Die Pharmazie

Govi Verlag Pharmazeutischer Verlag GmbH

ISSN: 00317144, 3053691X

Публикации журнала в Cobalt

Вы ученый?

Создайте профиль, чтобы получать персональные рекомендации коллег, конференций и новых статей.

Войти с ORCID

SCImago

WOS

БС

БС3

Impact factor

SJR

0.231

CiteScore

Предметные категории

Pharmaceutical Science

Предметные области

Pharmacology, Toxicology and Pharmaceutics

Годы выпуска

1947-2023

Варианты названий

Die Pharmazie

Страница журнала в БС

Сайт журнала

за всё время с 2021

Публикаций

828

Цитирований

2 017

Индекс Хирша

Публикаций

239

Цитирований

1 739

Топ-3 цитирующих журналов

Frontiers in Pharmacology (150 цитирований)

Frontiers in Oncology (51 цитирование)

Pharmaceutics (43 цитирования)

Топ-3 учёных по количеству статей

3 публикации в журнале

Лофцсон Тхорстейнн

301 публикация, 21 808 цитирований, 4 рецензии

Индекс Хирша 65

Исландский университет

2 публикации в журнале

Нисида Шохей

22 публикации, 231 цитирование

Индекс Хирша 8

1 публикация в журнале

Укротительница Ильбасмы Сибел

44 публикации, 776 цитирований, 19 рецензий

Индекс Хирша 18

Университет Гази

Ближневосточный технический университет

Наиболее цитируемые за 5 лет

Название публикации

Топ-100

Цитирующие журналы

	20 40 60 80 100 120 140 160
Frontiers in Pharmacology	Frontiers in Pharmacology, 150, 7.44% Frontiers in Pharmacology 150 цитирований, 7.44%
Frontiers in Oncology	Frontiers in Oncology, 51, 2.53% Frontiers in Oncology 51 цитирование, 2.53%
Pharmaceutics	Pharmaceutics, 43, 2.13% Pharmaceutics 43 цитирования, 2.13%
Frontiers in Immunology	Frontiers in Immunology, 40, 1.98% Frontiers in Immunology 40 цитирований, 1.98%
International Journal of Molecular Sciences	International Journal of Molecular Sciences, 39, 1.93% International Journal of Molecular Sciences 39 цитирований, 1.93%
Scientific Reports	Scientific Reports, 27, 1.34% Scientific Reports 27 цитирований, 1.34%
Molecules	Molecules, 25, 1.24% Molecules 25 цитирований, 1.24%
Frontiers in Cell and Developmental Biology	Frontiers in Cell and Developmental Biology, 24, 1.19% Frontiers in Cell and Developmental Biology 24 цитирования, 1.19%
International Journal of Nanomedicine	International Journal of Nanomedicine, 23, 1.14% International Journal of Nanomedicine 23 цитирования, 1.14%
Cancers	Cancers, 22, 1.09% Cancers 22 цитирования, 1.09%
BioMed Research International	BioMed Research International, 20, 0.99% BioMed Research International 20 цитирований, 0.99%
Oxidative Medicine and Cellular Longevity	Oxidative Medicine and Cellular Longevity, 20, 0.99% Oxidative Medicine and Cellular Longevity 20 цитирований, 0.99%
Experimental and Therapeutic Medicine	Experimental and Therapeutic Medicine, 20, 0.99% Experimental and Therapeutic Medicine 20 цитирований, 0.99%
Aging	Aging, 19, 0.94% Aging 19 цитирований, 0.94%
Frontiers in Endocrinology	Frontiers in Endocrinology, 19, 0.94% Frontiers in Endocrinology 19 цитирований, 0.94%
bioRxiv	bioRxiv, 19, 0.94% bioRxiv 19 цитирований, 0.94%
Frontiers in Genetics	Frontiers in Genetics, 18, 0.89% Frontiers in Genetics 18 цитирований, 0.89%
Evidence-based Complementary and Alternative Medicine	Evidence-based Complementary and Alternative Medicine, 18, 0.89% Evidence-based Complementary and Alternative Medicine 18 цитирований, 0.89%
