Biomimetic sequence design in functional copolymers

We review recent studies on the methods of design of sequences in synthetic copolymers aimed to achieve given functional properties. Our approach is biomimetic in the sense that we have as an example some functional features of biopolymers (such as solubility of globules or selectivity in complex formation with a substrate). In particular, the methods to obtain so-called proteinlike copolymers (which give soluble globules with core-shell structure) and molecular dispensers (which are able to absorb selectively nanoparticles of a given size) are discussed. The problems of evolution of sequences in copolymers are considered from the viewpoint of emerging of information complexity in the sequences in the course of this evolution.