Open Access
Polyelectrolyte Complexes of Natural Polymers and Their Biomedical Applications
Publication type: Journal Article
Publication date: 2019-04-12
PubMed ID:
31013742
General Chemistry
Polymers and Plastics
Abstract
Polyelectrolyte complexes (PECs), composed of natural and biodegradable polymers, (such as positively charged chitosan or protamine and negatively charged glycosaminoglycans (GAGs)) have attracted attention as hydrogels, films, hydrocolloids, and nano-/micro-particles (N/MPs) for biomedical applications. This is due to their biocompatibility and biological activities. These PECs have been used as drug and cell delivery carriers, hemostats, wound dressings, tissue adhesives, and scaffolds for tissue engineering. In addition to their comprehensive review, this review describes our original studies and provides an overview of the characteristics of chitosan-based hydrogel, including photo-cross-linkable chitosan hydrogel and hydrocolloidal PECs, as well as molecular-weight heparin (LH)/positively charged protamine (P) N/MPs. These are generated by electrostatic interactions between negatively charged LH and positively charged P together with their potential biomedical applications.
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Metrics
108
Total citations:
108
Citations from 2025:
21
(19.44%)
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GOST
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Ishihara M. et al. Polyelectrolyte Complexes of Natural Polymers and Their Biomedical Applications // Polymers. 2019. Vol. 11. No. 4. p. 672.
GOST all authors (up to 50)
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Ishihara M., Kishimoto S., NAKAMURA S., Sato Y., Hattori H. Polyelectrolyte Complexes of Natural Polymers and Their Biomedical Applications // Polymers. 2019. Vol. 11. No. 4. p. 672.
Cite this
RIS
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TY - JOUR
DO - 10.3390/polym11040672
UR - https://doi.org/10.3390/polym11040672
TI - Polyelectrolyte Complexes of Natural Polymers and Their Biomedical Applications
T2 - Polymers
AU - Ishihara, Masayuki
AU - Kishimoto, Satoko
AU - NAKAMURA, Shingo
AU - Sato, Yoko
AU - Hattori, Hidemi
PY - 2019
DA - 2019/04/12
PB - MDPI
SP - 672
IS - 4
VL - 11
PMID - 31013742
SN - 2073-4360
ER -
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BibTex (up to 50 authors)
Copy
@article{2019_Ishihara,
author = {Masayuki Ishihara and Satoko Kishimoto and Shingo NAKAMURA and Yoko Sato and Hidemi Hattori},
title = {Polyelectrolyte Complexes of Natural Polymers and Their Biomedical Applications},
journal = {Polymers},
year = {2019},
volume = {11},
publisher = {MDPI},
month = {apr},
url = {https://doi.org/10.3390/polym11040672},
number = {4},
pages = {672},
doi = {10.3390/polym11040672}
}
Cite this
MLA
Copy
Ishihara, Masayuki, et al. “Polyelectrolyte Complexes of Natural Polymers and Their Biomedical Applications.” Polymers, vol. 11, no. 4, Apr. 2019, p. 672. https://doi.org/10.3390/polym11040672.