Phytotherapy Research	Phytotherapy Research, 14, 0.69% Phytotherapy Research 14 цитирований, 0.69%
Journal of Agricultural and Food Chemistry	Journal of Agricultural and Food Chemistry, 14, 0.69% Journal of Agricultural and Food Chemistry 14 цитирований, 0.69%
Frontiers in Medicine	Frontiers in Medicine, 13, 0.64% Frontiers in Medicine 13 цитирований, 0.64%
ACS Omega	ACS Omega, 13, 0.64% ACS Omega 13 цитирований, 0.64%
Cureus	Cureus, 13, 0.64% Cureus 13 цитирований, 0.64%
OncoTargets and Therapy	OncoTargets and Therapy, 12, 0.59% OncoTargets and Therapy 12 цитирований, 0.59%
Frontiers in Bioengineering and Biotechnology	Frontiers in Bioengineering and Biotechnology, 12, 0.59% Frontiers in Bioengineering and Biotechnology 12 цитирований, 0.59%
Cancer Management and Research	Cancer Management and Research, 12, 0.59% Cancer Management and Research 12 цитирований, 0.59%
Drug Design, Development and Therapy	Drug Design, Development and Therapy, 11, 0.55% Drug Design, Development and Therapy 11 цитирований, 0.55%
Pharmaceuticals	Pharmaceuticals, 10, 0.5% Pharmaceuticals 10 цитирований, 0.5%
Nutrients	Nutrients, 10, 0.5% Nutrients 10 цитирований, 0.5%
Naunyn-Schmiedeberg's Archives of Pharmacology	Naunyn-Schmiedeberg's Archives of Pharmacology, 10, 0.5% Naunyn-Schmiedeberg's Archives of Pharmacology 10 цитирований, 0.5%
AAPS PharmSciTech	AAPS PharmSciTech, 10, 0.5% AAPS PharmSciTech 10 цитирований, 0.5%
Molecular Pharmaceutics	Molecular Pharmaceutics, 10, 0.5% Molecular Pharmaceutics 10 цитирований, 0.5%
Biomedical Chromatography	Biomedical Chromatography, 9, 0.45% Biomedical Chromatography 9 цитирований, 0.45%
Frontiers in Neurology	Frontiers in Neurology, 9, 0.45% Frontiers in Neurology 9 цитирований, 0.45%
Frontiers in Nutrition	Frontiers in Nutrition, 9, 0.45% Frontiers in Nutrition 9 цитирований, 0.45%
European Journal of Hospital Pharmacy	European Journal of Hospital Pharmacy, 9, 0.45% European Journal of Hospital Pharmacy 9 цитирований, 0.45%
Cells	Cells, 9, 0.45% Cells 9 цитирований, 0.45%
PeerJ	PeerJ, 8, 0.4% PeerJ 8 цитирований, 0.4%
Frontiers in Cardiovascular Medicine	Frontiers in Cardiovascular Medicine, 8, 0.4% Frontiers in Cardiovascular Medicine 8 цитирований, 0.4%
Frontiers in Veterinary Science	Frontiers in Veterinary Science, 8, 0.4% Frontiers in Veterinary Science 8 цитирований, 0.4%
Current Medicinal Chemistry	Current Medicinal Chemistry, 8, 0.4% Current Medicinal Chemistry 8 цитирований, 0.4%
Journal of Inflammation Research	Journal of Inflammation Research, 8, 0.4% Journal of Inflammation Research 8 цитирований, 0.4%
Frontiers in Microbiology	Frontiers in Microbiology, 8, 0.4% Frontiers in Microbiology 8 цитирований, 0.4%
Journal of Immunology Research	Journal of Immunology Research, 7, 0.35% Journal of Immunology Research 7 цитирований, 0.35%
Critical Reviews in Food Science and Nutrition	Critical Reviews in Food Science and Nutrition, 7, 0.35% Critical Reviews in Food Science and Nutrition 7 цитирований, 0.35%
Frontiers in Chemistry	Frontiers in Chemistry, 7, 0.35% Frontiers in Chemistry 7 цитирований, 0.35%
World Journal of Gastrointestinal Oncology	World Journal of Gastrointestinal Oncology, 7, 0.35% World Journal of Gastrointestinal Oncology 7 цитирований, 0.35%
