Synthesis, volume 51, issue 13, pages 2667-2677

Hitchhiker’s Guide to Reductive Amination

Podyacheva Evgeniya ¹

Afanasyev Oleg I ¹

Tsygankov Alexey A. ¹

Makarova Maria ^{1, 2}

Chusov Denis ^{1, 3, 4}

Hide authors affiliations Show authors affiliations: 4 affiliations

Nesmeyanov Institute of Organoelement Compounds of the Russian Academy of Sciences |

Dmitry Mendeleev University of Chemical Technology of Russia |

Peoples’ Friendship University of Russia |

⁴

Moscow Institute of Physics and Technology |

Publication type: Journal Article

Publication date: 2019-04-17

Thieme

Journal: Synthesis

Quartile SCImago

Quartile WOS

Impact factor: 2.6

ISSN: 00397881, 1437210X

DOI: 10.1055/s-0037-1611788

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Catalysis

Organic Chemistry

Abstract

A comparative study of various widely used methods of reductive amination is reported. Specifically, such reducing agents as H2, Pd/C, hydride reagents [NaBH4, NaBH3CN, NaBH(OAc)3], and CO/Rh2(OAc)4 system were considered. For understanding the selectivity and activity of the reducing agents reviewed herein, different classes of starting materials were tested, including aliphatic and aromatic amines, as well as aliphatic and aromatic aldehydes and ketones. Most important advantages and drawbacks of the methods, such as selectivity of the target amine formation and toxicity of the reducing agents were compared. Methods were also considered from the viewpoint of green chemistry.

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Citations by journals

	1 2 3 4 5 6 7 8
European Journal of Organic Chemistry	European Journal of Organic Chemistry, 8, 12.9% European Journal of Organic Chemistry 8 publications, 12.9%
Journal of Organometallic Chemistry	Journal of Organometallic Chemistry, 5, 8.06% Journal of Organometallic Chemistry 5 publications, 8.06%
Journal of Organic Chemistry	Journal of Organic Chemistry, 3, 4.84% Journal of Organic Chemistry 3 publications, 4.84%
Organic Letters	Organic Letters, 3, 4.84% Organic Letters 3 publications, 4.84%
Organic and Biomolecular Chemistry	Organic and Biomolecular Chemistry, 3, 4.84% Organic and Biomolecular Chemistry 3 publications, 4.84%
Chemical Reviews	Chemical Reviews, 3, 4.84% Chemical Reviews 3 publications, 4.84%
Catalysis Science and Technology	Catalysis Science and Technology, 2, 3.23% Catalysis Science and Technology 2 publications, 3.23%
Chemistry - A European Journal	Chemistry - A European Journal, 2, 3.23% Chemistry - A European Journal 2 publications, 3.23%
Mendeleev Communications	Mendeleev Communications, 2, 3.23% Mendeleev Communications 2 publications, 3.23%
Journal of the American Chemical Society	Journal of the American Chemical Society, 2, 3.23% Journal of the American Chemical Society 2 publications, 3.23%
ChemCatChem	ChemCatChem, 2, 3.23% ChemCatChem 2 publications, 3.23%
ACS Omega	ACS Omega, 2, 3.23% ACS Omega 2 publications, 3.23%
ACS Catalysis	ACS Catalysis, 1, 1.61% ACS Catalysis 1 publication, 1.61%
Molecular Catalysis	Molecular Catalysis, 1, 1.61% Molecular Catalysis 1 publication, 1.61%
Organometallics	Organometallics, 1, 1.61% Organometallics 1 publication, 1.61%
Chemistry	Chemistry, 1, 1.61% Chemistry 1 publication, 1.61%
Science China Chemistry	Science China Chemistry, 1, 1.61% Science China Chemistry 1 publication, 1.61%
Molecules	Molecules, 1, 1.61% Molecules 1 publication, 1.61%
International Journal of Molecular Sciences	International Journal of Molecular Sciences, 1, 1.61% International Journal of Molecular Sciences 1 publication, 1.61%
Chemical Science	Chemical Science, 1, 1.61% Chemical Science 1 publication, 1.61%
Journal of Catalysis	Journal of Catalysis, 1, 1.61% Journal of Catalysis 1 publication, 1.61%
Chem Catalysis	Chem Catalysis, 1, 1.61% Chem Catalysis 1 publication, 1.61%
Nature Reviews Chemistry	Nature Reviews Chemistry, 1, 1.61% Nature Reviews Chemistry 1 publication, 1.61%
Current Opinion in Chemical Engineering	Current Opinion in Chemical Engineering, 1, 1.61% Current Opinion in Chemical Engineering 1 publication, 1.61%
ChemistrySelect	ChemistrySelect, 1, 1.61% ChemistrySelect 1 publication, 1.61%
Angewandte Chemie	Angewandte Chemie, 1, 1.61% Angewandte Chemie 1 publication, 1.61%
Angewandte Chemie - International Edition	Angewandte Chemie - International Edition, 1, 1.61% Angewandte Chemie - International Edition 1 publication, 1.61%
ChemPlusChem	ChemPlusChem, 1, 1.61% ChemPlusChem 1 publication, 1.61%
Journal of Medicinal Chemistry	Journal of Medicinal Chemistry, 1, 1.61% Journal of Medicinal Chemistry 1 publication, 1.61%
RSC Advances	RSC Advances, 1, 1.61% RSC Advances 1 publication, 1.61%

