Open Access
Open access
Molecules, volume 25, issue 24, pages 5805

Modern Trends in the In Vitro Production and Use of Callus, Suspension Cells and Root Cultures of Medicinal Plants

Babich Olga 1
Sukhikh Stanislav 1, 2
Pungin Artem 1
Ivanova Svetlana 3, 4
Asyakina Lyudmila 2
Publication typeJournal Article
Publication date2020-12-09
Journal: Molecules
Quartile SCImago
Q1
Quartile WOS
Q2
Impact factor4.6
ISSN14203049
Organic Chemistry
Drug Discovery
Physical and Theoretical Chemistry
Pharmaceutical Science
Molecular Medicine
Analytical Chemistry
Chemistry (miscellaneous)
Abstract

This paper studies modern methods of producing and using callus, suspension cells and root cultures of medicinal plants in vitro. A new solution for natural product production is the use of an alternative source of renewable, environmentally friendly raw materials: callus, suspension and root cultures of higher plants in vitro. The possibility of using hairy root cultures as producers of various biologically active substances is studied. It is proven that the application of the genetic engineering achievements that combine in vitro tissue culture and molecular biology methods was groundbreaking in terms of the intensification of the extraction process of compounds significant for the medical industry. It is established that of all the callus processing methods, suspension and root cultures in vitro, the Agrobacterium method is the most widely used in practice. The use of agrobacteria has advantages over the biolistic method since it increases the proportion of stable transformation events, can deliver large DNA segments and does not require special ballistic devices. As a result of the research, the most effective strains of agrobacteria are identified.

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GOST Copy
Babich O. et al. Modern Trends in the In Vitro Production and Use of Callus, Suspension Cells and Root Cultures of Medicinal Plants // Molecules. 2020. Vol. 25. No. 24. p. 5805.
GOST all authors (up to 50) Copy
Babich O., Sukhikh S., Pungin A., Ivanova S., Asyakina L., Prosekov A. Modern Trends in the In Vitro Production and Use of Callus, Suspension Cells and Root Cultures of Medicinal Plants // Molecules. 2020. Vol. 25. No. 24. p. 5805.
RIS |
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RIS Copy
TY - JOUR
DO - 10.3390/molecules25245805
UR - https://doi.org/10.3390%2Fmolecules25245805
TI - Modern Trends in the In Vitro Production and Use of Callus, Suspension Cells and Root Cultures of Medicinal Plants
T2 - Molecules
AU - Sukhikh, Stanislav
AU - Asyakina, Lyudmila
AU - Babich, Olga
AU - Pungin, Artem
AU - Ivanova, Svetlana
AU - Prosekov, Alexander
PY - 2020
DA - 2020/12/09 00:00:00
PB - Multidisciplinary Digital Publishing Institute (MDPI)
SP - 5805
IS - 24
VL - 25
PMID - 33316965
SN - 1420-3049
ER -
BibTex |
Cite this
BibTex Copy
@article{2020_Babich,
author = {Stanislav Sukhikh and Lyudmila Asyakina and Olga Babich and Artem Pungin and Svetlana Ivanova and Alexander Prosekov},
title = {Modern Trends in the In Vitro Production and Use of Callus, Suspension Cells and Root Cultures of Medicinal Plants},
journal = {Molecules},
year = {2020},
volume = {25},
publisher = {Multidisciplinary Digital Publishing Institute (MDPI)},
month = {dec},
url = {https://doi.org/10.3390%2Fmolecules25245805},
number = {24},
pages = {5805},
doi = {10.3390/molecules25245805}
}
MLA
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MLA Copy
Babich, Olga, et al. “Modern Trends in the In Vitro Production and Use of Callus, Suspension Cells and Root Cultures of Medicinal Plants.” Molecules, vol. 25, no. 24, Dec. 2020, p. 5805. https://doi.org/10.3390%2Fmolecules25245805.
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