Open Access
Pharmaceutics, volume 14, issue 3, pages 575
Development of Submicrocapsules Based on Co-Assembled Like-Charged Silica Nanoparticles and Detonation Nanodiamonds and Polyelectrolyte Layers
Palamarchuk Konstantin V
1
,
Borodina Tatiana N
2
,
Kostenko Anastasia V
1, 3
,
Chesnokov Yu.M.
1, 2
,
Kamyshinsky Roman A.
1, 2, 3
,
Palamarchuk Natalya P
1, 3
,
Yudina Elena B
4
,
Bukreeva Tatiana V
1, 2
1
2
Publication type: Journal Article
Publication date: 2022-03-05
PubMed ID:
35335951
Pharmaceutical Science
Abstract
Capsules with shells based on nanoparticles of different nature co-assembled at the interface of liquid phases of emulsion are promising carriers of lipophilic drugs. To obtain such capsules, theoretically using the Derjaguin–Landau–Verwey–Overbeek (DLVO) theory and experimentally using dynamic light-scattering (DLS) and transmission electron microscopy (TEM) methods, the interaction of like-charged silica nanoparticles and detonation nanodiamonds in an aqueous solution was studied and their ratios selected for the formation of submicron-sized colloidosomes. The resulting colloidosomes were modified with additional layers of nanoparticles and polyelectrolytes, applying LbL technology. As a model anti-cancer drug, thymoquinone was loaded into the developed capsules, demonstrating a significant delay of the release as a result of colloidosome surface modification. Fluorescence flow cytometry and confocal laser scanning microscopy showed efficient internalization of the capsules by MCF7 cancer cells. The obtained results demonstrated a high potential for nanomedicine application in the field of the drug-delivery system development.
Citations by journals
|
1
2
|
|
|
Colloid Journal
|
Colloid Journal
2 publications, 50%
|
|
Fullerenes Nanotubes and Carbon Nanostructures
|
Fullerenes Nanotubes and Carbon Nanostructures
1 publication, 25%
|
|
International Journal of Biological Macromolecules
|
International Journal of Biological Macromolecules
1 publication, 25%
|
|
1
2
|
Citations by publishers
|
1
2
|
|
|
Pleiades Publishing
|
Pleiades Publishing
2 publications, 50%
|
|
Taylor & Francis
|
Taylor & Francis
1 publication, 25%
|
|
Elsevier
|
Elsevier
1 publication, 25%
|
|
1
2
|
- We do not take into account publications that without a DOI.
- Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
- Statistics recalculated weekly.
{"yearsCitations":{"type":"bar","data":{"show":true,"labels":[2022,2023,2024],"ids":[0,0,0],"codes":[0,0,0],"imageUrls":["","",""],"datasets":[{"label":"Citations number","data":[2,1,1],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6"],"percentage":["50","25","25"],"barThickness":null}]},"options":{"indexAxis":"x","maintainAspectRatio":true,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"}},"x":{"ticks":{"stepSize":1,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"}}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Citations per year","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}},"journals":{"type":"bar","data":{"show":true,"labels":["Colloid Journal","Fullerenes Nanotubes and Carbon Nanostructures","International Journal of Biological Macromolecules"],"ids":[3923,16963,23035],"codes":[0,0,0],"imageUrls":["\/storage\/images\/resized\/oZgeErrVFhuDksyqFURLvYS1wtVSBWczh001igGo_medium.webp","\/storage\/images\/resized\/5YZtvLvkPZuc2JHOaZsjCvGSHFCuC3drUwN3YAc5_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp"],"datasets":[{"label":"","data":[2,1,1],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6"],"percentage":[50,25,25],"barThickness":13}]},"options":{"indexAxis":"y","maintainAspectRatio":false,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"}},"x":{"ticks":{"stepSize":null,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"}}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Journals","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}},"publishers":{"type":"bar","data":{"show":true,"labels":["Pleiades Publishing","Taylor & Francis","Elsevier"],"ids":[101,18,17],"codes":[0,0,0],"imageUrls":["\/storage\/images\/resized\/oZgeErrVFhuDksyqFURLvYS1wtVSBWczh001igGo_medium.webp","\/storage\/images\/resized\/5YZtvLvkPZuc2JHOaZsjCvGSHFCuC3drUwN3YAc5_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp"],"datasets":[{"label":"","data":[2,1,1],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6"],"percentage":[50,25,25],"barThickness":13}]},"options":{"indexAxis":"y","maintainAspectRatio":false,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"}},"x":{"ticks":{"stepSize":null,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"}}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Publishers","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}}}
Metrics
Cite this
GOST |
RIS |
BibTex |
MLA
Cite this
GOST
Copy
Palamarchuk K. V. et al. Development of Submicrocapsules Based on Co-Assembled Like-Charged Silica Nanoparticles and Detonation Nanodiamonds and Polyelectrolyte Layers // Pharmaceutics. 2022. Vol. 14. No. 3. p. 575.
