Carboxylated multiwalled carbon nanotubes based biosensor for aflatoxin detection
Chandan Singh
1
,
Saurabh Srivastava
2, 3
,
Md. Azahar Ali
1
,
Tejendra Kumar Gupta
4
,
G. Sumana
1
,
Anchal Srivastava
5
,
R. B. Mathur
4
,
Bansi D. Malhotra
3, 6
Publication type: Journal Article
Publication date: 2013-08-01
wos Q1
SJR: —
CiteScore: —
Impact factor: 7.7
ISSN: 09254005
Materials Chemistry
Metals and Alloys
Surfaces, Coatings and Films
Electronic, Optical and Magnetic Materials
Condensed Matter Physics
Electrical and Electronic Engineering
Instrumentation
Abstract
We report results of studies relating to the development of an electrochemical immunosensor based on carboxylated multiwalled carbon nanotubes (c-MWCNTs) electrophoretically deposited onto indium tin oxide (ITO) glass. This c-MWCNTs/ITO electrode surface has been functionalized with monoclonal aflatoxin B1 antibodies (anti-AFB1) for the detection of aflatoxin-B1 using electrochemical technique. Electron microscopy, X-ray diffraction and Raman studies suggest successful synthesis of c-MWCNTs and the Fourier transform infra-red spectroscopic (FT-IR) studies reveal its carboxylic functionalized nature. The proposed immunosensor shows high sensitivity (95.2 μA ng−1 mL cm−2), improved detection limit (0.08 ng mL−1) in the linear detection range of 0.25–1.375 ng mL−1. The low value of association constant (0.0915 ng mL−1) indicates high affinity of immunoelectrode towards aflatoxin (AFB1).
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145
Total citations:
145
Citations from 2024:
18
(12.42%)
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GOST
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Singh C. et al. Carboxylated multiwalled carbon nanotubes based biosensor for aflatoxin detection // Sensors and Actuators, B: Chemical. 2013. Vol. 185. pp. 258-264.
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Singh C., Srivastava S., Ali M. A., Gupta T. K., Sumana G., Srivastava A., Mathur R. B., Malhotra B. D. Carboxylated multiwalled carbon nanotubes based biosensor for aflatoxin detection // Sensors and Actuators, B: Chemical. 2013. Vol. 185. pp. 258-264.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1016/j.snb.2013.04.040
UR - https://doi.org/10.1016/j.snb.2013.04.040
TI - Carboxylated multiwalled carbon nanotubes based biosensor for aflatoxin detection
T2 - Sensors and Actuators, B: Chemical
AU - Singh, Chandan
AU - Srivastava, Saurabh
AU - Ali, Md. Azahar
AU - Gupta, Tejendra Kumar
AU - Sumana, G.
AU - Srivastava, Anchal
AU - Mathur, R. B.
AU - Malhotra, Bansi D.
PY - 2013
DA - 2013/08/01
PB - Elsevier
SP - 258-264
VL - 185
SN - 0925-4005
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2013_Singh,
author = {Chandan Singh and Saurabh Srivastava and Md. Azahar Ali and Tejendra Kumar Gupta and G. Sumana and Anchal Srivastava and R. B. Mathur and Bansi D. Malhotra},
title = {Carboxylated multiwalled carbon nanotubes based biosensor for aflatoxin detection},
journal = {Sensors and Actuators, B: Chemical},
year = {2013},
volume = {185},
publisher = {Elsevier},
month = {aug},
url = {https://doi.org/10.1016/j.snb.2013.04.040},
pages = {258--264},
doi = {10.1016/j.snb.2013.04.040}
}