Frontiers in Cellular and Infection Microbiology	Frontiers in Cellular and Infection Microbiology, 7, 0.35% Frontiers in Cellular and Infection Microbiology 7 цитирований, 0.35%
Journal of Pharmaceutical Innovation	Journal of Pharmaceutical Innovation, 7, 0.35% Journal of Pharmaceutical Innovation 7 цитирований, 0.35%
Journal of Clinical Medicine	Journal of Clinical Medicine, 7, 0.35% Journal of Clinical Medicine 7 цитирований, 0.35%
Molecular Biology Reports	Molecular Biology Reports, 6, 0.3% Molecular Biology Reports 6 цитирований, 0.3%
Frontiers in Molecular Biosciences	Frontiers in Molecular Biosciences, 6, 0.3% Frontiers in Molecular Biosciences 6 цитирований, 0.3%
Journal of Medicinal Chemistry	Journal of Medicinal Chemistry, 6, 0.3% Journal of Medicinal Chemistry 6 цитирований, 0.3%
British Journal of Clinical Pharmacology	British Journal of Clinical Pharmacology, 6, 0.3% British Journal of Clinical Pharmacology 6 цитирований, 0.3%
Journal of Food Biochemistry	Journal of Food Biochemistry, 6, 0.3% Journal of Food Biochemistry 6 цитирований, 0.3%
Critical Reviews in Analytical Chemistry	Critical Reviews in Analytical Chemistry, 6, 0.3% Critical Reviews in Analytical Chemistry 6 цитирований, 0.3%
Molecular and Cellular Biochemistry	Molecular and Cellular Biochemistry, 6, 0.3% Molecular and Cellular Biochemistry 6 цитирований, 0.3%
Journal of Cellular and Molecular Medicine	Journal of Cellular and Molecular Medicine, 6, 0.3% Journal of Cellular and Molecular Medicine 6 цитирований, 0.3%
Frontiers in Physiology	Frontiers in Physiology, 6, 0.3% Frontiers in Physiology 6 цитирований, 0.3%
Computational and Mathematical Methods in Medicine	Computational and Mathematical Methods in Medicine, 6, 0.3% Computational and Mathematical Methods in Medicine 6 цитирований, 0.3%
ACS Applied Bio Materials	ACS Applied Bio Materials, 6, 0.3% ACS Applied Bio Materials 6 цитирований, 0.3%
Molecular Neurobiology	Molecular Neurobiology, 6, 0.3% Molecular Neurobiology 6 цитирований, 0.3%
Biomedicines	Biomedicines, 6, 0.3% Biomedicines 6 цитирований, 0.3%
ACS Applied Nano Materials	ACS Applied Nano Materials, 5, 0.25% ACS Applied Nano Materials 5 цитирований, 0.25%
Molecular and Clinical Oncology	Molecular and Clinical Oncology, 5, 0.25% Molecular and Clinical Oncology 5 цитирований, 0.25%
Journal of Healthcare Engineering	Journal of Healthcare Engineering, 5, 0.25% Journal of Healthcare Engineering 5 цитирований, 0.25%
Archives of Pharmacal Research	Archives of Pharmacal Research, 5, 0.25% Archives of Pharmacal Research 5 цитирований, 0.25%
European Journal of Clinical Pharmacology	European Journal of Clinical Pharmacology, 5, 0.25% European Journal of Clinical Pharmacology 5 цитирований, 0.25%
World Chinese Journal of Digestology	World Chinese Journal of Digestology, 5, 0.25% World Chinese Journal of Digestology 5 цитирований, 0.25%
Antioxidants	Antioxidants, 5, 0.25% Antioxidants 5 цитирований, 0.25%
World Journal of Gastroenterology	World Journal of Gastroenterology, 5, 0.25% World Journal of Gastroenterology 5 цитирований, 0.25%
International Journal of General Medicine	International Journal of General Medicine, 5, 0.25% International Journal of General Medicine 5 цитирований, 0.25%
