Journal of Clinical Microbiology

, volume 58 , issue 7

Multicenter Evaluation of the BioFire FilmArray Pneumonia/Pneumonia Plus Panel for Detection and Quantification of Agents of Lower Respiratory Tract Infection

Caitlin N Murphy ¹

Randal Fowler ¹

Joan-Miquel Balada-Llasat ²

Amanda Carroll ²

Hanna Stone ²

Oluseun Akerele ²

Blake Buchan ³

Sam Windham ³

Amanda Hopp ³

Shira Ronen ³

Ryan F. Relich ⁴

Rebecca Buckner ⁴

Del A Warren ⁴

Romney Humphries ⁵

Shelly Campeau ⁵

Holly Huse ⁵

Suki Chandrasekaran ⁵

Amy Leber ⁶

Kathy Everhart ⁶

Amanda Harrington ⁷

Christina Kwong ⁷

Andrew Bonwit ⁸

Jennifer Dien-Bard ⁸

Samia Naccache ⁸

Cynthia Zimmerman ⁹

Barbara Jones ⁹

Cory Rindlisbacher ¹⁰

Maggie Buccambuso ¹⁰

Angela Clark ¹⁰

Margarita Rogatcheva ¹⁰

Corrin Graue ¹⁰

Kevin M Bourzac ¹⁰

Hide authors affiliations Show authors affiliations: 10 affiliations

University of Nebraska Medical Center, Omaha, Nebraska, USA |

The Ohio State University Wexner Medical Center, Columbus, Ohio, USA |

The Medical College of Wisconsin, Milwaukee, Wisconsin, USA |

⁴

Indiana University School of Medicine, Indianapolis, Indiana, USA |

⁵

UCLA Health, Los Angeles, California, USA |

⁶

Nationwide Children’s Hospital, Columbus, Ohio, USA |

⁷

Loyola University Medical Center, Maywood, Illinois, USA |

⁸

Children’s Hospital of Los Angeles, Los Angeles, California, USA |

⁹

MRIGlobal, Palm Bay, Florida, USA |

¹⁰

BioFire Diagnostics LLC, Salt Lake City, Utah, USA |

Publication type: Journal Article

Publication date: 2020-06-24

American Society for Microbiology

Journal of Clinical Microbiology

scimago Q1

wos Q1

SJR: 1.878

CiteScore: 12.1

Impact factor: 5.4

ISSN: 00951137, 1098660X

DOI: 10.1128/jcm.00128-20

Copy DOI

PubMed ID: 32350043

Microbiology (medical)

Abstract

The ability to provide timely identification of the causative agents of lower respiratory tract infections can promote better patient outcomes and support antimicrobial stewardship efforts. Current diagnostic testing options include culture, molecular testing, and antigen detection. These methods may require collection of various specimens, involve extensive sample treatment, and can suffer from low sensitivity and long turnaround times. This study assessed the performance of the BioFire FilmArray Pneumonia Panel (PN panel) and Pneumonia Plus Panel (PNplus panel), an FDA-cleared sample-to-answer assay that enables the detection of viruses, atypical bacteria, bacteria, and antimicrobial resistance marker genes from lower respiratory tract specimens (sputum and bronchoalveolar lavage [BAL] fluid).

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186

Cite this

GOST |

Cite this

GOST Copy

Murphy C. N. et al. Multicenter Evaluation of the BioFire FilmArray Pneumonia/Pneumonia Plus Panel for Detection and Quantification of Agents of Lower Respiratory Tract Infection // Journal of Clinical Microbiology. 2020. Vol. 58. No. 7.

GOST all authors (up to 50) Copy

Murphy C. N., Fowler R., Balada-Llasat J., Carroll A., Stone H., Akerele O., Buchan B., Windham S., Hopp A., Ronen S., Relich R. F., Buckner R., Warren D. A., Humphries R., Campeau S., Huse H., Chandrasekaran S., Leber A., Everhart K., Harrington A., Kwong C., Bonwit A., Dien-Bard J., Naccache S., Zimmerman C., Jones B., Rindlisbacher C., Buccambuso M., Clark A., Rogatcheva M., Graue C., Bourzac K. M. Multicenter Evaluation of the BioFire FilmArray Pneumonia/Pneumonia Plus Panel for Detection and Quantification of Agents of Lower Respiratory Tract Infection // Journal of Clinical Microbiology. 2020. Vol. 58. No. 7.

RIS |

Cite this

RIS Copy

TY - JOUR

DO - 10.1128/jcm.00128-20

UR - https://doi.org/10.1128/jcm.00128-20

TI - Multicenter Evaluation of the BioFire FilmArray Pneumonia/Pneumonia Plus Panel for Detection and Quantification of Agents of Lower Respiratory Tract Infection

T2 - Journal of Clinical Microbiology

AU - Murphy, Caitlin N

AU - Fowler, Randal

AU - Balada-Llasat, Joan-Miquel

AU - Carroll, Amanda

AU - Stone, Hanna

AU - Akerele, Oluseun

AU - Buchan, Blake

AU - Windham, Sam

AU - Hopp, Amanda

AU - Ronen, Shira

AU - Relich, Ryan F.

AU - Buckner, Rebecca

AU - Warren, Del A

AU - Humphries, Romney

AU - Campeau, Shelly

AU - Huse, Holly

AU - Chandrasekaran, Suki

AU - Leber, Amy

AU - Everhart, Kathy

AU - Harrington, Amanda

AU - Kwong, Christina

AU - Bonwit, Andrew

AU - Dien-Bard, Jennifer

AU - Naccache, Samia

AU - Zimmerman, Cynthia

AU - Jones, Barbara

AU - Rindlisbacher, Cory

AU - Buccambuso, Maggie

AU - Clark, Angela

AU - Rogatcheva, Margarita

AU - Graue, Corrin

AU - Bourzac, Kevin M

PY - 2020

DA - 2020/06/24

PB - American Society for Microbiology

IS - 7

VL - 58

PMID - 32350043

SN - 0095-1137

SN - 1098-660X

ER -

BibTex

Cite this

BibTex (up to 50 authors) Copy

@article{2020_Murphy,

author = {Caitlin N Murphy and Randal Fowler and Joan-Miquel Balada-Llasat and Amanda Carroll and Hanna Stone and Oluseun Akerele and Blake Buchan and Sam Windham and Amanda Hopp and Shira Ronen and Ryan F. Relich and Rebecca Buckner and Del A Warren and Romney Humphries and Shelly Campeau and Holly Huse and Suki Chandrasekaran and Amy Leber and Kathy Everhart and Amanda Harrington and Christina Kwong and Andrew Bonwit and Jennifer Dien-Bard and Samia Naccache and Cynthia Zimmerman and Barbara Jones and Cory Rindlisbacher and Maggie Buccambuso and Angela Clark and Margarita Rogatcheva and Corrin Graue and Kevin M Bourzac},

title = {Multicenter Evaluation of the BioFire FilmArray Pneumonia/Pneumonia Plus Panel for Detection and Quantification of Agents of Lower Respiratory Tract Infection},

journal = {Journal of Clinical Microbiology},

year = {2020},

volume = {58},

publisher = {American Society for Microbiology},

month = {jun},

url = {https://doi.org/10.1128/jcm.00128-20},

number = {7},

doi = {10.1128/jcm.00128-20}

}

Publisher

American Society for Microbiology

Journal

Journal of Clinical Microbiology

scimago Q1

wos Q1

SJR

1.878

CiteScore

12.1

Impact factor

5.4

ISSN

00951137 (Print)

1098660X (Electronic)