Evgeny Pislyagin 1
, 
E.A. Pislyagin 1
, 
Olga Iunikhina 2
, 
Olga V Iunikhina 2
, 
Vyacheslav Lavrov 3
, 
Vyacheslav F Lavrov 3
, 
Oksana Svitich 3
, 
Oksana A. Svitich 3
, 
Linna Ebralidze 3
, 
Linna K Ebralidze 3
, 
Galina Leonova 2
, 
Galina N. Leonova 2
1
 
2
 
G.P. Somov Institute of Epidemiology and Microbiology, FEB RAS, Vladivostok 690087, Russia | 
3
 
Publication type: Journal Article
Publication date: 2018-12-15
MDPI
scimago Q1
wos Q1
SJR: 1.030
CiteScore: 10.1
Impact factor: 5.4
ISSN: 16603397
DOI:  10.3390/md16120509
PubMed ID:  30558297
Drug Discovery
Pharmaceutical Science
Pharmacology, Toxicology and Pharmaceutics (miscellaneous)
Abstract

The aim of this study was to examine the in vitro antioxidant and antiviral activities of echinochrome A and echinochrome-based antioxidant composition against tick-borne encephalitis virus (TBEV) and herpes simplex virus type 1 (HSV-1). The antioxidant composition, which is a mixture of echinochrome A, ascorbic acid, and α-tocopherol (5:5:1), showed higher antioxidant and antiviral effects than echinochrome A. We suppose that echinochrome A and its composition can both directly affect virus particles and indirectly enhance antioxidant defense mechanisms in the hosting cell. The obtained results allow considering the echinochrome A and the composition of antioxidants on its basis as the promising agents with the both antioxidant and antiviral activities.

Found 
Found 
3 citations
Pislyagin Evgeny
79 publications,  1 117 citations,  1 review
h-index: 20
G. B. Elyakov Pacific Institute of Bioorganic Chemistry of the Far Eastern Branch of the Russian Academy of Sciences
G. B. Elyakov Pacific Institute of Bioorganic Chemistry of the Far Eastern Branch of the Russian Academy of Sciences
2 citations
Kravchenko Anna
PhD in Chemistry
26 publications,  432 citations,  1 review
h-index: 13
G. B. Elyakov Pacific Institute of Bioorganic Chemistry of the Far Eastern Branch of the Russian Academy of Sciences
G. B. Elyakov Pacific Institute of Bioorganic Chemistry of the Far Eastern Branch of the Russian Academy of Sciences
Research interests
Bioorganic chemistry
Polymer Chemistry
Polysaccharides of red algae
2 citations
Ermak I
🥼 🤝
DSc in Chemistry
88 publications,  1 766 citations
h-index: 26
G. B. Elyakov Pacific Institute of Bioorganic Chemistry of the Far Eastern Branch of the Russian Academy of Sciences
G. B. Elyakov Pacific Institute of Bioorganic Chemistry of the Far Eastern Branch of the Russian Academy of Sciences
1 citation
Osolodkin Dmitry
🥼 🤝
PhD in Chemistry
80 publications,  1 731 citations
h-index: 23
Sechenov First Moscow State Medical University
Sechenov First Moscow State Medical University
M.P. Chumakov Federal Scientific Center for Research and Development of Immunobiological Drugs of the Russian Academy of Sciences
M.P. Chumakov Federal Scientific Center for Research and Development of Immunobiological Drugs of the Russian Academy of Sciences
Research interests
Antiviral drugs
Chemoinformatics
Medicinal Chemistry
1 citation
Pelageev Dmitry
PhD in Chemistry
27 publications,  292 citations,  98 reviews
h-index: 11
G. B. Elyakov Pacific Institute of Bioorganic Chemistry of the Far Eastern Branch of the Russian Academy of Sciences
G. B. Elyakov Pacific Institute of Bioorganic Chemistry of the Far Eastern Branch of the Russian Academy of Sciences
1 citation
Demidova Natalia
19 publications,  77 citations
h-index: 4
N. F. Gamaleya National Research Center for Epidemiology and Microbiology of the Ministry of Health of the Russian Federation
N. F. Gamaleya National Research Center for Epidemiology and Microbiology of the Ministry of Health of the Russian Federation
Research interests
Herpesviruses
Molecular biology
Virology
1 citation
Parra-Saldivar Roberto
🥼 🤝
PhD in Biological/biomedical sciences, professor, full member of the Mexican Academy of Sciences
334 publications,  14 529 citations,  66 reviews
h-index: 64
Cranfield University
Cranfield University
Research interests
Renewable energy
1 citation
Grigorchuk Valeriya
60 publications,  786 citations
h-index: 17
Federal Scientific Center of the East Asia Terrestrial Biodiversity of the Far Eastern Branch of the Russian Academy of Sciences
Federal Scientific Center of the East Asia Terrestrial Biodiversity of the Far Eastern Branch of the Russian Academy of Sciences
Research interests
Biochemistry
Chromatography
Lipid membranes
Mass Spectrometry
Secondary metabolites
1 citation
Wagener Frank
90 publications,  3 687 citations,  16 reviews
h-index: 31
Radboud University Nijmegen Medical Centre
Radboud University Nijmegen Medical Centre
Research interests
Fibrosis
1 citation
Romano Giovanna
123 publications,  6 225 citations,  9 reviews
h-index: 42
Stazione Zoologica Anton Dohrn
Stazione Zoologica Anton Dohrn