	1 2 3 4 5 6 7 8

Citations by publishers

	2 4 6 8 10 12 14 16 18
American Chemical Society (ACS)	American Chemical Society (ACS), 17, 27.42% American Chemical Society (ACS) 17 publications, 27.42%
Wiley	Wiley, 17, 27.42% Wiley 17 publications, 27.42%
Elsevier	Elsevier, 12, 19.35% Elsevier 12 publications, 19.35%
Royal Society of Chemistry (RSC)	Royal Society of Chemistry (RSC), 8, 12.9% Royal Society of Chemistry (RSC) 8 publications, 12.9%
Multidisciplinary Digital Publishing Institute (MDPI)	Multidisciplinary Digital Publishing Institute (MDPI), 3, 4.84% Multidisciplinary Digital Publishing Institute (MDPI) 3 publications, 4.84%
Springer Nature	Springer Nature, 3, 4.84% Springer Nature 3 publications, 4.84%
American Association for the Advancement of Science (AAAS)	American Association for the Advancement of Science (AAAS), 1, 1.61% American Association for the Advancement of Science (AAAS) 1 publication, 1.61%
	2 4 6 8 10 12 14 16 18

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Podyacheva E. et al. Hitchhiker’s Guide to Reductive Amination // Synthesis. 2019. Vol. 51. No. 13. pp. 2667-2677.

GOST all authors (up to 50) Copy

Podyacheva E., Afanasyev O. I., Tsygankov A. A., Makarova M., Chusov D. Hitchhiker’s Guide to Reductive Amination // Synthesis. 2019. Vol. 51. No. 13. pp. 2667-2677.

RIS |

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RIS Copy

TY - JOUR

DO - 10.1055/s-0037-1611788

UR - https://doi.org/10.1055%2Fs-0037-1611788

TI - Hitchhiker’s Guide to Reductive Amination

T2 - Synthesis

AU - Podyacheva, Evgeniya

AU - Afanasyev, Oleg I

AU - Tsygankov, Alexey A.

AU - Makarova, Maria

AU - Chusov, Denis

PY - 2019

DA - 2019/04/17 00:00:00

PB - Thieme

SP - 2667-2677

IS - 13

VL - 51

SN - 0039-7881

SN - 1437-210X

ER -

BibTex |

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@article{2019_Podyacheva,

author = {Evgeniya Podyacheva and Oleg I Afanasyev and Alexey A. Tsygankov and Maria Makarova and Denis Chusov},

title = {Hitchhiker’s Guide to Reductive Amination},

journal = {Synthesis},

year = {2019},

volume = {51},

publisher = {Thieme},

month = {apr},

url = {https://doi.org/10.1055%2Fs-0037-1611788},

number = {13},

pages = {2667--2677},

doi = {10.1055/s-0037-1611788}

}

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Podyacheva, Evgeniya, et al. “Hitchhiker’s Guide to Reductive Amination.” Synthesis, vol. 51, no. 13, Apr. 2019, pp. 2667-2677. https://doi.org/10.1055%2Fs-0037-1611788.

Found error?

Publisher

Thieme

Journal

Synthesis

Quartile SCImago

Quartile WOS

Impact factor

2.6

ISSN

00397881 (Print)
1437210X (Electronic)

Labs

Effective Catalysis Group

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