Open Access
Nanomaterial Delivery Systems for mRNA Vaccines
MICHAEL D. BUSCHMANN
1
,
Manuel J Carrasco
1
,
Suman Alishetty
1
,
Mikell Paige
2
,
Mohamad-Gabriel Alameh
3
,
Drew Weissman
4
Publication type: Journal Article
Publication date: 2021-01-19
PubMed ID:
33478109
Drug Discovery
Pharmacology
Infectious Diseases
Pharmacology (medical)
Immunology
Abstract
The recent success of mRNA vaccines in SARS-CoV-2 clinical trials is in part due to the development of lipid nanoparticle delivery systems that not only efficiently express the mRNA-encoded immunogen after intramuscular injection, but also play roles as adjuvants and in vaccine reactogenicity. We present an overview of mRNA delivery systems and then focus on the lipid nanoparticles used in the current SARS-CoV-2 vaccine clinical trials. The review concludes with an analysis of the determinants of the performance of lipid nanoparticles in mRNA vaccines.
Found
Nothing found, try to update filter.
Found
Nothing found, try to update filter.
Top-30
Journals
|
2
4
6
8
10
12
14
16
|
|
|
Vaccines
16 publications, 3.5%
|
|
|
Pharmaceutics
15 publications, 3.28%
|
|
|
Molecular Pharmaceutics
12 publications, 2.63%
|
|
|
International Journal of Pharmaceutics
11 publications, 2.41%
|
|
|
Journal of Controlled Release
9 publications, 1.97%
|
|
|
ACS Nano
9 publications, 1.97%
|
|
|
Frontiers in Immunology
8 publications, 1.75%
|
|
|
npj Vaccines
8 publications, 1.75%
|
|
|
Advanced Drug Delivery Reviews
8 publications, 1.75%
|
|
|
Advanced Functional Materials
7 publications, 1.53%
|
|
|
RNA Technologies
7 publications, 1.53%
|
|
|
Advanced Materials
6 publications, 1.31%
|
|
|
Journal of the American Chemical Society
6 publications, 1.31%
|
|
|
Nature Communications
5 publications, 1.09%
|
|
|
Frontiers in Bioengineering and Biotechnology
5 publications, 1.09%
|
|
|
Journal of Nanobiotechnology
5 publications, 1.09%
|
|
|
Journal of Materials Chemistry B
4 publications, 0.88%
|
|
|
Signal Transduction and Targeted Therapy
4 publications, 0.88%
|
|
|
Nano Research
4 publications, 0.88%
|
|
|
Journal of Drug Delivery Science and Technology
4 publications, 0.88%
|
|
|
Nano Today
4 publications, 0.88%
|
|
|
Biomaterials Science
4 publications, 0.88%
|
|
|
Advanced Science
4 publications, 0.88%
|
|
|
Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology
4 publications, 0.88%
|
|
|
International Journal of Molecular Sciences
3 publications, 0.66%
|
|
|
Viruses
3 publications, 0.66%
|
|
|
Pharmaceuticals
3 publications, 0.66%
|
|
|
Scientific Reports
3 publications, 0.66%
|
|
|
Journal of Pharmaceutical Sciences
3 publications, 0.66%
|
|
|
2
4
6
8
10
12
14
16
|
Publishers
|
20
40
60
80
100
120
|
|
|
Elsevier
112 publications, 24.51%
|
|
|
Springer Nature
83 publications, 18.16%
|
|
|
MDPI
58 publications, 12.69%
|
|
|
Wiley
52 publications, 11.38%
|
|
|
American Chemical Society (ACS)
44 publications, 9.63%
|
|
|
Frontiers Media S.A.
23 publications, 5.03%
|
|
|
Taylor & Francis
16 publications, 3.5%
|
|
|
Royal Society of Chemistry (RSC)
12 publications, 2.63%
|
|
|
Cold Spring Harbor Laboratory
11 publications, 2.41%
|
|
|
Bentham Science Publishers Ltd.