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GOST |
Cite this
GOST Copy
Fedoreyev S. et al. Antiviral and Antioxidant Properties of Echinochrome A // Marine Drugs. 2018. Vol. 16. No. 12. p. 509.
GOST all authors (up to 50) Copy
Fedoreyev S., Fedoreyev S. A., Krylova N., Mishchenko N., Mischenko N., Vasileva E., Vasileva E. A., Pislyagin E., Pislyagin E., Iunikhina O., Iunikhina O. V., Lavrov V., Lavrov V. F., Svitich O., Svitich O. A., Ebralidze L., Ebralidze L. K., Leonova G., Leonova G. N. Antiviral and Antioxidant Properties of Echinochrome A // Marine Drugs. 2018. Vol. 16. No. 12. p. 509.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.3390/md16120509
UR - https://www.mdpi.com/1660-3397/16/12/509
TI - Antiviral and Antioxidant Properties of Echinochrome A
T2 - Marine Drugs
AU - Fedoreyev, Sergey
AU - Fedoreyev, Sergey A
AU - Krylova, Natalia
AU - Mishchenko, Natalia
AU - Mischenko, N.P
AU - Vasileva, Elena
AU - Vasileva, Elena A
AU - Pislyagin, Evgeny
AU - Pislyagin, E.A.
AU - Iunikhina, Olga
AU - Iunikhina, Olga V
AU - Lavrov, Vyacheslav
AU - Lavrov, Vyacheslav F
AU - Svitich, Oksana
AU - Svitich, Oksana A.
AU - Ebralidze, Linna
AU - Ebralidze, Linna K
AU - Leonova, Galina
AU - Leonova, Galina N.
PY - 2018
DA - 2018/12/15
PB - MDPI
SP - 509
IS - 12
VL - 16
PMID - 30558297
SN - 1660-3397
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2018_Fedoreyev,
author = {Sergey Fedoreyev and Sergey A Fedoreyev and Natalia Krylova and Natalia Mishchenko and N.P Mischenko and Elena Vasileva and Elena A Vasileva and Evgeny Pislyagin and E.A. Pislyagin and Olga Iunikhina and Olga V Iunikhina and Vyacheslav Lavrov and Vyacheslav F Lavrov and Oksana Svitich and Oksana A. Svitich and Linna Ebralidze and Linna K Ebralidze and Galina Leonova and Galina N. Leonova},
title = {Antiviral and Antioxidant Properties of Echinochrome A},
journal = {Marine Drugs},
year = {2018},
volume = {16},
publisher = {MDPI},
month = {dec},
url = {https://www.mdpi.com/1660-3397/16/12/509},
number = {12},
pages = {509},
doi = {10.3390/md16120509}
}
MLA
Cite this
MLA Copy
Fedoreyev, Sergey, et al. “Antiviral and Antioxidant Properties of Echinochrome A.” Marine Drugs, vol. 16, no. 12, Dec. 2018, p. 509. https://www.mdpi.com/1660-3397/16/12/509.