International Journal of Biological Macromolecules	International Journal of Biological Macromolecules, 5, 0.25% International Journal of Biological Macromolecules 5 цитирований, 0.25%
Biochemical Genetics	Biochemical Genetics, 4, 0.2% Biochemical Genetics 4 цитирования, 0.2%
Food Science and Human Wellness	Food Science and Human Wellness, 4, 0.2% Food Science and Human Wellness 4 цитирования, 0.2%
Frontiers in Pediatrics	Frontiers in Pediatrics, 4, 0.2% Frontiers in Pediatrics 4 цитирования, 0.2%
Journal of Personalized Medicine	Journal of Personalized Medicine, 4, 0.2% Journal of Personalized Medicine 4 цитирования, 0.2%
Journal of Molecular Neuroscience	Journal of Molecular Neuroscience, 4, 0.2% Journal of Molecular Neuroscience 4 цитирования, 0.2%
BMJ Open	BMJ Open, 4, 0.2% BMJ Open 4 цитирования, 0.2%
Frontiers in Psychiatry	Frontiers in Psychiatry, 4, 0.2% Frontiers in Psychiatry 4 цитирования, 0.2%
Pharmacogenomics and Personalized Medicine	Pharmacogenomics and Personalized Medicine, 4, 0.2% Pharmacogenomics and Personalized Medicine 4 цитирования, 0.2%
Pharmaceutical Development and Technology	Pharmaceutical Development and Technology, 4, 0.2% Pharmaceutical Development and Technology 4 цитирования, 0.2%
Drug Delivery and Translational Research	Drug Delivery and Translational Research, 4, 0.2% Drug Delivery and Translational Research 4 цитирования, 0.2%
Neurochemical Research	Neurochemical Research, 4, 0.2% Neurochemical Research 4 цитирования, 0.2%
Journal of Oncology	Journal of Oncology, 4, 0.2% Journal of Oncology 4 цитирования, 0.2%
Current Pharmaceutical Design	Current Pharmaceutical Design, 4, 0.2% Current Pharmaceutical Design 4 цитирования, 0.2%
Crystal Growth and Design	Crystal Growth and Design, 4, 0.2% Crystal Growth and Design 4 цитирования, 0.2%
Journal of Ethnopharmacology	Journal of Ethnopharmacology, 4, 0.2% Journal of Ethnopharmacology 4 цитирования, 0.2%
Biomolecules	Biomolecules, 4, 0.2% Biomolecules 4 цитирования, 0.2%
Biochemistry and Cell Biology	Biochemistry and Cell Biology, 4, 0.2% Biochemistry and Cell Biology 4 цитирования, 0.2%
Frontiers in Neuroscience	Frontiers in Neuroscience, 4, 0.2% Frontiers in Neuroscience 4 цитирования, 0.2%
Plants	Plants, 4, 0.2% Plants 4 цитирования, 0.2%
Advances in Experimental Medicine and Biology	Advances in Experimental Medicine and Biology, 4, 0.2% Advances in Experimental Medicine and Biology 4 цитирования, 0.2%
British Journal of Pharmacology	British Journal of Pharmacology, 4, 0.2% British Journal of Pharmacology 4 цитирования, 0.2%
ACS Biomaterials Science and Engineering	ACS Biomaterials Science and Engineering, 4, 0.2% ACS Biomaterials Science and Engineering 4 цитирования, 0.2%
Clinical and Translational Oncology	Clinical and Translational Oncology, 4, 0.2% Clinical and Translational Oncology 4 цитирования, 0.2%
Medicine (United States)	Medicine (United States), 4, 0.2% Medicine (United States) 4 цитирования, 0.2%
3 Biotech	3 Biotech, 4, 0.2% 3 Biotech 4 цитирования, 0.2%
Stem Cells International	Stem Cells International, 4, 0.2% Stem Cells International 4 цитирования, 0.2%
Toxicological Research	Toxicological Research, 4, 0.2% Toxicological Research 4 цитирования, 0.2%

