Topics in Current Chemistry, pages 127-195
ANGUCYCLINES : TOTAL SYNTHESES, NEW STRUCTURES, AND BIOSYNTHETIC STUDIES OF AN EMERGING NEW CLASS OF ANTIBIOTICS
Karsten Krohn
1
,
Jürgen Rohr
2
Publication type: Book Chapter
Publication date: 1997-01-01
Journal:
Topics in Current Chemistry
scimago Q1
wos Q1
SJR: 1.260
CiteScore: 13.7
Impact factor: 7.1
ISSN: 03401022, 23650869, 23648961
Abstract
General and recent aspects of chemical syntheses on angucyclinones and selected related natural products are summarized here. In the first part of this review on angucyclines, the chemical reaction used as a key step for the construction of the angucyclinone frame is discussed. In the second part, new members of the angucycline group of antibiotics, their bioactivity and recent biosynthetic studies including modern aspects of molecular biology (genetics) are reviewed.
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