Dendrobium huoshanense stem polysaccharide ameliorates alcohol-induced gastric ulcer in rats through Nrf2-mediated strengthening of gastric mucosal barrier
Publication type: Journal Article
Publication date: 2023-05-01
scimago Q1
wos Q1
SJR: 1.285
CiteScore: 10.3
Impact factor: 8.5
ISSN: 01418130, 18790003
PubMed ID:
36907308
Biochemistry
Molecular Biology
General Medicine
Structural Biology
Abstract
This study aimed to explore whether Dendrobium huoshanense stem polysaccharide (cDHPS) ameliorates alcohol-induced gastric ulcer (GU) through the strengthening effect of the gastric mucosal barrier in rats and its potential mechanism. In normal rats, the pretreatment of cDHPS effectively strengthened gastric mucosal barrier by increasing mucus secretion and tight junction protein expression. In GU rats, cDHPS supplementation effectively alleviated alcohol-induced gastric mucosal injury and nuclear factor κB (NF-κB)-driven inflammation by strengthening gastric mucosal barrier. Moreover, cDHPS significantly activated nuclear factor E2-related factor 2 (Nrf2) signaling and promoted antioxidant enzymes activities in both normal and GU rats. These results suggested that the pretreatment of cDHPS could strengthen gastric mucosal barrier to inhibit oxidative stress and NF-κB-driven inflammation induced gastric mucosal injury, which was likely related to the activation of Nrf2 signaling.
Found
Nothing found, try to update filter.
Found
Nothing found, try to update filter.
Top-30
Journals
|
1
2
3
4
5
6
7
|
|
|
International Journal of Biological Macromolecules
7 publications, 14.29%
|
|
|
Food Bioscience
4 publications, 8.16%
|
|
|
Journal of Ethnopharmacology
4 publications, 8.16%
|
|
|
Nutrients
2 publications, 4.08%
|
|
|
Journal of Agricultural and Food Chemistry
2 publications, 4.08%
|
|
|
Carbohydrate Polymers
2 publications, 4.08%
|
|
|
Foods
2 publications, 4.08%
|
|
|
Journal of Functional Foods
2 publications, 4.08%
|
|
|
Molecules
1 publication, 2.04%
|
|
|
Chemistry and Biodiversity
1 publication, 2.04%
|
|
|
Journal of Food Biochemistry
1 publication, 2.04%
|
|
|
Drug Design, Development and Therapy
1 publication, 2.04%
|
|
|
Comprehensive Reviews in Food Science and Food Safety
1 publication, 2.04%
|
|
|
Biochemical Pharmacology
1 publication, 2.04%
|
|
|
Journal of Pharmaceutical Analysis
1 publication, 2.04%
|
|
|
APL Materials
1 publication, 2.04%
|
|
|
Frontiers in Plant Science
1 publication, 2.04%
|
|
|
Heliyon
1 publication, 2.04%
|
|
|
Food Safety and Health
1 publication, 2.04%
|
|
|
Current Opinion in Food Science
1 publication, 2.04%
|
|
|
Food and Function
1 publication, 2.04%
|
|
|
Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences
1 publication, 2.04%
|
|
|
Journal of Inflammation Research
1 publication, 2.04%
|
|
|
International Journal of Molecular Sciences
1 publication, 2.04%
|
|
|
Phytomedicine
1 publication, 2.04%
|
|
|
Bioorganic Chemistry
1 publication, 2.04%
|
|
|
Food Research International
1 publication, 2.04%
|
|
|
Frontiers in Immunology
1 publication, 2.04%
|
|
|
Industrial Crops and Products
1 publication, 2.04%
|
|
|
Journal of Future Foods
1 publication, 2.04%
|
|
|
1
2
3
4
5
6
7
|
Publishers
|
5
10
15
20
25
30
|
|
|
Elsevier
29 publications, 59.18%
|
|
|
MDPI
7 publications, 14.29%
|
|
|
Wiley
4 publications, 8.16%
|
|
|
American Chemical Society (ACS)
2 publications, 4.08%
|
|
|
Taylor & Francis
2 publications, 4.08%
|
|
|
Frontiers Media S.A.
2 publications, 4.08%
|
|
|
Hindawi Limited
1 publication, 2.04%
|
|
|
AIP Publishing
1 publication, 2.04%
|
|
|
Royal Society of Chemistry (RSC)
1 publication, 2.04%
|
|
|
5
10
15
20
25
30
|
- We do not take into account publications without a DOI.
- Statistics recalculated weekly.
Are you a researcher?
Create a profile to get free access to personal recommendations for colleagues and new articles.
Metrics
49
Total citations:
49
Citations from 2024:
44
(89.8%)
Cite this
GOST |
RIS |
BibTex
Cite this
GOST
Copy
Ye H. Yu. et al. Dendrobium huoshanense stem polysaccharide ameliorates alcohol-induced gastric ulcer in rats through Nrf2-mediated strengthening of gastric mucosal barrier // International Journal of Biological Macromolecules. 2023. Vol. 236. p. 124001.
GOST all authors (up to 50)
Copy
Ye H. Yu., Shang Z. Z., Zhang F., Zha X. Q., Li Q. M., Luo J. Dendrobium huoshanense stem polysaccharide ameliorates alcohol-induced gastric ulcer in rats through Nrf2-mediated strengthening of gastric mucosal barrier // International Journal of Biological Macromolecules. 2023. Vol. 236. p. 124001.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1016/j.ijbiomac.2023.124001
UR - https://doi.org/10.1016/j.ijbiomac.2023.124001
TI - Dendrobium huoshanense stem polysaccharide ameliorates alcohol-induced gastric ulcer in rats through Nrf2-mediated strengthening of gastric mucosal barrier
T2 - International Journal of Biological Macromolecules
AU - Ye, Hui Yu
AU - Shang, Zhen Zi
AU - Zhang, Fengyun
AU - Zha, Xue Qiang
AU - Li, Qiang Ming
AU - Luo, Jianping
PY - 2023
DA - 2023/05/01
PB - Elsevier
SP - 124001
VL - 236
PMID - 36907308
SN - 0141-8130
SN - 1879-0003
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2023_Ye,
author = {Hui Yu Ye and Zhen Zi Shang and Fengyun Zhang and Xue Qiang Zha and Qiang Ming Li and Jianping Luo},
title = {Dendrobium huoshanense stem polysaccharide ameliorates alcohol-induced gastric ulcer in rats through Nrf2-mediated strengthening of gastric mucosal barrier},
journal = {International Journal of Biological Macromolecules},
year = {2023},
volume = {236},
publisher = {Elsevier},
month = {may},
url = {https://doi.org/10.1016/j.ijbiomac.2023.124001},
pages = {124001},
doi = {10.1016/j.ijbiomac.2023.124001}
}