	20 40 60 80 100 120 140 160

Цитирующие издатели

	50 100 150 200 250 300 350 400 450
Frontiers Media S.A.	Frontiers Media S.A., 434, 21.52% Frontiers Media S.A. 434 цитирования, 21.52%
Springer Nature	Springer Nature, 361, 17.9% Springer Nature 361 цитирование, 17.9%
MDPI	MDPI, 241, 11.95% MDPI 241 цитирование, 11.95%
Taylor & Francis	Taylor & Francis, 162, 8.03% Taylor & Francis 162 цитирования, 8.03%
Wiley	Wiley, 137, 6.79% Wiley 137 цитирований, 6.79%
Hindawi Limited	Hindawi Limited, 108, 5.35% Hindawi Limited 108 цитирований, 5.35%
Elsevier	Elsevier, 91, 4.51% Elsevier 91 цитирование, 4.51%
American Chemical Society (ACS)	American Chemical Society (ACS), 86, 4.26% American Chemical Society (ACS) 86 цитирований, 4.26%
Spandidos Publications	Spandidos Publications, 32, 1.59% Spandidos Publications 32 цитирования, 1.59%
Bentham Science Publishers Ltd.	Bentham Science Publishers Ltd., 30, 1.49% Bentham Science Publishers Ltd. 30 цитирований, 1.49%
Baishideng Publishing Group	Baishideng Publishing Group, 28, 1.39% Baishideng Publishing Group 28 цитирований, 1.39%
	, 27, 1.34% 27 цитирований, 1.34%
BMJ	BMJ, 27, 1.34% BMJ 27 цитирований, 1.34%
Impact Journals	Impact Journals, 20, 0.99% Impact Journals 20 цитирований, 0.99%
openRxiv	openRxiv, 20, 0.99% openRxiv 20 цитирований, 0.99%
SAGE	SAGE, 15, 0.74% SAGE 15 цитирований, 0.74%
Ovid Technologies (Wolters Kluwer Health)	Ovid Technologies (Wolters Kluwer Health), 13, 0.64% Ovid Technologies (Wolters Kluwer Health) 13 цитирований, 0.64%
Oxford University Press	Oxford University Press, 11, 0.55% Oxford University Press 11 цитирований, 0.55%
Pleiades Publishing	Pleiades Publishing, 10, 0.5% Pleiades Publishing 10 цитирований, 0.5%
Cold Spring Harbor Laboratory	Cold Spring Harbor Laboratory, 9, 0.45% Cold Spring Harbor Laboratory 9 цитирований, 0.45%
S. Karger AG	S. Karger AG, 9, 0.45% S. Karger AG 9 цитирований, 0.45%
Mary Ann Liebert	Mary Ann Liebert, 8, 0.4% Mary Ann Liebert 8 цитирований, 0.4%
PeerJ	PeerJ, 8, 0.4% PeerJ 8 цитирований, 0.4%
Georg Thieme Verlag KG	Georg Thieme Verlag KG, 7, 0.35% Georg Thieme Verlag KG 7 цитирований, 0.35%
Canadian Science Publishing	Canadian Science Publishing, 7, 0.35% Canadian Science Publishing 7 цитирований, 0.35%
American Physiological Society	American Physiological Society, 6, 0.3% American Physiological Society 6 цитирований, 0.3%
IOP Publishing	IOP Publishing, 5, 0.25% IOP Publishing 5 цитирований, 0.25%
JMIR Publications	JMIR Publications, 5, 0.25% JMIR Publications 5 цитирований, 0.25%
Royal Society of Chemistry (RSC)	Royal Society of Chemistry (RSC), 4, 0.2% Royal Society of Chemistry (RSC) 4 цитирования, 0.2%
American Society for Microbiology	American Society for Microbiology, 4, 0.2% American Society for Microbiology 4 цитирования, 0.2%
Pensoft Publishers	Pensoft Publishers, 4, 0.2% Pensoft Publishers 4 цитирования, 0.2%
Tsinghua University Press	Tsinghua University Press, 4, 0.2% Tsinghua University Press 4 цитирования, 0.2%
Science Alert	Science Alert, 4, 0.2% Science Alert 4 цитирования, 0.2%
F1000 Research	F1000 Research, 4, 0.2% F1000 Research 4 цитирования, 0.2%
Portland Press	Portland Press, 3, 0.15% Portland Press 3 цитирования, 0.15%
Korean Association of Medical Journal Editors	Korean Association of Medical Journal Editors, 3, 0.15% Korean Association of Medical Journal Editors 3 цитирования, 0.15%
OAE Publishing Inc.	OAE Publishing Inc., 3, 0.15% OAE Publishing Inc. 3 цитирования, 0.15%
Pharmaceutical Society of Korea	Pharmaceutical Society of Korea, 3, 0.15% Pharmaceutical Society of Korea 3 цитирования, 0.15%
Public Library of Science (PLoS)	Public Library of Science (PLoS), 2, 0.1% Public Library of Science (PLoS) 2 цитирования, 0.1%
