SHRESTHA, Rupendra
About
I specialize in ophthalmic research, focusing on stem cells, regenerative medicine, developmental biology, and genetic engineering of the human retina. My primary goal is to address retinal degeneration using a multifaceted approach integrating advanced techniques. I work with human pluripotent stem cells, including induced pluripotent and embryonic stem cells, and leverage organoid models, CRISPR gene editing, RPE transplantation, and 3-D nanofibrous scaffolding. By combining these state-of-the-art technologies, I aim to develop effective solutions for vision loss.
My research has yielded significant advancements in the field. I contributed to developing a unique retinal organoid model crucial for studying retinal function and disease mechanisms. My investigations extend to exploring axon pathfinding of retinal ganglion cells and optimizing cell patterning through stem cell applications. Notably, I have achieved the generation of large genomic deletions (15 kbp) using CRISPR/Cas9 technology. Through these efforts, I am committed to making impactful contributions to ophthalmic research and advancing our understanding of inherited retinal degeneration.
Research interests
Additional links
Education
Top-100
Fields of science
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5
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8
9
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General Medicine
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General Medicine, 9, 45%
General Medicine
9 publications, 45%
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Cell Biology
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Cell Biology, 2, 10%
Cell Biology
2 publications, 10%
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Developmental Biology
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Developmental Biology, 2, 10%
Developmental Biology
2 publications, 10%
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General Biochemistry, Genetics and Molecular Biology
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General Biochemistry, Genetics and Molecular Biology, 1, 5%
General Biochemistry, Genetics and Molecular Biology
1 publication, 5%
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Molecular Biology
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Molecular Biology, 1, 5%
Molecular Biology
1 publication, 5%
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Genetics
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Genetics, 1, 5%
Genetics
1 publication, 5%
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General Immunology and Microbiology
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General Immunology and Microbiology, 1, 5%
General Immunology and Microbiology
1 publication, 5%
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Cellular and Molecular Neuroscience
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Cellular and Molecular Neuroscience, 1, 5%
Cellular and Molecular Neuroscience
1 publication, 5%
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General Neuroscience
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General Neuroscience, 1, 5%
General Neuroscience
1 publication, 5%
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Ophthalmology
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Ophthalmology, 1, 5%
Ophthalmology
1 publication, 5%
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Sensory Systems
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Sensory Systems, 1, 5%
Sensory Systems
1 publication, 5%
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1
2
3
4
5
6
7
8
9
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Journals
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2
3
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Molecular Biology Reports
3 publications, 15%
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Tissue and Cell
1 publication, 5%
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Stem Cell Research
1 publication, 5%
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Platelets
1 publication, 5%
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Journal of the Nepal Medical Association
1 publication, 5%
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Current Eye Research
1 publication, 5%
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Brazilian Dental Science
1 publication, 5%
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Case Reports in Medicine
1 publication, 5%
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Tzu Chi Medical Journal
1 publication, 5%
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eLife
1 publication, 5%
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PLoS ONE
1 publication, 5%
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Cells
1 publication, 5%
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Infectious Microbes & Diseases
1 publication, 5%
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Acta Medica International
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Acta Medica International, 1, 5%
Acta Medica International
1 publication, 5%
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Progress in Stem Cell
1 publication, 5%
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1
2
3
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Citing journals
Publishers
1
2
3
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Springer Nature
3 publications, 15%
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Elsevier
2 publications, 10%
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Taylor & Francis
2 publications, 10%
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Ovid Technologies (Wolters Kluwer Health)
2 publications, 10%
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MDPI
1 publication, 5%
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Public Library of Science (PLoS)
1 publication, 5%
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Nepal Medical Association
1 publication, 5%
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Universidade Estadual Paulista, Institute of Science and Technology of Sao Jose dos Campo
1 publication, 5%
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eLife Sciences Publications
1 publication, 5%
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Hindawi Limited
1 publication, 5%
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Biomedical Research and Therapy
1 publication, 5%
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1
2
3
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Organizations from articles
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4
6
8
10
12
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Organization not defined
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Organization not defined, 12, 54.55%
Organization not defined
12 publications, 54.55%
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Tzu Chi University
3 publications, 13.64%
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Albert Einstein College of Medicine
3 publications, 13.64%
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Indian Institute of Technology Madras
1 publication, 4.55%
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Madurai Kamaraj University
1 publication, 4.55%
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Shanmugha Arts, Science, Technology & Research Academy
1 publication, 4.55%
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Indira Gandhi Centre for Atomic Research
1 publication, 4.55%
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4
6
8
10
12
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Countries from articles
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4
6
8
10
12
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Country not defined
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Country not defined, 11, 39.29%
Country not defined
11 publications, 39.29%
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India
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India, 5, 17.86%
India
5 publications, 17.86%
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USA
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USA, 4, 14.29%
USA
4 publications, 14.29%
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Australia
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Australia, 4, 14.29%
Australia
4 publications, 14.29%
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China
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China, 3, 10.71%
China
3 publications, 10.71%
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Nepal
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Nepal, 1, 3.57%
Nepal
1 publication, 3.57%
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2
4
6
8
10
12
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Citing organizations
Citing countries
2
4
6
8
10
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16
18
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China
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China, 17, 21.52%
China
17 citations, 21.52%
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Country not defined
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Country not defined, 11, 13.92%
Country not defined
11 citations, 13.92%
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USA
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USA, 11, 13.92%
USA
11 citations, 13.92%
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India
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India, 7, 8.86%
India
7 citations, 8.86%
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Iran
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Iran, 5, 6.33%
Iran
5 citations, 6.33%
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Republic of Korea
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Republic of Korea, 3, 3.8%
Republic of Korea
3 citations, 3.8%
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Germany
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Germany, 2, 2.53%
Germany
2 citations, 2.53%
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Australia
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Australia, 2, 2.53%
Australia
2 citations, 2.53%
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United Kingdom
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United Kingdom, 2, 2.53%
United Kingdom
2 citations, 2.53%
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Spain
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Spain, 2, 2.53%
Spain
2 citations, 2.53%
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Italy
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Italy, 2, 2.53%
Italy
2 citations, 2.53%
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Poland
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Poland, 2, 2.53%
Poland
2 citations, 2.53%
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Japan
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Japan, 2, 2.53%
Japan
2 citations, 2.53%
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Russia
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Russia, 1, 1.27%
Russia
1 citation, 1.27%
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France
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France, 1, 1.27%
France
1 citation, 1.27%
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Portugal
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Portugal, 1, 1.27%
Portugal
1 citation, 1.27%
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Bangladesh
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Bangladesh, 1, 1.27%
Bangladesh
1 citation, 1.27%
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Belgium
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Belgium, 1, 1.27%
Belgium
1 citation, 1.27%
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Egypt
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Egypt, 1, 1.27%
Egypt
1 citation, 1.27%
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Canada
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Canada, 1, 1.27%
Canada
1 citation, 1.27%
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Netherlands
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Netherlands, 1, 1.27%
Netherlands
1 citation, 1.27%
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Serbia
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Serbia, 1, 1.27%
Serbia
1 citation, 1.27%
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Thailand
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Thailand, 1, 1.27%
Thailand
1 citation, 1.27%
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Switzerland
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Switzerland, 1, 1.27%
Switzerland
1 citation, 1.27%
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18
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- We do not take into account publications without a DOI.
- Statistics recalculated daily.