Ecdysteroids: isolation, chemical transformations, and biological activity
Publication type: Journal Article
Publication date: 2022-01-04
scimago Q1
wos Q1
SJR: 1.431
CiteScore: 16.3
Impact factor: 7.6
ISSN: 15687767, 1572980X
Plant Science
Biotechnology
Abstract
Ecdysteroids are polyhydroxylated sterols, and are widespread in the plant and animal world. To date, over 520 ecdysteroids have been isolated from natural sources. The most accessible and studied representative of this class of compounds is 20-hydroxyecdysone (20E)—a universal hormone for the development and vital activity of insects and crustaceans. Moreover, ecdysteroids exhibit a wide spectrum of pharmacological activity for humans, without exerting toxic, androgenic, or estrogenic effects. In this regard, the search for new structures of ecdysteroids and their semi-synthetic analogs obtained as a result of various chemical transformations is in high demand. The review summarizes data for the period 2011–2021 regarding recent advances in the isolation of novel natural ecdysteroids, the chemical modifications, biological activity of semi-synthetic analogs and their prospects for practice.
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Total citations:
30
Citations from 2025:
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(33.33%)
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MLA
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GOST
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Savchenko R. G. et al. Ecdysteroids: isolation, chemical transformations, and biological activity // Phytochemistry Reviews. 2022. Vol. 21. No. 5. pp. 1445-1486.
GOST all authors (up to 50)
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Savchenko R. G., Veskina N. A., Odinokov V. N., Benkovskaya G. V., Parfenova L. V. Ecdysteroids: isolation, chemical transformations, and biological activity // Phytochemistry Reviews. 2022. Vol. 21. No. 5. pp. 1445-1486.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1007/s11101-021-09792-y
UR - https://doi.org/10.1007/s11101-021-09792-y
TI - Ecdysteroids: isolation, chemical transformations, and biological activity
T2 - Phytochemistry Reviews
AU - Savchenko, Rimma G.
AU - Veskina, Natalya A
AU - Odinokov, Viktor N.
AU - Benkovskaya, Galina V
AU - Parfenova, Lyudmila V.
PY - 2022
DA - 2022/01/04
PB - Springer Nature
SP - 1445-1486
IS - 5
VL - 21
SN - 1568-7767
SN - 1572-980X
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2022_Savchenko,
author = {Rimma G. Savchenko and Natalya A Veskina and Viktor N. Odinokov and Galina V Benkovskaya and Lyudmila V. Parfenova},
title = {Ecdysteroids: isolation, chemical transformations, and biological activity},
journal = {Phytochemistry Reviews},
year = {2022},
volume = {21},
publisher = {Springer Nature},
month = {jan},
url = {https://doi.org/10.1007/s11101-021-09792-y},
number = {5},
pages = {1445--1486},
doi = {10.1007/s11101-021-09792-y}
}
Cite this
MLA
Copy
Savchenko, Rimma G., et al. “Ecdysteroids: isolation, chemical transformations, and biological activity.” Phytochemistry Reviews, vol. 21, no. 5, Jan. 2022, pp. 1445-1486. https://doi.org/10.1007/s11101-021-09792-y.
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