International Journal of Biological Macromolecules

, volume 222 , issue Pt B , pages 1734-1746

Biocompatible formulation of cationic antimicrobial peptide Polylysine (PL) through nanotechnology principles and its potential role in food preservation — A review

S Karthick Raja Namasivayam ¹

Arun Ravi John ²

M. Kavisri ³

Meivelu Moovendhan ⁴

Hide authors affiliations Show authors affiliations: 4 affiliations

Department of Research and Innovation, Saveetha School of Engineering, SIMATS, Chennai 602105, Tamil Nadu, India |

Department of Molecular Analytics, Saveetha School of Engineering, SIMATS, Chennai 602105, Tamil Nadu, India |

Department of Civil Engineering, School of building and Environment, Sathyabama Institute of Science &Technology, Chennai 600119, Tamil Nadu, India |

⁴

Centre for Ocean Research, Sathyabama Institute of Science &Technology, Col. Dr. Jeppiaar Research Park, Chennai 600119, Tamil Nadu, India |

Publication type: Journal Article

Publication date: 2022-12-01

Elsevier

International Journal of Biological Macromolecules

scimago Q1

wos Q1

SJR: 1.285

CiteScore: 10.3

Impact factor: 8.5

ISSN: 01418130, 18790003

DOI: 10.1016/j.ijbiomac.2022.09.238

Copy DOI

PubMed ID: 36206840

Biochemistry

Molecular Biology

General Medicine

Structural Biology

Abstract

Food preservation using biopreservative agents mainly microbial based metabolites have gained more attention in the modern food sector due to their broad spectrum anti-microbial efficacy with high biocompatibility. However, the effectiveness of these biopreservatives is highly dependent on suitable formulation which will enhance the desired efficacy without affecting the nutritional value of the foods. Polylysine-actinomycete derived anti-microbial metabolite is used as biopreservative agent in various food products. This review provides a valuable insight into the formulation of polylysine with nanotechnology principles for enhanced antimicrobial efficacy against food spoilage organisms. This review highlighted the diverse methods of polylysine nanoformulation preparation. Formulation of polylysine as functionalised nanomaterials can be prepared via green science or green technology principles was extensively studied in this review. This study also revealed the methods for the determination of anti-microbial assays and biocompatibility tests in vitro and in vivo biocompatibility tests. Future prospects of nanoformulated polylysine in bio preservation can be extended to safe processing of canned and ready-to-eat food products without affecting the nutritional value of the foods.

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GOST |

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GOST Copy

S Karthick Raja Namasivayam et al. Biocompatible formulation of cationic antimicrobial peptide Polylysine (PL) through nanotechnology principles and its potential role in food preservation — A review // International Journal of Biological Macromolecules. 2022. Vol. 222. No. Pt B. pp. 1734-1746.

GOST all authors (up to 50) Copy

S Karthick Raja Namasivayam, John A. R., Kavisri M., Moovendhan M. Biocompatible formulation of cationic antimicrobial peptide Polylysine (PL) through nanotechnology principles and its potential role in food preservation — A review // International Journal of Biological Macromolecules. 2022. Vol. 222. No. Pt B. pp. 1734-1746.

RIS |

Cite this

RIS Copy

TY - JOUR

DO - 10.1016/j.ijbiomac.2022.09.238

UR - https://doi.org/10.1016/j.ijbiomac.2022.09.238

TI - Biocompatible formulation of cationic antimicrobial peptide Polylysine (PL) through nanotechnology principles and its potential role in food preservation — A review

T2 - International Journal of Biological Macromolecules

AU - S Karthick Raja Namasivayam

AU - John, Arun Ravi

AU - Kavisri, M.

AU - Moovendhan, Meivelu

PY - 2022

DA - 2022/12/01

PB - Elsevier

SP - 1734-1746

IS - Pt B

VL - 222

PMID - 36206840

SN - 0141-8130

SN - 1879-0003

ER -

BibTex |

Cite this

BibTex (up to 50 authors) Copy

@article{2022_S Karthick Raja Namasivayam,

author = {S Karthick Raja Namasivayam and Arun Ravi John and M. Kavisri and Meivelu Moovendhan},

title = {Biocompatible formulation of cationic antimicrobial peptide Polylysine (PL) through nanotechnology principles and its potential role in food preservation — A review},

journal = {International Journal of Biological Macromolecules},

year = {2022},

volume = {222},

publisher = {Elsevier},

month = {dec},

url = {https://doi.org/10.1016/j.ijbiomac.2022.09.238},

number = {Pt B},

pages = {1734--1746},

doi = {10.1016/j.ijbiomac.2022.09.238}

}

MLA

Cite this

MLA Copy

S. Karthick Raja Namasivayam, et al. “Biocompatible formulation of cationic antimicrobial peptide Polylysine (PL) through nanotechnology principles and its potential role in food preservation — A review.” International Journal of Biological Macromolecules, vol. 222, no. Pt B, Dec. 2022, pp. 1734-1746. https://doi.org/10.1016/j.ijbiomac.2022.09.238.

Publisher

Elsevier

Journal

International Journal of Biological Macromolecules

scimago Q1

wos Q1

SJR

1.285

CiteScore

10.3

Impact factor

8.5

ISSN

01418130 (Print)

18790003 (Electronic)

Profiles

Meivelu Moovendhan