Open Access

Molecules

, том 28 , издание 4 , страницы 1603

Hybrid Nanosystems of Antibiotics with Metal Nanoparticles—Novel Antibacterial Agents

Tatyana I. Shabatina ^{1, 2}

Olga I. Vernaya ^{1, 2}

Mikhail Y. Melnikov ¹

Скрыть аффилиации авторов Показать аффилиации авторов: 2 аффилиации

Department of Chemistry, M.V. Lomonosov Moscow State University, 119991 Moscow, Russia |

Department of Fundamental Sciences, N.E. Bauman Moscow Technical University, 105005 Moscow, Russia |

Тип публикации: Journal Article

Дата публикации: 2023-02-07

MDPI

Molecules

scimago Q1

wos Q2

БС1

SJR: 0.865

CiteScore: 8.6

Impact factor: 4.6

ISSN: 14203049

DOI: 10.3390/molecules28041603

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PubMed ID: 36838591

Organic Chemistry

Drug Discovery

Physical and Theoretical Chemistry

Pharmaceutical Science

Molecular Medicine

Analytical Chemistry

Chemistry (miscellaneous)

Краткое описание

The appearance and increasing number of microorganisms resistant to the action of antibiotics is one of the global problems of the 21st century. Already, the duration of therapeutic treatment and mortality from infectious diseases caused by pathogenic microorganisms have increased significantly over the last few decades. Nanoscale inorganic materials (metals and metal oxides) with antimicrobial potential are a promising solution to this problem. Here we discuss possible mechanisms of pathogenic microorganisms’ resistance to antibiotics, proposed mechanisms of action of inorganic nanoparticles on bacterial cells, and the possibilities and benefits of their combined use with antibacterial drugs. The prospects of using metal and metal oxide nanoparticles as carriers in targeted delivery systems for antibacterial compositions are also discussed.

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Российский национальный исследовательский медицинский университет имени Н. И. Пирогова

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Shabatina T. I. et al. Hybrid Nanosystems of Antibiotics with Metal Nanoparticles—Novel Antibacterial Agents // Molecules. 2023. Vol. 28. No. 4. p. 1603.

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Shabatina T. I., Vernaya O. I., Melnikov M. Y. Hybrid Nanosystems of Antibiotics with Metal Nanoparticles—Novel Antibacterial Agents // Molecules. 2023. Vol. 28. No. 4. p. 1603.

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TY - JOUR

DO - 10.3390/molecules28041603

UR - https://doi.org/10.3390/molecules28041603

TI - Hybrid Nanosystems of Antibiotics with Metal Nanoparticles—Novel Antibacterial Agents

T2 - Molecules

AU - Shabatina, Tatyana I.

AU - Vernaya, Olga I.

AU - Melnikov, Mikhail Y.

PY - 2023

DA - 2023/02/07

PB - MDPI

SP - 1603

IS - 4

VL - 28

PMID - 36838591

SN - 1420-3049

ER -

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@article{2023_Shabatina,

author = {Tatyana I. Shabatina and Olga I. Vernaya and Mikhail Y. Melnikov},

title = {Hybrid Nanosystems of Antibiotics with Metal Nanoparticles—Novel Antibacterial Agents},

journal = {Molecules},

year = {2023},

volume = {28},

publisher = {MDPI},

month = {feb},

url = {https://doi.org/10.3390/molecules28041603},

number = {4},

pages = {1603},

doi = {10.3390/molecules28041603}

}

MLA

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Shabatina, Tatyana I., et al. “Hybrid Nanosystems of Antibiotics with Metal Nanoparticles—Novel Antibacterial Agents.” Molecules, vol. 28, no. 4, Feb. 2023, p. 1603. https://doi.org/10.3390/molecules28041603.

Издатель

MDPI

Журнал

Molecules

scimago Q1

wos Q2

БС1

SJR

0.865

CiteScore

8.6

Impact factor

4.6

ISSN

14203049 (Print, Electronic)

Профили

Мелников Михаил Я