Introducing tox-Profiles of Chemical Reactions.
Publication type: Journal Article
Publication date: 2020-10-01
scimago Q1
wos Q1
SJR: 5.550
CiteScore: 27.6
Impact factor: 16.9
ISSN: 14337851, 15213773
PubMed ID:
33002316
General Chemistry
Catalysis
Abstract
In this Essay, we present a critical analysis of two common practices in modern chemistry-that is, of using speculations about the "greenness" and "nontoxicity" of developed synthesis procedures and of a priori labelling various compounds derived from natural sources as being environmentally safe. We note that every organic molecule that contains functional groups should be biologically active. Thus, analysis of the particular greenness and the potential environmental impact of a given chemical process should account for the biological activity of all its components in a measureable (rather than empirical) way. We highlight the necessity of clarifying discussions on biological activity and toxicity and propose possible ways of introducing tox-Profiles as a reliable overview of the overall toxicity of chemical reactions.
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26
Total citations:
26
Citations from 2025:
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(11.54%)
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GOST
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Egorova K. S., Galushko A. S., Ananikov V. P. Introducing tox-Profiles of Chemical Reactions. // Angewandte Chemie - International Edition. 2020. Vol. 59. No. 50. pp. 22296-22305.
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Egorova K. S., Galushko A. S., Ananikov V. P. Introducing tox-Profiles of Chemical Reactions. // Angewandte Chemie - International Edition. 2020. Vol. 59. No. 50. pp. 22296-22305.
Cite this
RIS
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TY - JOUR
DO - 10.1002/anie.202003082
UR - https://doi.org/10.1002/anie.202003082
TI - Introducing tox-Profiles of Chemical Reactions.
T2 - Angewandte Chemie - International Edition
AU - Egorova, Ksenia S
AU - Galushko, Alexey S
AU - Ananikov, Valentine P.
PY - 2020
DA - 2020/10/01
PB - Wiley
SP - 22296-22305
IS - 50
VL - 59
PMID - 33002316
SN - 1433-7851
SN - 1521-3773
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2020_Egorova,
author = {Ksenia S Egorova and Alexey S Galushko and Valentine P. Ananikov},
title = {Introducing tox-Profiles of Chemical Reactions.},
journal = {Angewandte Chemie - International Edition},
year = {2020},
volume = {59},
publisher = {Wiley},
month = {oct},
url = {https://doi.org/10.1002/anie.202003082},
number = {50},
pages = {22296--22305},
doi = {10.1002/anie.202003082}
}
Cite this
MLA
Copy
Egorova, Ksenia S., et al. “Introducing tox-Profiles of Chemical Reactions..” Angewandte Chemie - International Edition, vol. 59, no. 50, Oct. 2020, pp. 22296-22305. https://doi.org/10.1002/anie.202003082.