The Korean Pain Society	The Korean Pain Society, 2, 0.1% The Korean Pain Society 2 цитирования, 0.1%
	, 2, 0.1% 2 цитирования, 0.1%
Moffitt Cancer Center	Moffitt Cancer Center, 2, 0.1% Moffitt Cancer Center 2 цитирования, 0.1%
eLife Sciences Publications	eLife Sciences Publications, 2, 0.1% eLife Sciences Publications 2 цитирования, 0.1%
Brieflands	Brieflands, 2, 0.1% Brieflands 2 цитирования, 0.1%
Research Square Platform LLC	Research Square Platform LLC, 2, 0.1% Research Square Platform LLC 2 цитирования, 0.1%
Emerald	Emerald, 1, 0.05% Emerald 1 цитирование, 0.05%
American Society for Horticultural Science	American Society for Horticultural Science, 1, 0.05% American Society for Horticultural Science 1 цитирование, 0.05%
Microbiology Society	Microbiology Society, 1, 0.05% Microbiology Society 1 цитирование, 0.05%
Zhejiang University Press	Zhejiang University Press, 1, 0.05% Zhejiang University Press 1 цитирование, 0.05%
AME Publishing Company	AME Publishing Company, 1, 0.05% AME Publishing Company 1 цитирование, 0.05%
Editorial Office of Gut and Liver	Editorial Office of Gut and Liver, 1, 0.05% Editorial Office of Gut and Liver 1 цитирование, 0.05%
Korean Society for Microbiolog and Biotechnology	Korean Society for Microbiolog and Biotechnology, 1, 0.05% Korean Society for Microbiolog and Biotechnology 1 цитирование, 0.05%
American Medical Association (AMA)	American Medical Association (AMA), 1, 0.05% American Medical Association (AMA) 1 цитирование, 0.05%
Canadian Pharmacists Association	Canadian Pharmacists Association, 1, 0.05% Canadian Pharmacists Association 1 цитирование, 0.05%
Korean Society of Plant Biotechnology	Korean Society of Plant Biotechnology, 1, 0.05% Korean Society of Plant Biotechnology 1 цитирование, 0.05%
Federation of American Societies for Experimental Biology (FASEB)	Federation of American Societies for Experimental Biology (FASEB), 1, 0.05% Federation of American Societies for Experimental Biology (FASEB) 1 цитирование, 0.05%
American Veterinary Medical Association	American Veterinary Medical Association, 1, 0.05% American Veterinary Medical Association 1 цитирование, 0.05%
The Korean Society for Applied Biological Chemistry	The Korean Society for Applied Biological Chemistry, 1, 0.05% The Korean Society for Applied Biological Chemistry 1 цитирование, 0.05%
	, 1, 0.05% 1 цитирование, 0.05%
AOAC International	AOAC International, 1, 0.05% AOAC International 1 цитирование, 0.05%
Eui-Hak Publishing and Printing Co.	Eui-Hak Publishing and Printing Co., 1, 0.05% Eui-Hak Publishing and Printing Co. 1 цитирование, 0.05%
Beilstein-Institut	Beilstein-Institut, 1, 0.05% Beilstein-Institut 1 цитирование, 0.05%
Institute of Electrical and Electronics Engineers (IEEE)	Institute of Electrical and Electronics Engineers (IEEE), 1, 0.05% Institute of Electrical and Electronics Engineers (IEEE) 1 цитирование, 0.05%
The Russian Academy of Sciences	The Russian Academy of Sciences, 1, 0.05% The Russian Academy of Sciences 1 цитирование, 0.05%
Media Sphere Publishing House	Media Sphere Publishing House, 1, 0.05% Media Sphere Publishing House 1 цитирование, 0.05%
IGI Global	IGI Global, 1, 0.05% IGI Global 1 цитирование, 0.05%
Maximum Academic Press	Maximum Academic Press, 1, 0.05% Maximum Academic Press 1 цитирование, 0.05%
Scientific Scholar	Scientific Scholar, 1, 0.05% Scientific Scholar 1 цитирование, 0.05%
Society of Korean Medicine for Obesity Research	Society of Korean Medicine for Obesity Research, 1, 0.05% Society of Korean Medicine for Obesity Research 1 цитирование, 0.05%
The Korean College of Clinical Pharmacy	The Korean College of Clinical Pharmacy, 1, 0.05% The Korean College of Clinical Pharmacy 1 цитирование, 0.05%

	50 100 150 200 250 300 350 400 450