Open Access

Biomolecules

, том 12 , издание 3 , страницы 472

Glucose Oxidase, an Enzyme “Ferrari”: Its Structure, Function, Production and Properties in the Light of Various Industrial and Biotechnological Applications

JACOB H. BAUER ¹

Monika Zámocká ¹

Juraj Majtan ^{1, 2}

Vladena Bauerova-Hlinkova ¹

Скрыть аффилиации авторов Показать аффилиации авторов: 2 аффилиации

Institute of Molecular Biology, Slovak Academy of Sciences, 845 51 Bratislava, Slovakia |

Department of Microbiology, Faculty of Medicine, Slovak Medical University, Limbová 12, 833 03 Bratislava, Slovakia |

Тип публикации: Journal Article

Дата публикации: 2022-03-19

MDPI

Biomolecules

scimago Q1

wos Q1

БС1

SJR: 1.333

CiteScore: 9.2

Impact factor: 4.8

ISSN: 2218273X

DOI: 10.3390/biom12030472

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PubMed ID: 35327664

Biochemistry

Molecular Biology

Краткое описание

Glucose oxidase (GOx) is an important oxidoreductase enzyme with many important roles in biological processes. It is considered an “ideal enzyme” and is often called an oxidase “Ferrari” because of its fast mechanism of action, high stability and specificity. Glucose oxidase catalyzes the oxidation of β-d-glucose to d-glucono-δ-lactone and hydrogen peroxide in the presence of molecular oxygen. d-glucono-δ-lactone is sequentially hydrolyzed by lactonase to d-gluconic acid, and the resulting hydrogen peroxide is hydrolyzed by catalase to oxygen and water. GOx is presently known to be produced only by fungi and insects. The current main industrial producers of glucose oxidase are Aspergillus and Penicillium. An important property of GOx is its antimicrobial effect against various pathogens and its use in many industrial and medical areas. The aim of this review is to summarize the structure, function, production strains and biophysical and biochemical properties of GOx in light of its various industrial, biotechnological and medical applications.

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Кузнецова Ирен

д.ф.-м.н., доц.

258 публикаций, 2 543 цитирования, 63 рецензии

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Институт радиотехники и электроники имени В.А. Котельникова РАН

Области научных интересов

Акустика

Пьезоэлектрики

Сенсоры

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Гайнанова Гульнара

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74 публикации, 1 073 цитирования, 1 рецензия

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Институт органической и физической химии им. А.Е. Арбузова КазНЦ РАН

Области научных интересов

Коллоидная химия

Поверхностно-активные вещества

Системы доставки лекарственных веществ

Супрамолекулярная химия

Физическая химия

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Институт органической и физической химии им. А.Е. Арбузова КазНЦ РАН

Области научных интересов

Коллоидная химия

Поверхностно-активные вещества

Системы доставки лекарственных веществ

Физическая химия

1 цитирование

Захарова Люция

д.х.н., проф.

394 публикации, 6 176 цитирований

Индекс Хирша: 37

Институт органической и физической химии им. А.Е. Арбузова КазНЦ РАН

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BAUER J. H. et al. Glucose Oxidase, an Enzyme “Ferrari”: Its Structure, Function, Production and Properties in the Light of Various Industrial and Biotechnological Applications // Biomolecules. 2022. Vol. 12. No. 3. p. 472.

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BAUER J. H., Zámocká M., Majtan J., Bauerova-Hlinkova V. Glucose Oxidase, an Enzyme “Ferrari”: Its Structure, Function, Production and Properties in the Light of Various Industrial and Biotechnological Applications // Biomolecules. 2022. Vol. 12. No. 3. p. 472.

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TY - JOUR

DO - 10.3390/biom12030472

UR - https://doi.org/10.3390/biom12030472

TI - Glucose Oxidase, an Enzyme “Ferrari”: Its Structure, Function, Production and Properties in the Light of Various Industrial and Biotechnological Applications

T2 - Biomolecules

AU - BAUER, JACOB H.

AU - Zámocká, Monika

AU - Majtan, Juraj

AU - Bauerova-Hlinkova, Vladena

PY - 2022

DA - 2022/03/19

PB - MDPI

SP - 472

IS - 3

VL - 12

PMID - 35327664

SN - 2218-273X

ER -

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@article{2022_BAUER,

author = {JACOB H. BAUER and Monika Zámocká and Juraj Majtan and Vladena Bauerova-Hlinkova},

title = {Glucose Oxidase, an Enzyme “Ferrari”: Its Structure, Function, Production and Properties in the Light of Various Industrial and Biotechnological Applications},

journal = {Biomolecules},

year = {2022},

volume = {12},

publisher = {MDPI},

month = {mar},

url = {https://doi.org/10.3390/biom12030472},

number = {3},

pages = {472},

doi = {10.3390/biom12030472}

}

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BAUER, JACOB H., et al. “Glucose Oxidase, an Enzyme “Ferrari”: Its Structure, Function, Production and Properties in the Light of Various Industrial and Biotechnological Applications.” Biomolecules, vol. 12, no. 3, Mar. 2022, p. 472. https://doi.org/10.3390/biom12030472.

Издатель

MDPI

Журнал

Biomolecules

scimago Q1

wos Q1

БС1

SJR

1.333

CiteScore

9.2

Impact factor

4.8

ISSN

2218273X (Electronic)