Open Access
An effective one-pot access to polynuclear dispiroheterocyclic structures comprising pyrrolidinyloxindole and imidazothiazolotriazine moieties via a 1,3-dipolar cycloaddition strategy
Natalya V Sigay
1
,
Sergei A Serkov
1
,
Valentina A Karnoukhova
2
,
Vadim V. Kachala
1
,
Alexander S. Shashkov
1
,
Igor E Zanin
3
,
Nina N. Makhova
1
Publication type: Journal Article
Publication date: 2016-10-24
scimago Q2
wos Q3
SJR: 0.482
CiteScore: 3.8
Impact factor: 2.1
ISSN: 18605397
PubMed ID:
28144290
Organic Chemistry
Abstract
An effective and highly regio- and diastereoselective one-pot method for the synthesis of new polynuclear dispiroheterocyclic systems with five stereogenic centers (dispiro[imidazo[4,5-e]thiazolo[3,2-b]-1,2,4-triazine-6,3′-pyrrolidine-2′,3′′-indoles]) comprising pyrrolidinyloxindole and imidazo[4,5-e]thiazolo[3,2-b]-1,2,4-triazine moieties has been developed. The method relies on a 1,3-dipolar cycloaddition of azomethine ylides generated in situ from isatin derivatives and sarcosine to 6-benzylideneimidazo[4,5-e]thiazolo[3,2-b]-1,2,4-triazine-2,7-diones.
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Total citations:
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Citations from 2024:
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Izmestev A. N. et al. An effective one-pot access to polynuclear dispiroheterocyclic structures comprising pyrrolidinyloxindole and imidazothiazolotriazine moieties via a 1,3-dipolar cycloaddition strategy // Beilstein Journal of Organic Chemistry. 2016. Vol. 12. pp. 2240-2249.
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Izmestev A. N., Gazieva G. A., Sigay N. V., Serkov S. A., Karnoukhova V. A., Kachala V. V., Shashkov A. S., Zanin I. E., Kravchenko A. N., Makhova N. N. An effective one-pot access to polynuclear dispiroheterocyclic structures comprising pyrrolidinyloxindole and imidazothiazolotriazine moieties via a 1,3-dipolar cycloaddition strategy // Beilstein Journal of Organic Chemistry. 2016. Vol. 12. pp. 2240-2249.
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TY - JOUR
DO - 10.3762/bjoc.12.216
UR - https://www.beilstein-journals.org/bjoc/articles/12/216
TI - An effective one-pot access to polynuclear dispiroheterocyclic structures comprising pyrrolidinyloxindole and imidazothiazolotriazine moieties via a 1,3-dipolar cycloaddition strategy
T2 - Beilstein Journal of Organic Chemistry
AU - Izmestev, Alexei N
AU - Gazieva, Galina A.
AU - Sigay, Natalya V
AU - Serkov, Sergei A
AU - Karnoukhova, Valentina A
AU - Kachala, Vadim V.
AU - Shashkov, Alexander S.
AU - Zanin, Igor E
AU - Kravchenko, Angelina N.
AU - Makhova, Nina N.
PY - 2016
DA - 2016/10/24
PB - Beilstein-Institut
SP - 2240-2249
VL - 12
PMID - 28144290
SN - 1860-5397
ER -
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BibTex (up to 50 authors)
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@article{2016_Izmestev,
author = {Alexei N Izmestev and Galina A. Gazieva and Natalya V Sigay and Sergei A Serkov and Valentina A Karnoukhova and Vadim V. Kachala and Alexander S. Shashkov and Igor E Zanin and Angelina N. Kravchenko and Nina N. Makhova},
title = {An effective one-pot access to polynuclear dispiroheterocyclic structures comprising pyrrolidinyloxindole and imidazothiazolotriazine moieties via a 1,3-dipolar cycloaddition strategy},
journal = {Beilstein Journal of Organic Chemistry},
year = {2016},
volume = {12},
publisher = {Beilstein-Institut},
month = {oct},
url = {https://www.beilstein-journals.org/bjoc/articles/12/216},
pages = {2240--2249},
doi = {10.3762/bjoc.12.216}
}