Heterotypic 3D models of human breast and brain tumors for the study of tumor-stroma interaction and the development of new therapeutic approaches

  1. Cell and tissue culture
  2. In vitro tumor models: primary and conventional tumor cell cultures, tissue spheroids
  3. Confocal microscopy
Anna Nushtaeva 🥼 🤝
Scientific supervisor

Research directions

Heterotypic 3D models of human breast and brain tumors for the study of tumor-stroma interaction and the development of new therapeutic approaches

+
Heterogeneous microenvironment, including breast tumors and glioblastomas, affects the progression and drug resistance of the tumor. Immunotherapy with oncolytic viruses(s) and immune cells is a promising treatment strategy. Heterotypic 3D models in vitro will allow detailed investigation of the interactions of tumor cells and its microenvironment and will serve as a platform for testing effective therapeutic approaches based on VV-GMCSF-Lac and NK cells.

Publications and patents

Partners

Lab address

Олимпийский просп., 1, Сочи, Краснодарский край
Authorization required.