Laboratory of Biophysical Chemistry

Molecular modeling Physical Chemistry Biophysics

R-36014-0BFB6-ER78O

Head of Laboratory

Sedov, Igor A

DSc in Chemistry, Associate Professor

Publications

100

Citations

1 312

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Lab website

Studies of protein-protein, protein-ligand interactions, processes of denaturation and aggregation of proteins using theoretical and experimental methods to study the structure and solvation properties of ionic liquids, thermodynamics of hydrophobic and solvophobic effects

Molecular dynamics and quantum chemical calculations
NMR spectroscopy of liquids (1D, 2D, 3D);
Spectrophotometry
IR spectroscopy
Molecular docking
UV spectroscopy
Fluorescence Spectroscopy
Differential Scanning Calorimetry (DSC)
Atomic Force Microscopy (AFM)
Gas chromatography

Igor Sedov 🥼 🤝

Head of Laboratory

Timur Magsumov

Researcher

Research directions

Properties of proton ionic liquids as promising solvents

Study of the relationship between the structure of ions, the nanostructure of the liquid phase and the solvation and thermochemical properties of ionic liquids

Molecular mechanisms of amyloid formation and antiamyloid activity

Studies of the process of protein aggregation with the formation of amyloid structures associated with a number of incurable neurodegenerative diseases, including Alzheimer's disease. Studies of the mechanism of action of compounds with the ability to inhibit amyloid formation and the relationship between their structure and activity. Search and directional design of amyloid structure indicators for diagnostic purposes.