4 publications, 0.88%
|
|
|
American Association for the Advancement of Science (AAAS)
3 publications, 0.66%
|
|
|
Science in China Press
3 publications, 0.66%
|
|
|
Cambridge University Press
2 publications, 0.44%
|
|
|
IntechOpen
2 publications, 0.44%
|
|
|
Pharmaceutical Society of Japan
1 publication, 0.22%
|
|
|
World Scientific
1 publication, 0.22%
|
|
|
Han-Gug Misaengmul Hag-hoe/The Microbiological Society of Korea
1 publication, 0.22%
|
|
|
SAGE
1 publication, 0.22%
|
|
|
Shenyang Pharmaceutical University
1 publication, 0.22%
|
|
|
International Research and Cooperation Association for Bio & Socio-Sciences Advancement (IRCA-BSSA)
1 publication, 0.22%
|
|
|
Farmaceutsko Drustvo Srbije
1 publication, 0.22%
|
|
|
American Institute of Mathematical Sciences (AIMS)
1 publication, 0.22%
|
|
|
Annual Reviews
1 publication, 0.22%
|
|
|
Institute of Electrical and Electronics Engineers (IEEE)
1 publication, 0.22%
|
|
|
IOP Publishing
1 publication, 0.22%
|
|
|
Walter de Gruyter
1 publication, 0.22%
|
|
|
Proceedings of the National Academy of Sciences (PNAS)
1 publication, 0.22%
|
|
|
OOO Zhurnal "Mendeleevskie Soobshcheniya"
1 publication, 0.22%
|
|
|
Research Square Platform LLC
1 publication, 0.22%
|
|
|
20
40
60
80
100
120
|
- We do not take into account publications without a DOI.
- Statistics recalculated weekly.
Are you a researcher?
Create a profile to get free access to personal recommendations for colleagues and new articles.
Metrics
457
Total citations:
457
Citations from 2025:
89
(19.47%)
Cite this
GOST |
RIS |
BibTex |
MLA
Cite this
GOST
Copy
BUSCHMANN M. D. et al. Nanomaterial Delivery Systems for mRNA Vaccines // Vaccines. 2021. Vol. 9. No. 1. p. 65.
GOST all authors (up to 50)
Copy
BUSCHMANN M. D., Carrasco M. J., Alishetty S., Paige M., Alameh M., Weissman D. Nanomaterial Delivery Systems for mRNA Vaccines // Vaccines. 2021. Vol. 9. No. 1. p. 65.
Cite this
RIS
Copy
TY - JOUR
DO - 10.3390/vaccines9010065
UR - https://doi.org/10.3390/vaccines9010065
TI - Nanomaterial Delivery Systems for mRNA Vaccines
T2 - Vaccines
AU - BUSCHMANN, MICHAEL D.
AU - Carrasco, Manuel J
AU - Alishetty, Suman
AU - Paige, Mikell
AU - Alameh, Mohamad-Gabriel
AU - Weissman, Drew
PY - 2021
DA - 2021/01/19
PB - MDPI
SP - 65
IS - 1
VL - 9
PMID - 33478109
SN - 2076-393X
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2021_BUSCHMANN,
author = {MICHAEL D. BUSCHMANN and Manuel J Carrasco and Suman Alishetty and Mikell Paige and Mohamad-Gabriel Alameh and Drew Weissman},
title = {Nanomaterial Delivery Systems for mRNA Vaccines},
journal = {Vaccines},
year = {2021},
volume = {9},
publisher = {MDPI},
month = {jan},
url = {https://doi.org/10.3390/vaccines9010065},
number = {1},
pages = {65},
doi = {10.3390/vaccines9010065}
}
Cite this
MLA
Copy
BUSCHMANN, MICHAEL D., et al. “Nanomaterial Delivery Systems for mRNA Vaccines.” Vaccines, vol. 9, no. 1, Jan. 2021, p. 65. https://doi.org/10.3390/vaccines9010065.