Development of modern methods for the synthesis of heterocyclic compounds with various substituents, search and synthesis of antitumor drugs.

Development of new methods for the synthesis and structural modification of various nitrogen-containing heterocyclic compounds of a number of oxadiazole, imidazotriazine and glycoluryl, as well as the study of their properties to yield pharmacologically active compounds or functional organic materials.

Synthesis and chemical properties of new polyser- and sulfur-nitrogenous heterocyclic compounds, which can be aromatic and antiaromatic, as well as systems with extended conjugation.

The laboratory conducts research in the field of development, synthesis and study of a new class of therapeutic agents – antibody drug conjugates (ADC), which perform an important function – the delivery of a powerful cytotoxic agent to tumor cells with minimal damage to healthy tissues. The laboratory develops antibody-drug conjugates (ADCs) for targeted delivery of chemotherapy drugs in the treatment of oncological diseases. Linkers binding monoclonal antibodies to a chemical agent or natural chloride are being developed. The study of biological and chemical properties of new pharmaceutical substances in the laboratory.