Open Access
Polymers, volume 14, issue 12, pages 2444
Antiseptic Polymer–Surfactant Complexes with Long-Lasting Activity against SARS-CoV-2
Shibaev Andrey V
1
,
Karamov Eduard
2, 3
,
Larichev Viktor F
2
,
Kornilaeva Galina V.
2
,
Fedyakina Irina T
2
,
Turgiev Ali S
2, 3
,
Philippova O.E.
1
,
Publication type: Journal Article
Publication date: 2022-06-16
PubMed ID:
35746017
General Chemistry
Polymers and Plastics
Abstract
Antiseptic polymer gel–surfactant complexes were prepared by incorporating the low-molecular-weight cationic disinfectant cetylpyridinium chloride into the oppositely charged, slightly cross-linked polymer matrices. Three types of polymers were used: copolymers of acrylamide and sodium 2-acrylamido-2-methylpropane sulfonate; copolymers of acrylamide and sodium methacrylate; copolymers of vinylpyrrolidone and sodium methacrylate. It was shown that the rate of the release of the cationic disinfectant from the oppositely charged polymer gels could be tuned in a fairly broad range by varying the concentration of the disinfectant, the degree of swelling, and degree of cross-linking of the gel and the content/type of anionic repeat units in the polymer matrix. Polymer–surfactant complexes were demonstrated to reduce SARS-CoV-2 titer by seven orders of magnitude in as little as 5 s. The complexes retained strong virucidal activity against SARS-CoV-2 for at least one week.
Citations by journals
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1
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Gels
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Gels
1 publication, 20%
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Macromolecular Chemistry and Physics
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Macromolecular Chemistry and Physics
1 publication, 20%
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Polymers
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Polymers
1 publication, 20%
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International Journal of Molecular Sciences
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International Journal of Molecular Sciences
1 publication, 20%
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Polymer Science - Series A
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Polymer Science - Series A
1 publication, 20%
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1
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Citations by publishers
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1
2
3
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|
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Multidisciplinary Digital Publishing Institute (MDPI)
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Multidisciplinary Digital Publishing Institute (MDPI)
3 publications, 60%
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Wiley
|
Wiley
1 publication, 20%
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Pleiades Publishing
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Pleiades Publishing
1 publication, 20%
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1
2
3
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- We do not take into account publications that without a DOI.
- Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
- Statistics recalculated weekly.
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Molchanov V. S. et al. Antiseptic Polymer–Surfactant Complexes with Long-Lasting Activity against SARS-CoV-2 // Polymers. 2022. Vol. 14. No. 12. p. 2444.
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Molchanov V. S., Shibaev A. V., Karamov E., Larichev V. F., Kornilaeva G. V., Fedyakina I. T., Turgiev A. S., Philippova O., Khokhlov A. R. Antiseptic Polymer–Surfactant Complexes with Long-Lasting Activity against SARS-CoV-2 // Polymers. 2022. Vol. 14. No. 12. p. 2444.
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TY - JOUR
DO - 10.3390/polym14122444
UR - https://doi.org/10.3390%2Fpolym14122444
TI - Antiseptic Polymer–Surfactant Complexes with Long-Lasting Activity against SARS-CoV-2
T2 - Polymers
AU - Larichev, Viktor F
AU - Kornilaeva, Galina V.
AU - Fedyakina, Irina T
AU - Turgiev, Ali S
AU - Khokhlov, Alexei R.
AU - Molchanov, Vyacheslav S
AU - Shibaev, Andrey V
AU - Karamov, Eduard
AU - Philippova, O.E.
PY - 2022
DA - 2022/06/16 00:00:00
PB - Multidisciplinary Digital Publishing Institute (MDPI)
SP - 2444
IS - 12
VL - 14
PMID - 35746017
SN - 2073-4360
ER -
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@article{2022_Molchanov,
author = {Viktor F Larichev and Galina V. Kornilaeva and Irina T Fedyakina and Ali S Turgiev and Alexei R. Khokhlov and Vyacheslav S Molchanov and Andrey V Shibaev and Eduard Karamov and O.E. Philippova},
title = {Antiseptic Polymer–Surfactant Complexes with Long-Lasting Activity against SARS-CoV-2},
journal = {Polymers},
year = {2022},
volume = {14},
publisher = {Multidisciplinary Digital Publishing Institute (MDPI)},
month = {jun},
url = {https://doi.org/10.3390%2Fpolym14122444},
number = {12},
pages = {2444},
doi = {10.3390/polym14122444}
}
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Molchanov, Vyacheslav S., et al. “Antiseptic Polymer–Surfactant Complexes with Long-Lasting Activity against SARS-CoV-2.” Polymers, vol. 14, no. 12, Jun. 2022, p. 2444. https://doi.org/10.3390%2Fpolym14122444.