GOST all authors (up to 50)
Copy
Palamarchuk K. V., Borodina T. N., Kostenko A. V., Chesnokov Y., Kamyshinsky R. A., Palamarchuk N. P., Yudina E. B., Nikolskaya E. D., Yabbarov N. G., Mollaeva M. R., Bukreeva T. V. Development of Submicrocapsules Based on Co-Assembled Like-Charged Silica Nanoparticles and Detonation Nanodiamonds and Polyelectrolyte Layers // Pharmaceutics. 2022. Vol. 14. No. 3. p. 575.
Cite this
RIS
Copy
TY - JOUR
DO - 10.3390/pharmaceutics14030575
UR - https://doi.org/10.3390%2Fpharmaceutics14030575
TI - Development of Submicrocapsules Based on Co-Assembled Like-Charged Silica Nanoparticles and Detonation Nanodiamonds and Polyelectrolyte Layers
T2 - Pharmaceutics
AU - Palamarchuk, Konstantin V
AU - Borodina, Tatiana N
AU - Kostenko, Anastasia V
AU - Palamarchuk, Natalya P
AU - Yudina, Elena B
AU - Chesnokov, Yu.M.
AU - Kamyshinsky, Roman A.
AU - Nikolskaya, Elena D
AU - Yabbarov, Nikita G
AU - Mollaeva, Mariia R
AU - Bukreeva, Tatiana V
PY - 2022
DA - 2022/03/05 00:00:00
PB - Multidisciplinary Digital Publishing Institute (MDPI)
SP - 575
IS - 3
VL - 14
PMID - 35335951
SN - 1999-4923
ER -
Cite this
BibTex
Copy
@article{2022_Palamarchuk,
author = {Konstantin V Palamarchuk and Tatiana N Borodina and Anastasia V Kostenko and Natalya P Palamarchuk and Elena B Yudina and Yu.M. Chesnokov and Roman A. Kamyshinsky and Elena D Nikolskaya and Nikita G Yabbarov and Mariia R Mollaeva and Tatiana V Bukreeva},
title = {Development of Submicrocapsules Based on Co-Assembled Like-Charged Silica Nanoparticles and Detonation Nanodiamonds and Polyelectrolyte Layers},
journal = {Pharmaceutics},
year = {2022},
volume = {14},
publisher = {Multidisciplinary Digital Publishing Institute (MDPI)},
month = {mar},
url = {https://doi.org/10.3390%2Fpharmaceutics14030575},
number = {3},
pages = {575},
doi = {10.3390/pharmaceutics14030575}
}
Cite this
MLA
Copy
Palamarchuk, Konstantin V., et al. “Development of Submicrocapsules Based on Co-Assembled Like-Charged Silica Nanoparticles and Detonation Nanodiamonds and Polyelectrolyte Layers.” Pharmaceutics, vol. 14, no. 3, Mar. 2022, p. 575. https://doi.org/10.3390%2Fpharmaceutics14030575.