Open Access
Beilstein Journal of Organic Chemistry, volume 12, pages 2240-2249
An effective one-pot access to polynuclear dispiroheterocyclic structures comprising pyrrolidinyloxindole and imidazothiazolotriazine moieties via a 1,3-dipolar cycloaddition strategy
Sigay Natalya V
1
,
Serkov Sergei A
1
,
Karnoukhova Valentina A
2
,
Kachala Vadim V.
1
,
Shashkov Alexander S.
1
,
Zanin Igor E
3
,
Makhova Nina N.
1
Publication type: Journal Article
Publication date: 2016-10-24
Quartile SCImago
Q2
Quartile WOS
Q2
Impact factor: 2.7
ISSN: 18605397
PubMed ID:
28144290
Organic Chemistry
Abstract
An effective and highly regio- and diastereoselective one-pot method for the synthesis of new polynuclear dispiroheterocyclic systems with five stereogenic centers (dispiro[imidazo[4,5-e]thiazolo[3,2-b]-1,2,4-triazine-6,3′-pyrrolidine-2′,3′′-indoles]) comprising pyrrolidinyloxindole and imidazo[4,5-e]thiazolo[3,2-b]-1,2,4-triazine moieties has been developed. The method relies on a 1,3-dipolar cycloaddition of azomethine ylides generated in situ from isatin derivatives and sarcosine to 6-benzylideneimidazo[4,5-e]thiazolo[3,2-b]-1,2,4-triazine-2,7-diones.
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Citations by publishers
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1 publication, 5.26%
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- We do not take into account publications that without a DOI.
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- Statistics recalculated weekly.
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Izmestev A. N. et al. An effective one-pot access to polynuclear dispiroheterocyclic structures comprising pyrrolidinyloxindole and imidazothiazolotriazine moieties via a 1,3-dipolar cycloaddition strategy // Beilstein Journal of Organic Chemistry. 2016. Vol. 12. pp. 2240-2249.
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Izmestev A. N., Gazieva G. A., Sigay N. V., Serkov S. A., Karnoukhova V. A., Kachala V. V., Shashkov A. S., Zanin I. E., Kravchenko A. N., Makhova N. N. An effective one-pot access to polynuclear dispiroheterocyclic structures comprising pyrrolidinyloxindole and imidazothiazolotriazine moieties via a 1,3-dipolar cycloaddition strategy // Beilstein Journal of Organic Chemistry. 2016. Vol. 12. pp. 2240-2249.
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TY - JOUR
DO - 10.3762/bjoc.12.216
UR - https://doi.org/10.3762%2Fbjoc.12.216
TI - An effective one-pot access to polynuclear dispiroheterocyclic structures comprising pyrrolidinyloxindole and imidazothiazolotriazine moieties via a 1,3-dipolar cycloaddition strategy
T2 - Beilstein Journal of Organic Chemistry
AU - Izmestev, Alexei N
AU - Gazieva, Galina A.
AU - Sigay, Natalya V
AU - Serkov, Sergei A
AU - Karnoukhova, Valentina A
AU - Kachala, Vadim V.
AU - Shashkov, Alexander S.
AU - Zanin, Igor E
AU - Kravchenko, Angelina N.
AU - Makhova, Nina N.
PY - 2016
DA - 2016/10/24 00:00:00
PB - Beilstein-Institut
SP - 2240-2249
VL - 12
PMID - 28144290
SN - 1860-5397
ER -
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@article{2016_Izmestev,
author = {Alexei N Izmestev and Galina A. Gazieva and Natalya V Sigay and Sergei A Serkov and Valentina A Karnoukhova and Vadim V. Kachala and Alexander S. Shashkov and Igor E Zanin and Angelina N. Kravchenko and Nina N. Makhova},
title = {An effective one-pot access to polynuclear dispiroheterocyclic structures comprising pyrrolidinyloxindole and imidazothiazolotriazine moieties via a 1,3-dipolar cycloaddition strategy},
journal = {Beilstein Journal of Organic Chemistry},
year = {2016},
volume = {12},
publisher = {Beilstein-Institut},
month = {oct},
url = {https://doi.org/10.3762%2Fbjoc.12.216},
pages = {2240--2249},
doi = {10.3762/bjoc.12.216}
}