Open Access
Macrophage-Derived Chemokine MDC/CCL22: An Ambiguous Finding in COVID-19
Тип публикации: Journal Article
Дата публикации: 2023-08-23
SCImago Q1
Tоп 10% SCImago
WOS Q1
БС1
SJR: 1.316
CiteScore: 10
Impact factor: 5.6
ISSN: 16616596, 14220067
PubMed ID:
37685890
Catalysis
Organic Chemistry
Inorganic Chemistry
Physical and Theoretical Chemistry
Computer Science Applications
Spectroscopy
Molecular Biology
General Medicine
Краткое описание
Macrophage-derived chemokine (MDC/CCL22) is a chemokine of the C-C subfamily. It is involved in T-cellular maturation and migration. Our previous research shows that plasma CCL22/MDC tends to show a statistically significant depletion of concentrations in acute patients and convalescents when compared to healthy donors. In the current work, we investigate existing views on MDC/CCL22 dynamics in association with various pathologies, including respiratory diseases and, specifically, COVID-19. Additionally, we present our explanations for the observed decrease in MDC/CCL22 concentrations in COVID-19. The first hypothesis we provide implies that viral products bind to MDC/CCL22 and block its activity. Another explanation for this phenomenon is based on dendritic cells population and the inhibition of their function.
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Метрики
17
Всего цитирований:
17
Цитирований c 2025:
12
(70.58%)
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MLA
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ГОСТ
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Korobova Z. R. et al. Macrophage-Derived Chemokine MDC/CCL22: An Ambiguous Finding in COVID-19 // International Journal of Molecular Sciences. 2023. Vol. 24. No. 17. p. 13083.
ГОСТ со всеми авторами (до 50)
Скопировать
Korobova Z. R., Arsentieva N. A., Totolian A. A. Macrophage-Derived Chemokine MDC/CCL22: An Ambiguous Finding in COVID-19 // International Journal of Molecular Sciences. 2023. Vol. 24. No. 17. p. 13083.
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RIS
Скопировать
TY - JOUR
DO - 10.3390/ijms241713083
UR - https://www.mdpi.com/1422-0067/24/17/13083
TI - Macrophage-Derived Chemokine MDC/CCL22: An Ambiguous Finding in COVID-19
T2 - International Journal of Molecular Sciences
AU - Korobova, Zoia R
AU - Arsentieva, Natalia A.
AU - Totolian, Areg A.
PY - 2023
DA - 2023/08/23
PB - MDPI
SP - 13083
IS - 17
VL - 24
PMID - 37685890
SN - 1661-6596
SN - 1422-0067
ER -
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BibTex (до 50 авторов)
Скопировать
@article{2023_Korobova,
author = {Zoia R Korobova and Natalia A. Arsentieva and Areg A. Totolian},
title = {Macrophage-Derived Chemokine MDC/CCL22: An Ambiguous Finding in COVID-19},
journal = {International Journal of Molecular Sciences},
year = {2023},
volume = {24},
publisher = {MDPI},
month = {aug},
url = {https://www.mdpi.com/1422-0067/24/17/13083},
number = {17},
pages = {13083},
doi = {10.3390/ijms241713083}
}
Цитировать
MLA
Скопировать
Korobova, Zoia R., et al. “Macrophage-Derived Chemokine MDC/CCL22: An Ambiguous Finding in COVID-19.” International Journal of Molecular Sciences, vol. 24, no. 17, Aug. 2023, p. 13083. https://www.mdpi.com/1422-0067/24/17/13083.
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