A Facile Method of Preparation of Polymer-Stabilized Perfluorocarbon Nanoparticles with Enhanced Contrast for Molecular Magnetic Resonance Imaging

Gervits L.L., Shibaev A.V., Gulyaev M.V., Molchanov V.S., Anisimov N.V., Pirogov Y.A., Khokhlov A.R., Philippova O.E.
Тип документаJournal Article
Дата публикации2017-09-01
Название журналаBioNanoScience
ИздательSpringer Nature
Квартиль по SCImagoQ3
Квартиль по Web of Science
Импакт-фактор 2021
ISSN21911630, 21911649
Bioengineering
Biomedical Engineering
Краткое описание
We present a new efficient method of incorporation of gadolinium chelates into polymeric shell surrounding liquid nanoparticles of perfluorotributylamine, which does not degrade the particles stability. The payload reaches ca. 105 Gd ions per nanoparticle giving large local concentration of contrast agent. The relaxivity of Gd-loaded nanoparticles estimated by magnetic resonance imaging at 7 T magnetic field is as high as 105–106 mM−1 s−1. These nanoparticles are promising for dual-mode imaging simultaneously on two nuclei 1H and 19F, thus enhancing the quality of visualization.
Пристатейные ссылки: 35
Цитируется в публикациях: 8
Ion-Specific Self-Assembly of Hydrophobically Modified Polycation of Natural Origin
Korchagina E.V., Philippova O.E.
Q1 Macromolecules 2015 цитирований: 9
Using lanthanide ions in molecular bioimaging
Amoroso A.J., Pope S.J.
Q1 Chemical Society Reviews 2015 цитирований: 250
Perfluorocarbon Nanoparticles: Evolution of a Multimodality and Multifunctional Imaging Agent
Winter P.M.
Q2 Scientifica 2014 цитирований: 9
Open Access
Open access
Relaxometric studies of gadolinium-functionalized perfluorocarbon nanoparticles for MR imaging
de Vries A., Moonen R., Yildirim M., Langereis S., Lamerichs R., Pikkemaat J.A., Baroni S., Terreno E., Nicolay K., Strijkers G.J., Grüll H.
Q2 Contrast Media and Molecular Imaging 2014 цитирований: 22
Open Access
Open access
Relaxivity Enhancement in Macromolecular and Nanosized GdIII-Based MRI Contrast Agents
Botta M., Tei L.
Q2 European Journal of Inorganic Chemistry 2012 цитирований: 150
Characterization of MRI contrast agent-loaded polymeric nanocapsules as versatile vehicle for targeted imaging
Sharma S., Paiphansiri U., Hombach V., Mailänder V., Zimmermann O., Landfester K., Rasche V.
Q2 Contrast Media and Molecular Imaging 2010 цитирований: 3
Open Access
Open access
19F MRI for quantitative in vivo cell tracking
Srinivas M., Heerschap A., Ahrens E.T., Figdor C.G., Vries I.J.
Q1 Trends in Biotechnology 2010 цитирований: 201
Early Assessment of Pulmonary Inflammation by 19 F MRI In Vivo
Ebner B., Behm P., Jacoby C., Burghoff S., French B.A., Schrader J., Flögel U.
Q1 Circulation: Cardiovascular Imaging 2010 цитирований: 89
Primer on gadolinium chemistry
Sherry A.D., Caravan P., Lenkinski R.E.
Q1 Journal of Magnetic Resonance Imaging 2009 цитирований: 258
Magnetic resonance imaging of multifunctional pluronic stabilized iron-oxide nanoparticles in tumor-bearing mice
Jain T.K., Foy S.P., Erokwu B., Dimitrijevic S., Flask C.A., Labhasetwar V.
Q1 Biomaterials 2009 цитирований: 105
Open Access
Open access
Stability of emulsions for parenteral feeding: Preparation and characterization of o/w nanoemulsions with natural oils and Pluronic f68 as surfactant
Wulff-Pérez M., Torcello-Gómez A., Gálvez-Ruíz M.J., Martín-Rodríguez A.
Q1 Food Hydrocolloids 2009 цитирований: 113
Perfluorocarbon Nanoemulsions for Quantitative Molecular Imaging and Targeted Therapeutics
Kaneda M.M., Caruthers S., Lanza G.M., Wickline S.A.
Q2 Annals of Biomedical Engineering 2009 цитирований: 122
Gadolinium-modulated19F signals from perfluorocarbon nanoparticles as a new strategy for molecular imaging
Neubauer A.M., Myerson J., Caruthers S.D., Hockett F.D., Winter P.M., Chen J., Gaffney P.J., Robertson J.D., Lanza G.M., Wickline S.A.
Q1 Magnetic Resonance in Medicine 2008 цитирований: 74
Метрики
Поделиться
Цитировать
ГОСТ |
Цитировать
1. Gervits L.L. и др. A Facile Method of Preparation of Polymer-Stabilized Perfluorocarbon Nanoparticles with Enhanced Contrast for Molecular Magnetic Resonance Imaging // BioNanoScience. 2017. Т. 7. № 3. С. 456–463.
RIS |
Цитировать

TY - JOUR

DO - 10.1007/s12668-017-0400-8

UR - http://dx.doi.org/10.1007/s12668-017-0400-8

TI - A Facile Method of Preparation of Polymer-Stabilized Perfluorocarbon Nanoparticles with Enhanced Contrast for Molecular Magnetic Resonance Imaging

T2 - BioNanoScience

AU - Gervits, Lev L.

AU - Shibaev, Andrey V.

AU - Gulyaev, Mikhail V.

AU - Molchanov, Vyacheslav S.

AU - Anisimov, Nikolai V.

AU - Pirogov, Yury A.

AU - Khokhlov, Alexei R.

AU - Philippova, Olga E.

PY - 2017

DA - 2017/02/23

PB - Springer Science and Business Media LLC

SP - 456-463

IS - 3

VL - 7

SN - 2191-1630

SN - 2191-1649

ER -

BibTex |
Цитировать

@article{2017,

doi = {10.1007/s12668-017-0400-8},

url = {https://doi.org/10.1007%2Fs12668-017-0400-8},

year = 2017,

month = {feb},

publisher = {Springer Science and Business Media {LLC}},

volume = {7},

number = {3},

pages = {456--463},

author = {Lev L. Gervits and Andrey V. Shibaev and Mikhail V. Gulyaev and Vyacheslav S. Molchanov and Nikolai V. Anisimov and Yury A. Pirogov and Alexei R. Khokhlov and Olga E. Philippova},

title = {A Facile Method of Preparation of Polymer-Stabilized Perfluorocarbon Nanoparticles with Enhanced Contrast for Molecular Magnetic Resonance Imaging}

}

MLA
Цитировать
Gervits, Lev L. et al. “A Facile Method of Preparation of Polymer-Stabilized Perfluorocarbon Nanoparticles with Enhanced Contrast for Molecular Magnetic Resonance Imaging.” BioNanoScience 7.3 (2017): 456–463. Crossref. Web.