Open Access

Nutrients

, volume 12 , issue 3 , pages 872

Chemical Constituents and Pharmacological Activities of Garlic (Allium sativum L.): A Review

Gaber El-Saber Batiha ^{1, 2}

Amany Magdy Beshbishy ¹

Lamiaa G Wasef ²

Yaser H A Elewa ^{3, 4}

Saad A. Alkahtani ⁵

Mohamed E. Abd El-Hack ⁶

Khaled A El-Tarabily ⁷

Yasmina M. Abd-Elhakim ⁸

Hari Prasad Devkota ⁹

Hide authors affiliations Show authors affiliations: 9 affiliations

National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Nishi 2-13, Inada-cho, Obihiro, Hokkaido 080-8555, Japan |

Department of Pharmacology and Therapeutics, Faculty of Veterinary Medicine, Damanhour University, Damanhour 22511, Albeheira, Egypt |

Department of Histology and Cytology, Faculty of Veterinary Medicine, Zagazig University, Zagazig 44511, Egypt |

⁴

Laboratory of Anatomy, Department of Biomedical Sciences, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Hokkaido 060-0818, Japan |

⁵

King Abdulaziz City for Science and Technology, P.O. Box 6086, Riyadh 11442, Saudi Arabia |

⁶

Department of Poultry, Faculty of Agriculture, Zagazig University, Zagazig 44511, Egypt |

⁷

Department of Animal Husbandry and Animal Wealth Development, Faculty of Veterinary Medicine, Alexandria University, Edfina 22578, Egypt |

⁸

Department of Forensic Medicine and Toxicology, Faculty of Veterinary Medicine, Zagazig University, Zagazig 44511, Egypt |

⁹

Graduate School of Pharmaceutical Sciences, Kumamoto University, 5-1 Oe-Honmachi, Chuo-ku, Kumamoto City, Kumamoto, 862-0973, Japan |

Publication type: Journal Article

Publication date: 2020-03-24

MDPI

Nutrients

scimago Q1

wos Q1

SJR: 1.473

CiteScore: 9.1

Impact factor: 5.0

ISSN: 20726643

DOI: 10.3390/nu12030872

Copy DOI

PubMed ID: 32213941

Food Science

Nutrition and Dietetics

Abstract

Medicinal plants have been used from ancient times for human healthcare as in the form of traditional medicines, spices, and other food components. Garlic (Allium sativum L.) is an aromatic herbaceous plant that is consumed worldwide as food and traditional remedy for various diseases. It has been reported to possess several biological properties including anticarcinogenic, antioxidant, antidiabetic, renoprotective, anti-atherosclerotic, antibacterial, antifungal, and antihypertensive activities in traditional medicines. A. sativum is rich in several sulfur-containing phytoconstituents such as alliin, allicin, ajoenes, vinyldithiins, and flavonoids such as quercetin. Extracts and isolated compounds of A. sativum have been evaluated for various biological activities including antibacterial, antiviral, antifungal, antiprotozoal, antioxidant, anti-inflammatory, and anticancer activities among others. This review examines the phytochemical composition, pharmacokinetics, and pharmacological activities of A. sativum extracts as well as its main active constituent, allicin.

Found

2 citations

El-Saadony Mohamed

🥼 🤝

DSc in Agricultural sciences, professor, professor of the Egyptian Academy of Scientific Research and Technology

228 publications, 10 804 citations, 342 reviews

2 citations

Revtovich Svetlana

🥼

48 publications, 478 citations

h-index: 14

Engelhardt Institute of Molecular Biology of the Russian Academy of Sciences

Research interests

Drug design

Structural Biology

1 citation

BOUSLAMA Lamjed

43 publications, 644 citations, 3 reviews

h-index: 15

Tunis El Manar University

Center of Biotechnogy of Borj Cédria

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Batiha G. E. et al. Chemical Constituents and Pharmacological Activities of Garlic (Allium sativum L.): A Review // Nutrients. 2020. Vol. 12. No. 3. p. 872.

GOST all authors (up to 50) Copy

Batiha G. E., Magdy Beshbishy A., G Wasef L., Elewa Y. H. A., Alkahtani S. A., Abd El-Hack M. E., El-Tarabily K. A., Abd-Elhakim Y. M., Devkota H. P. Chemical Constituents and Pharmacological Activities of Garlic (Allium sativum L.): A Review // Nutrients. 2020. Vol. 12. No. 3. p. 872.

RIS |

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RIS Copy

TY - JOUR

DO - 10.3390/nu12030872

UR - https://doi.org/10.3390/nu12030872

TI - Chemical Constituents and Pharmacological Activities of Garlic (Allium sativum L.): A Review

T2 - Nutrients

AU - Batiha, Gaber El-Saber

AU - Magdy Beshbishy, Amany

AU - G Wasef, Lamiaa

AU - Elewa, Yaser H A

AU - Alkahtani, Saad A.

AU - Abd El-Hack, Mohamed E.

AU - El-Tarabily, Khaled A

AU - Abd-Elhakim, Yasmina M.

AU - Devkota, Hari Prasad

PY - 2020

DA - 2020/03/24

PB - MDPI

SP - 872

IS - 3

VL - 12

PMID - 32213941

SN - 2072-6643

ER -

BibTex |

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BibTex (up to 50 authors) Copy

@article{2020_Batiha,

author = {Gaber El-Saber Batiha and Amany Magdy Beshbishy and Lamiaa G Wasef and Yaser H A Elewa and Saad A. Alkahtani and Mohamed E. Abd El-Hack and Khaled A El-Tarabily and Yasmina M. Abd-Elhakim and Hari Prasad Devkota},

title = {Chemical Constituents and Pharmacological Activities of Garlic (Allium sativum L.): A Review},

journal = {Nutrients},

year = {2020},

volume = {12},

publisher = {MDPI},

month = {mar},

url = {https://doi.org/10.3390/nu12030872},

number = {3},

pages = {872},

doi = {10.3390/nu12030872}

}

MLA

Cite this

MLA Copy

Batiha, Gaber El-Saber, et al. “Chemical Constituents and Pharmacological Activities of Garlic (Allium sativum L.): A Review.” Nutrients, vol. 12, no. 3, Mar. 2020, p. 872. https://doi.org/10.3390/nu12030872.

Publisher

MDPI

Journal

Nutrients

scimago Q1

wos Q1

SJR

1.473

CiteScore

9.1

Impact factor

5.0

ISSN

20726643 (Print, Electronic)